Artivion Inc (AORT)

Abbott Laboratories

Competes with On-X heart valves based on features such as full, 90-degree leaflet opening, pure pyrolytic carbon, flared inlet, and approved labeling claim for reduced INR for aortic valves. "

Medtronic PLC

Competes with On-X heart valves and other products in the cardiac and vascular space, leveraging its established market presence and product portfolio. " "

Corcym

Competes with On-X heart valves following its acquisition of the LivaNova heart valve business in June 2021. "

LifeNet Health

Competes in the preserved human heart valves and patches market, leveraging surgeon preference, clinical data, and customer service. "

LeMaitre Vascular Inc

Competes in preserved human heart valves and patches, as well as vascular tissue preservation services. " "

Edwards Lifesciences Corp

Competes with bioprosthetic and mechanical valves and xenograft products in the cardiac and vascular space. "

Anteris Technologies

Competes with xenograft products in the cardiac and vascular patch market. "

Baxter International Inc

Competes with surgical sealants and bioprosthetic cardiac and vascular patches, leveraging its product features and benefits. " "

Cook Medical

Competes with customized and off-the-shelf stent graft systems for thoraco-abdominal aneurysms and other vascular conditions. " "

Gore

Competes with thoracic extension products, stent graft systems, and synthetic vascular grafts in the aortic and peripheral vascular markets. " " "

Terumo

Competes with customized stent graft systems and synthetic vascular grafts, leveraging its established market presence. " " "

Becton Dickinson and Co

Competes with synthetic vascular grafts and surgical sealants, leveraging its product portfolio and market reach. " "

Maquet

Competes with synthetic vascular grafts and balloon-expandable peripheral stent grafts. "

Bentley InnoMed

Competes with balloon-expandable peripheral stent grafts, leveraging its product features and approvals. "

Ethicon (a Johnson & Johnson Company)

Competes with surgical sealants, leveraging its established market presence and product portfolio. "

Integra Lifesciences Holdings Corp

Competes with surgical sealants, leveraging its product features and benefits. "

Pfizer Inc

Competes in the broader medical device and pharmaceutical markets, leveraging its extensive resources and market presence. "

BioCer Entwicklungs-GmbH

Competes in the surgical sealants market, leveraging its product features and benefits. "

Elutia (formerly Aziyo Biologics)

Competes in the tissue preservation and medical device markets, leveraging its product offerings. "

Endospan Ltd.

2024

Planned acquisition with an upfront payment reduced to $135 million (down from a proposed $250 million), elimination of the $100 million minimum earnout while retaining a maximum earnout of $200 million structured as 2.5x incremental year-two revenue; additionally, up to $25 million in secured loans at 5% interest are provided in three tranches, all contingent on FDA approval of its NEXUS Stent Graft System – the first approved branched endovascular system for aortic arch disease with an estimated $600 million annual market opportunity. " " " " "

Ascyrus Medical LLC

2020

Completed acquisition signed on September 2, 2020, with a total consideration of up to $200 million including initial cash and stock payments and various milestone-based regulatory approvals; Ascyrus, known for its development of the Ascyrus Medical Dissection Stent (AMDS), enhances access to over $100 million in EU and Canadian markets and offers substantial global cross-selling benefits for CryoLife’s portfolio. " " "