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    Cencora (COR)

    COR Q3 2025: US operating income +29%, EPS guidance 8%-12%

    Reported on Aug 6, 2025 (Before Market Open)
    Pre-Earnings Price$292.35Last close (Aug 5, 2025)
    Post-Earnings Price$282.11Open (Aug 6, 2025)
    Price Change
    $-10.24(-3.50%)
    • Robust U.S. Healthcare Performance: Executives highlighted accelerated operating income growth—up to 29% in the U.S. segment—driven by strong specialty product sales and effective execution despite moderated revenue growth, indicating resilient core operations.
    • Successful RCA Integration: Management noted the excellent cultural and operational fit from the recent RCA acquisition with positive customer feedback, which is expected to enhance specialty services and provide new growth avenues.
    • Resilient Approach to External Risks: Leadership addressed tariff uncertainties and potential policy headwinds, emphasizing ongoing monitoring, adaptation in sourcing practices, and sequential improvements in international logistics, which supports a stable outlook.
    • Moderating U.S. Healthcare revenue growth: Several questions raised concerns over slowing top‐line drivers, including moderated GLP‑1 growth, a loss of a high revenue customer, and softer biosimilar performance, which could weigh on overall U.S. revenue despite strong operating income growth.
    • Underperformance in international segments: Analysts highlighted that the international business is facing headwinds due to sluggish clinical trial activity and declining margins in higher‑margin specialty logistics and consulting, suggesting potential ongoing challenges outside the U.S..
    • Political and regulatory uncertainties: Discussion around tariffs, evolving policies (e.g., hospital outpatient rules), and broader political commentary indicates possible regulatory risks that may disrupt supply chains or erode profitability, adding uncertainty to future earnings.
    MetricPeriodPrevious GuidanceCurrent GuidanceChange

    Adjusted Diluted EPS Guidance

    FY 2025

    $15.70 to $15.95; Growth 14% to 16%; Increase from $15.30 to $15.60

    $15.85 to $16; Growth 15% to 16%

    raised

    Consolidated Revenue Guidance

    FY 2025

    Growth 8% to 10%; unchanged

    Approximately 9%

    no change

    U.S. Healthcare Solutions Segment Revenue Growth

    FY 2025

    Unchanged

    9% to 10%

    no prior guidance

    International Healthcare Solutions Segment Revenue (As‐reported)

    FY 2025

    3% to 4% (down from 4% to 5%)

    6% to 7%

    raised

    International Healthcare Solutions Segment Revenue (Constant currency)

    FY 2025

    6% to 8% (down from 7% to 9%)

    7% to 8%

    raised

    Consolidated Operating Income Growth Guidance

    FY 2025

    13.5% to 15.5% (up from 11.5% to 13.5%)

    15% to 16%

    raised

    U.S. Healthcare Solutions Segment Operating Income Growth

    FY 2025

    17.5% to 19.5% (up from 14.5% to 16.5%)

    20% to 21%

    raised

    International Healthcare Solutions Segment Operating Income (As‐reported)

    FY 2025

    Down 4% to down 1%

    Down approximately 6%

    lowered

    International Healthcare Solutions Segment Operating Income (Constant currency)

    FY 2025

    Down 3% to flat

    Down approximately 5%

    lowered

    Adjusted Free Cash Flow Guidance

    FY 2025

    $2 billion to $3 billion

    $2,000,000,000 to $3,000,000,000

    no change

    TopicPrevious MentionsCurrent PeriodTrend

    U.S. Healthcare Specialty Performance

    Q2 2025 discussions highlighted strong specialty revenue growth, broad-based performance and robust investments ( ), Q1 2025 emphasized broad-based specialty strength with strategic investments, and Q4 2024 focused on growth driven by specialty products and GLP-1 contributions ( )

    Q3 2025 called out strong specialty performance with key growth drivers, notable operating income improvements, and continued strategic investments ( )

    The sentiment remains bullish and consistent, with increased emphasis on investments and execution in specialty segments

    RCA Acquisition Integration and MSO Expansion

    Q2 2025 highlighted integration progress and MSO expansion as value drivers ( ); Q1 2025 stressed the strategic acquisition of RCA and its role in enhancing the MSO model ( ); Q4 2024 detailed transaction funding and strategic fit with MSO support ( )

    Q3 2025 reported strong integration progress of RCA and strategic expansion into MSOs with positive cultural and operational feedback ( )

    The topic remains a core strategic focus, with steady integration and an evolving emphasis on expanding MSO-related capabilities

    GLP-1 Product Growth and Margin Concerns

    Q2 2025 noted robust revenue growth in GLP-1 products despite low profitability ( ); Q1 2025 emphasized high revenue growth with persistent low margins ( ); Q4 2024 discussed significant GLP-1 growth causing margin pressure ( )

    Q3 2025 reported moderated growth in GLP-1 sales while reiterating their minimal contribution to operating income ( )

    Consistent high growth paired with persistent margin concerns; growth is moderating while low profitability remains a challenge

