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Mark Enyedy

About Mark Enyedy

Mark Enyedy is a non-employee director of Charles River Laboratories (CRL), appointed on May 20, 2025, and designated to the Corporate Governance & Nominating Committee and the Strategic Planning & Capital Allocation Committee (SPCAC). He brings nearly three decades of biotechnology general management, business development, and legal experience, including service as CEO of ImmunoGen (2016–2024), EVP & Head of Corporate Development at Shire, CEO/director of Proteostasis, and senior operating roles at Genzyme; he holds a J.D. from Harvard Law School and a B.S. from Northeastern University .

Past Roles

OrganizationRoleTenureCommittees/Impact
ImmunoGenPresident & CEO2016–2024Led company through AbbVie acquisition in 2024; significant capital markets and M&A execution
Shire plcEVP & Head of Corporate DevelopmentNot disclosedLed strategy, M&A, corporate planning; commercial oversight for pre-Phase 3 portfolio
Proteostasis TherapeuticsCEO & DirectorNot disclosedLed operations and governance as public-company CEO
Genzyme CorporationPresident, transplant/oncology/MS divisions; various roles15 yearsBuilt therapeutic franchises; senior P&L responsibility
Palmer & Dodge (law firm)AssociateNot disclosedLegal training and early career foundation

External Roles

OrganizationRoleTenureNotes
BioMarinDirectorCurrentPublic company board service
ImmunoGenDirectorPriorServed during CEO tenure
Ergomed plcDirectorPriorPublic company board service
LogicBio TherapeuticsDirectorPriorPublic company board service
Akebia TherapeuticsDirectorPriorPublic company board service
Fate TherapeuticsDirectorPriorPublic company board service
Keryx BiopharmaceuticalsDirectorPriorPublic company board service
American Cancer Society (Eastern New England)BoardPriorNon-profit governance
Biotechnology Innovation OrganizationBoardPriorIndustry association governance

Board Governance

  • Committee assignments: Enyedy was appointed to the Corporate Governance & Nominating Committee (CGNC) and SPCAC; SPCAC includes Barg, Enyedy, and Graves (Chair) .
  • Board composition and independence: After the May 2025 appointments, CRL’s Board consists of eleven directors, nine of whom are independent; Martin Mackay is Lead Independent Director; Nancy Andrews chairs CGNC; Reshema Kemps‑Polanco chairs Compensation; Virginia Wilson chairs Audit .
  • CGNC responsibilities include director nominations, director compensation oversight, governance guidelines, ESG oversight, and shareholder engagement; CGNC met two times in 2024 (three times in 2023; four times in 2022) .
  • Compensation Committee responsibilities include CEO/executive pay oversight, program design, risk assessment, and administering clawbacks; it met four times in 2024 .
  • Voting & resignation policy: Majority voting in uncontested elections with mandatory resignation if a nominee fails to receive a majority; directors serve until the next annual meeting .
  • Attendance: Expectation of attendance; all directors attended over 75% of meetings in 2024 (Enyedy joined in 2025) .

Fixed Compensation

ComponentAmountApplicability to EnyedySource
Annual base cash retainer$65,000Pro‑rated for 2025 service; directors may elect RSUs in lieu of cash
Audit Committee membership fee$5,000Not applicable (Enyedy is not on Audit)
Lead Independent Director fee$45,000Not applicable (Mackay is Lead)
Chair fees (committee chairs)$20,000 for CGNC/Finance/RAUC/STC/SPCAC; $25,000 for AuditNot applicable (Enyedy is not a chair)
Meeting feesNoneNot applicable (no per‑meeting fees)
Expense reimbursementReasonable expenses reimbursedApplicable
  • Directors can elect to receive cash retainers as equivalent‑value RSUs; Non‑Employee Directors’ Deferral Plan allows RSU deferral up to five years or until retirement .
  • Annual director compensation cap: $800,000 per year (equity grant date value plus cash), excluding initial director awards (up to $600,000) .

Performance Compensation

Equity ElementStandard ValueForm & MixTimingNotes
Initial equity grant~$255,50050% RSUs / 50% stock optionsFirst day of month following initial appointmentPro‑rated based on months remaining in board term
Annual equity grant~$255,50050% RSUs / 50% stock optionsAfter each annual meetingStandard annual award for unaffiliated non‑employee directors
  • No performance metrics or PSUs disclosed for director equity awards; grants are RSUs and options valued per ASC 718/Black‑Scholes .

