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    Alterity Therapeutics Ltd (ATHE)

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    Alterity Therapeutics Limited (ATHE) is a biotechnology company specializing in the development of therapeutic drugs for neurodegenerative diseases, with a primary focus on Parkinsonian disorders and related movement disorders. The company is a development-stage enterprise, advancing its pharmaceutical products through early to mid-stage clinical trials. Alterity does not sell commercial products but generates revenue through government grants, licensing, research collaborations, and interest income.

    1. Research and Development in Neurodegenerative Diseases - Focuses on discovering and developing therapeutic drugs targeting Parkinsonian disorders, including Multiple System Atrophy (MSA), a rare and debilitating condition with no approved treatments.
      • ATH434 - Lead drug candidate in Phase 2 clinical trials for MSA, designed to address the underlying pathology of the disease.
      • PBT2 - Previously developed for Alzheimer’s and Huntington diseases, with completed Phase 1 and Phase 2 trials.
    2. Discovery Platform - Maintains a chemical library of over 1,000 validated compounds designed for oral bioavailability and blood-brain barrier penetration, targeting the interrelationship of metals and proteins in neurodegenerative diseases.
    3. Collaborative Research - Partners with leading scientists and institutions, conducting research at The University of Melbourne’s Bio21 Molecular Science and Biotechnology Institute.
    NamePositionStart DateShort Bio
    Dr. David StamlerChief Executive OfficerJanuary 2021Dr. Stamler was appointed CEO of Alterity Therapeutics in January 2021. He previously served as Chief Medical Officer and SVP, Clinical Development at Alterity since May 2017. He has extensive experience in clinical development and leadership roles, including at Teva Pharmaceutical Industries and Auspex Pharmaceuticals. He holds an M.D. and a B.A. in Biology from the University of Chicago.
    Mr. Phillip HainsChief Financial OfficerJanuary 31, 2024Mr. Hains has served as CFO of Alterity Therapeutics since January 31, 2024 (expected start date). He has over 30 years of experience as a Chartered Accountant, specializing in financial reporting and compliance. He has been with Alterity since November 2014 as Company Secretary and operates through Acclime Australia.