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Mark DeLong

Chief Business & Strategy Officer at Apellis PharmaceuticalsApellis Pharmaceuticals
Executive

About Mark DeLong

Mark DeLong is Chief Business & Strategy Officer at Apellis Pharmaceuticals (APLS), age 48, with responsibility for business development and strategic planning; he has served in this capacity since January 2023 after joining Apellis in February 2018 and progressing through VP and SVP roles in strategy and BD . Prior roles include leadership at EMD Serono (Head of US Business Development; Head of Global Portfolio Management, Neurology & Immunology) and Managing Director at Bluepoint Healthcare Consulting; he holds a B.S. from Penn State and an MBA from the University of Michigan . Under Apellis’ company-wide compensation programs, short-term incentives (FY2024) paid at 90.74% of target based on product revenue, regulatory, pipeline, and operational goals, and the company introduced 50% PSU/50% RSU long-term incentives tied to relative TSR starting 2025 . Company execution during his tenure included 2024 revenue of $781.4M (+97% y/y), continued U.S. leadership of SYFOVRE in GA, and FDA approval of EMPAVELI for C3G/IC-MPGN on July 28, 2025, supporting commercialization momentum and value creation .

Past Roles

OrganizationRoleYearsStrategic impact
Apellis PharmaceuticalsChief Business & Strategy OfficerJan 2023 – presentLeads business development and corporate strategy
Apellis PharmaceuticalsSVP, Business Development & StrategyFeb 2020 – Jan 2023Advanced BD and strategy functions
Apellis PharmaceuticalsVP, Business Development & StrategyNov 2018 – Feb 2020Built BD pipeline and partnerships
Apellis PharmaceuticalsVP, Strategy & OperationsFeb 2018 – Nov 2018Established strategy/operations foundation
EMD SeronoHead, Global Portfolio Mgmt., Neuro & ImmunologySep 2017 – Jan 2018Portfolio oversight in neuro/immunology
EMD SeronoHead, US Business DevelopmentOct 2012 – Jul 2016Led U.S. BD transactions
Bluepoint Healthcare ConsultingManaging DirectorJul 2016 – Jun 2017Consulting leadership

External Roles

OrganizationRoleYearsNotes
No public company directorships or external board roles disclosed in proxy materials

Fixed Compensation

  • Individual base salary, target bonus %, and actual bonus for Mr. DeLong are not disclosed; Apellis’ proxy reports detailed compensation for named executive officers (NEOs), a group that does not include Mr. DeLong for 2024–2025 .
  • Company program design (applies to executive officers generally): base salary reviewed annually versus peers; 2024 annual bonus funded at 90.74% of target based on corporate goals; 2025 maintained target bonus %s for NEOs and introduced PSUs for long-term incentives .

Performance Compensation

  • Annual cash incentive mechanics (company-wide): bonuses based on corporate goals across product revenue, regulatory milestones, pipeline progress (e.g., APL-3007), and operational objectives; 2024 corporate performance factor = 90.74% .
Metric/Plan (company-wide)WeightingTargetActual/OutcomePayoutVesting/Notes
2024 Corporate Performance FactorNot disclosed100%90.74%90.74% of target bonuses for execs Paid Feb 2025 (timing per program)
2025 PSUs (execs) – Relative TSR vs NASDAQ Biotech50% of LTI value (PSUs) 25th/55th/90th percentile thresholds50%/100%/200% of target shares at 25th/55th/90th percentiles; capped at 100% if absolute TSR negative 50%–200%Three performance periods: 2025 (1yr), 2025–26 (2yr), 2025–27 (3yr), vest post-period
2025 RSUs (execs)50% of LTI value (RSUs) N/ATime-basedN/A25% per year over 4 years

Notes: Weightings of annual bonus sub-metrics and individual targets for Mr. DeLong are not disclosed .

Equity Ownership & Alignment

  • Beneficial ownership: Individual holdings for Mr. DeLong are not itemized; the proxy lists 5% holders, directors, and NEOs. All directors and executive officers as a group (14 persons) held 8,383,034 shares/options (6.5%) as of Mar 31, 2025, indicating meaningful insider alignment .
  • Ownership guidelines: CEO 6x salary; other executive officers 1–3x salary depending on title; 5-year compliance window; as of Dec 31, 2024, all directors and executive officers met the guidelines (implies Mr. DeLong, as an executive officer, was in compliance) .
  • Hedging/pledging: Hedging prohibited; pledging prohibited unless Audit Committee grants an exception (one such exception for a director in 2024). No pledging exceptions disclosed for Mr. DeLong .
  • Trading plans: Executives may use Rule 10b5-1 plans for pre-scheduled trades; such plans are permitted under company policy .
  • Filing history: One late Section 16 Form 4 for Mr. DeLong was noted for an RSU grant dated Oct 20, 2021 (filed Oct 27, 2021) .