Other Directorships & Interlocks

RelationshipDetailPotential Interlock/Conflict Consideration
Elliott Cooperation AgreementEnyedy is an “Investor Designated Director”; Company will appoint at least one Investor Designated Director to CGNC, Compensation, and SPCACBoard permits Investor Designated Directors to communicate with Elliott subject to fiduciary and confidentiality obligations; standstill/voting commitments apply to Elliott
Related‑party transactionsCompany states no transactions requiring Item 404(a) disclosure for the Cooperation Agreement DirectorsReduces near‑term related‑party risk; continue monitoring for client/supplier overlaps with BioMarin or other boards

Expertise & Qualifications

  • Biotech CEO experience (ImmunoGen), strategic M&A/capital markets leadership, and corporate development expertise (Shire); deep operating experience at Genzyme across multiple therapeutic areas .
  • Legal training and governance experience; currently serves on BioMarin’s board; prior board service across multiple public biopharma companies .
  • Academic credentials: J.D., Harvard Law School; B.S., Northeastern University .

Equity Ownership

PolicyRequirementCompliance WindowNotes
Director stock ownership guidelineMinimum value of vested Company stock equal to 5x annual cash retainer5 years from election to complyDeferral plan allows RSUs to be deferred up to five years or until retirement
  • As a May 2025 appointee, Enyedy falls under the 5‑year window; specific beneficial ownership amounts were not disclosed in the 2025 proxy/8‑Ks .

Governance Assessment

  • Positives: Fresh independent perspectives added to Board; seasoned operator with CEO experience; assigned to CGNC and SPCAC where his deal and capital allocation expertise are relevant; strong governance infrastructure (majority voting; ownership guidelines; independent committee chairs; clawback policy); compensation consultant independence affirmed (Pay Governance) .
  • Watch items/RED FLAGS: Activist involvement via Cooperation Agreement and rights to replace Investor Designated Directors; permitted communications with Elliott could create information‑flow sensitivities; confidentiality carve‑outs exist (particularly for the Investor Director), requiring rigorous adherence to fiduciary duties and Company Policies .
  • Structural mitigants: Standstill/voting commitments constrain Elliott’s tactics during the Cooperation Period; Company Policies apply equally to Investor Designated Directors; no Item 404(a) related‑party transactions for new directors reported .

Say‑on‑Pay & Shareholder Feedback

Proposal (May 20, 2025)ForAgainstAbstainBroker Non‑Votes
Advisory vote on executive compensation40,218,870 1,432,240 102,252 2,209,405
  • Director elections: Seven directors were elected; subsequent Board appointments included Enyedy to fill one of four vacancies (not standing for election at the meeting) .
  • PETA shareholder proposal did not pass (For: 3,457,547; Against: 38,051,509; Abstain: 244,306; Broker Non‑Votes: 2,209,405) .

Director Compensation (Structure Overview)

ElementCashEquityDeferral/Notes
Annual compensation$65,000 base; committee chair premiums; Audit membership $5,000; no meeting fees Annual ~$255,500 (50% RSUs/50% options) Cash may be taken as RSUs; RSUs deferrable up to 5 years/retirement
Initial appointment grantPro‑rated retainer post‑appointment ~$255,500 pro‑rated; issued first day of month after appointment Grant date value under ASC 718; options valued via Black‑Scholes
Annual capn/aCombined cash + equity ≤ $800,000/year; initial director award ≤ $600,000Governance cap under Amended & Restated 2018 Incentive Plan

Related Party & Conflicts

  • No transactions since the beginning of the prior fiscal year, nor currently proposed, requiring Item 404(a) disclosure for the Cooperation Agreement Directors .
  • Cooperation Agreement prohibits Elliott from compensating Investor Designated Directors in connection with their Board service (other than ordinary‑course employment arrangements for the Investor Director, not applicable to Enyedy) .
  • Company Policies apply to confidentiality, trading, conflicts, and resignation policies; Investor Designated Directors may communicate with Elliott subject to fiduciary duties and confidentiality requirements .

Committee Activity Context

Committee2024 MeetingsResponsibilities (selected)
Compensation Committee4 Executive pay oversight; program design; risk and clawback administration
Corporate Governance & Nominating Committee2 Nominee vetting; director compensation oversight; governance guidelines; ESG oversight; shareholder engagement

Overall, Enyedy’s appointment adds experienced operator and dealmaker expertise to governance and strategic oversight. The activist framework introduces engagement and information‑sharing dynamics that require disciplined compliance with Company Policies and fiduciary duties, mitigated by standstill/voting commitments and independent committee leadership .