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Kaye Foster

Lead Independent Director at AGIOS PHARMACEUTICALSAGIOS PHARMACEUTICALS
Board

About Kaye Foster

Kaye Foster, 65, has served on Agios’s board since December 2014 and is the Lead Independent Director. She brings nearly 30 years of HR leadership in pharma (Pfizer, Johnson & Johnson, Onyx Pharmaceuticals), is a Senior Advisor at Boston Consulting Group (since 2014) and a Venture Partner at ARCH Venture Partners (since January 2022). She holds a BBA from Baruch College and an MBA from Columbia Business School .

Past Roles

OrganizationRoleTenureCommittees/Impact
Onyx Pharmaceuticals (Amgen subsidiary)Senior Vice President, Global HR2010–2014Led all HR; supported U.S. and global operations
Johnson & JohnsonGlobal Vice President of HR; Executive Committee member2003–2010Global HR leadership
PfizerSenior HR executive rolesNot disclosed (prior to 2003)Supported pharma businesses across Japan/Asia/Africa/Middle East/LatAm; led Warner-Lambert and Pharmacia integrations in these regions
The Yellow PagesOperational roles~10 years (prior to Pfizer)Operational experience

External Roles

OrganizationRoleTenureCommittees/Impact
Prime Medicine, Inc. (public)DirectorCurrentCompensation Committee member
National Resilience Inc. (private)DirectorCurrentCompensation & Community Equity Committee member
Xaira Therapeutics (private)DirectorCurrentCompensation Committee; Nominating & Corporate Governance Committee
Spelman CollegeBoard memberCurrentHuman Resources Committee
Glide FoundationBoard of TrusteesCurrentTrustee
GRAIL, Inc. (private, acquired by Illumina)DirectorFormerCompensation Committee member
Stanford Health CareDirectorFormerCompensation and Facilities Committees
Boston Consulting GroupSenior AdvisorSince 2014Advisory role
ARCH Venture PartnersVenture PartnerSince Jan 2022Venture role

Board Governance

  • Independence: The board determined Ms. Foster is independent under Nasdaq Rule 5605(a)(2); AGIO’s CEO (Brian Goff) and Chair (Jacqualyn Fouse) are not independent .
  • Lead Independent Director: Appointed due to non-independent chair; duties include chairing executive sessions, facilitating board–management communications, helping set agendas, monitoring shareholder communications, and consulting on governance/board performance .
  • Committees: Chair, Nominating & Corporate Governance; Member, Compensation & People .
  • Committee activity: Compensation & People met 7 times in FY2024; Nominating & Corporate Governance met 3 times in FY2024 .
  • Attendance: Board met 7 times in FY2024; each then-serving director attended ≥75% of board and committee meetings; 9 of 10 directors attended the 2024 annual meeting .

Fixed Compensation

ComponentFY 2024 Actual ($)Policy 2025 Cash ($)
Board retainer and committee/lead fees (cash)92,500 Board Member: 50,000; Lead Independent Director: +30,000; Nominating & Corporate Governance Chair: +10,000; Compensation & People Member: +8,750; Total expected per policy given current roles: 98,750

Notes:

  • 2025 policy increased certain cash roles (Chair +$35k; LID +$30k; Comp & People chair +$17.5k; member +$8.75k) and raised annual director equity value to $400k to align with market medians .

Performance Compensation

ComponentFY 2024 AwardsVestingGrant-Date Fair Value ($)
Stock Options11,774 optionsVest 100% on June 20, 2025266,287
RSUs2,120 sharesVest 100% on June 20, 202589,994
Equity Policy (non-employee directors)ValueMixVestingTerms
Initial election (policy eff. 1/1/2025)630,000~75% options / ~25% RSUsOptions: 25% first anniversary, then monthly to 4 years; RSUs: one-third annually for 3 yearsOptions expire in 10 years; strike = FMV at grant
Annual grant (policy eff. 1/1/2025)400,000~75% options / ~25% RSUs100% on first anniversary (options and RSUs)Options expire in 10 years; strike = FMV at grant

Additional governance controls:

  • No option repricing; hedging and pledging prohibited under insider trading policy .
  • Clawback policy compliant with SEC Rule 10D-1; recovery of incentive-based compensation upon restatements; pre-2023 awards covered by prior clawback policy .

Performance metrics tied to director compensation: Not disclosed (director equity is time-based; performance PSU metrics apply to executives, not directors) .

Other Directorships & Interlocks

CompanySectorRelationship to AGIONotes
Prime Medicine, Inc.Biotechnology (public)No related-party transactions disclosedServes on Compensation Committee
National Resilience Inc.Biomanufacturing (private)No related-party transactions disclosedServes on Compensation & Community Equity Committee
Xaira TherapeuticsBiotechnology (private)No related-party transactions disclosedServes on Compensation and Nominating & Corporate Governance Committees

Policy context: Related person transactions ≥$120,000 require audit committee review/approval; none since Jan 1, 2024 .

Expertise & Qualifications

  • Deep HR leadership in global pharma, including M&A integration (Warner-Lambert and Pharmacia integrations across multiple regions), compensation planning, and culture stewardship .
  • Governance leadership as Lead Independent Director and committee chair; oversight of ESG programs, succession planning, and HR/talent initiatives .
  • Education: BBA (Baruch College), MBA (Columbia Business School) .

Equity Ownership

As-of DateShares Owned+ Options/Other Rights Exercisable ≤60 Days= Total Beneficial Ownership% of Outstanding
March 31, 20257,548 (incl. Foster Family Revocable Trust) 62,767 70,315 <1% (of 57,886,781 shares)
Additional Detail (Outstanding Awards)Balance
Options outstanding as of Dec 31, 202474,541
RSUs outstanding as of Dec 31, 20242,120

Ownership alignment:

  • Director stock ownership guidelines: non-employee directors must hold ≥3x annual cash retainer; compliance confirmed for all directors as of March 31, 2025 (phase-in exception applies to certain directors, not Ms. Foster) .
  • Hedging and pledging prohibited; margin purchases restricted, aligning with investor-protection practices .

Governance Assessment

  • Board effectiveness: Foster serves as Lead Independent Director with defined responsibilities to coordinate independent director sessions, agendas, and shareholder communications—strengthening independent oversight while the chair is non-independent .
  • Engagement: Active committee leadership (chair of Nominating & Corporate Governance; member of Compensation & People). Committees met regularly in 2024 (Comp: 7; Nominating: 3). Board-level attendance ≥75% for all directors—positive engagement signal .
  • Independence and conflicts: Board affirmed her independence; no related-party transactions involving directors since Jan 1, 2024; robust related-party review procedures are in place—low conflict risk signal .
  • Pay structure and alignment: 2024 compensation mix tilted toward equity (options and RSUs) with one-year vesting; 2025 policy increases annual equity to $400k and maintains time-based vesting, with prohibitions on option repricing and hedging/pledging—generally shareholder-friendly guardrails .
  • Ownership alignment: Complies with director ownership guidelines; beneficial ownership includes trust-held shares; anti-pledging policy reduces alignment risk .
  • Guardrails: Director equity cap under the plan ($750k per incumbent director per year; $1,000k initial year) adds compensation discipline .

Red flags: None disclosed (no related-party transactions; strong attendance; anti-hedging/pledging; clawback policy). Monitoring items: Multiple external biotech/biomanufacturing affiliations warrant continued oversight under AGIO’s related-person policy should commercial transactions arise, but none are disclosed to date .