Employment Terms

  • Executive Separation Benefits & Retention Plan (coverage): Applies to “C-level officers” (CEO, CFO, CMO, COO, GC) and certain other executives VP+ designated by the board; Mr. DeLong is a C-level executive officer (CB&SO). The proxy does not explicitly list covered individuals by name, but outlines the plan terms below .
  • Not-for-cause termination (outside change of control): Salary continuation (CEO 12 months; other C-level officers 9 months) and COBRA premium contributions for the severance period .
  • Change of control (within 12 months; double-trigger): Lump-sum salary (CEO 18 months; other C-level 12 months), target bonus (CEO 150%; others 100%), COBRA contributions, outplacement, and full acceleration of time-based equity (performance awards follow plan terms) .
  • Clawback/recoupment: Adopted in Dec 2023; recovery of incentive compensation after restatements, misconduct, or serious financial/reputational damage (up to 100% at board discretion) .
  • Non-compete/non-solicit: The proxy explicitly confirms one-year non-compete and non-solicit agreements for NEOs; it does not specifically enumerate Mr. DeLong’s agreement .

Performance & Track Record

IndicatorDetail
Revenue and growthFY2024 revenue $781.4M (+97% y/y), with $710M U.S. net product revenue from EMPAVELI and SYFOVRE
SYFOVRE commercialization>510k doses delivered since U.S. launch in Mar 2023 through YE2024; market-leading GA treatment; Australia approval in Jan 2025
EMPAVELI nephrology expansionFDA approval for C3G and primary IC-MPGN on July 28, 2025; launch underway
PipelinePreparing 2H25 starts for pivotal FSGS and DGF studies; advancing APL-3007 combination strategy in GA (Phase 2 planned 2Q25)
Governance/say-on-pay2024 say-on-pay support >89.9% indicating strong shareholder backing for pay programs
Legal proceedingsNo material legal proceedings involving directors or executive officers disclosed

Compensation Structure Diagnostics (pay-for-performance levers)

  • Shift to PSUs tied to relative TSR (50% of LTI in 2025), with a cap at target for negative absolute TSR, is shareholder-friendly and increases at-risk pay sensitivity to market-relative performance .
  • Annual bonus funding at 90.74% in 2024 reflects below-target performance on aggregate corporate goals (including product revenue thresholds and regulatory outcomes), showing discipline in variable pay .
  • Stock ownership guidelines and anti-hedging/limited-pledging policies reinforce alignment; all executive officers met ownership requirements as of YE2024 .
  • Double-trigger change-in-control protection with equity acceleration mitigates “single-trigger windfall” risk while still supporting retention during strategic events .

Risk Indicators & Red Flags

  • Pledging/hedging: Company-wide prohibitions with controlled exceptions; no exceptions disclosed for Mr. DeLong (mitigates alignment risk) .
  • Clawbacks: Enhanced policy (Dec 2023) covering restatements and misconduct reduces risk of misaligned incentives .
  • Section 16 compliance: One late filing for Mr. DeLong in 2021—an administrative timing issue rather than a trading practice concern .
  • Governance: Strong say-on-pay approval (89.9%) suggests low shareholder dissent on executive pay .

Compensation Peer Group (benchmarking context)

2025 Peer Companies (selected by Compensation Committee)
ACADIA, Alkermes, Amicus, Axsome, Biocryst, Blueprint, Corcept, Insmed, Intra-Cellular, Ionis, Madrigal, Neurocrine, PTC, Ultragenyx

Investment Implications

  • Incentive alignment: The 2025 introduction of relative-TSR PSUs (with downside cap for negative absolute TSR) meaningfully increases performance linkage and reduces windfalls in weak markets—supportive for long-term holders monitoring insider motivation .
  • Selling pressure timing: RSUs vest annually (25% per year) and options vest monthly after the first year; executives can use Rule 10b5-1 plans—expect potential periodic Form 4 sales clustered around vest dates, though hedging/pledging is restricted and ownership guidelines apply .
  • Retention risk and COC economics: Double-trigger severance and full time-based equity acceleration under change-of-control are competitive but not excessive; they should stabilize leadership through strategic events while avoiding single-trigger optics .
  • Data limitations: Mr. DeLong is not a named executive officer, so precise base/bonus and grant-level detail are not disclosed; monitoring future proxies and Section 16 filings (Form 4) is recommended to quantify ownership changes and potential selling cadence .