    International Operations and Global Logistics Challenges

    Q2 2025 pointed to revenue growth in Europe with softness in logistics due to sluggish clinical trial activity ( ); Q1 2025 noted revenue and operating income mixed results with competitive dynamics and clinical trial impacts ( ); Q4 2024 focused on revenue gains offset by higher IT and currency pressures ( )

    Q3 2025 revealed solid revenue gains in the international segment with operating income under pressure from soft global specialty logistics, though sequential improvements are emerging ( )

    Ongoing challenges persist across regions with pressures on operating income but with signs of sequential recovery and optimism for market rebound

    Political, Regulatory, and External Risks

    Q4 2024 discussed the IRA impact and legislative adaptability ( ); Q2 2025 stressed monitoring tariffs and engaging in advocacy while noting minimal direct impact ( ); Q1 2025 did not mention these risks

    Q3 2025 focused on tariffs, noting active monitoring and no material impacts, with no discussion of IRA or heightened regulatory scrutiny ( )

    While earlier periods featured broader discussions (including IRA) and active advocacy, current sentiment narrows to tariff monitoring with stable, minimal immediate impact

    Expansion into New Specialties

    Q4 2024 emphasized strategic expansion in oncology and ophthalmology via OneOncology and RCA ( ); Q1 2025 highlighted investments in OneOncology and RCA to bolster oncology and retina, with a clear MSO strategy ( ); Q2 2025 reinforced the same with detailed clinical trial ambitions and future capital deployment ( )

    Q3 2025 underlined continued investments in oncology and ophthalmology, with OneOncology initiatives playing a key role despite some customer losses in oncology ( )

    The expansion remains a high-impact strategic priority with consistent investments and a positive outlook, despite minor execution challenges in certain segments

    Emerging Diversification in Animal Health

    Q1 2025 mentioned strong performance and market share gains in Animal Health, noting 7% top‐line growth across companion and production animal segments ( )

    Q3 2025 did not address this topic

    The absence in the current period suggests a diminished emphasis or lower priority compared to specialty and integration initiatives

    Acquisition Financing and Cost Pressures

    Q4 2024 detailed debt and cash mix for the RCA acquisition and highlighted margin pressures from cost increases ( ); Q1 2025 noted a significant jump in interest expense and rising operating expenses impacting margins ( ); Q2 2025 explained increased financing costs and noted operating expenses rising due to RCA ( )

    Q3 2025 reported increased net interest expense related to the RCA debt issuance and higher operating expenses driven by the acquisition integration ( )

    Persistent cost pressures and the challenge of managing increased debt financing remain consistent, underscoring the need for efficiency initiatives as acquisitions mature

    Diminishing Emphasis on COVID-19 Impact

    Q4 2024 referenced COVID-19 related headwinds and adjustments in gross margins ( ); Q1 2025 discussed reduced contributions from COVID-19 vaccines and therapies, with diminishing headwinds ( ); Q2 2025 noted a smaller-than-expected COVID headwind with a reduced impact on EPS ( )

    Q3 2025 mentioned a reduced COVID headwind contributing to strong performance, with less emphasis on COVID impacts overall ( )

    There is a clear trend of COVID-19 impacts receding in importance as a headwind, with diminishing effects on margins and operating income across periods

    1. Growth Guidance
      Q: What drives next-year growth?
      A: Management expects fiscal 2026 to benefit from RCA integration, a controlled impact from the oncology loss, and improving utilization trends, supporting organic operating income growth of 5%-8% and EPS growth of 8%-12%.

    2. US Segment Performance
      Q: Why is US revenue moderating while margins improve?
      A: They attributed the modest top‐line pullback to slower GLP‑1 growth, biosimilar influences, and the loss of a low-margin high-revenue customer, even as specialty sales and operational efficiencies drove operating income up by 29%.

    3. GLP‑1 Dynamics
      Q: How do GLP‑1 trends affect profitability?
      A: GLP‑1 products continue driving strong top-line growth but remain only minimally profitable. Management noted that a slowdown or increased competition will likely normalize fees without significantly hurting overall margins.

    4. RCA Integration
      Q: How is RCA performing post-acquisition?
      A: The integration of RCA is progressing smoothly with a strong cultural fit and positive physician feedback, which is enhancing their specialty distribution capabilities.

    5. Earnings Acceleration
      Q: What explains the faster US earnings growth?
      A: The acceleration from 23% to 29% in US operating income is largely due to robust core performance, the new contribution from RCA, and reduced COVID-related headwinds compared to prior periods.

    6. Tariff Impacts
      Q: Do tariffs affect branded and generic drugs differently?
      A: Management observed that tariff-related price increases were in line with expectations, with no material impact on their operations or sourcing practices.

    7. International Visibility
      Q: What is the lead time for international project bookings?
      A: While the sales cycles vary by project size and type, management maintains good visibility on future growth with clear insight into booking trends despite variable lead times.

    Research analysts covering Cencora.