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CHARLES RIVER LABORATORIES INTERNATIONAL (CRL)

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Earnings summaries and quarterly performance for CHARLES RIVER LABORATORIES INTERNATIONAL.

Research analysts who have asked questions during CHARLES RIVER LABORATORIES INTERNATIONAL earnings calls.

CW

Casey Woodring

JPMorgan Chase & Co.

4 questions for CRL

Also covers: A, BLLN, HOLX +10 more
DW

David Windley

Jefferies Financial Group Inc.

4 questions for CRL

Also covers: CERT, CNC, CTLT +14 more
Elizabeth Anderson

Elizabeth Anderson

Evercore ISI

4 questions for CRL

Also covers: AGL, ALGN, CAH +23 more
MS

Max Smock

William Blair & Company

4 questions for CRL

Also covers: CDMO, CERT, CTLT +7 more
Michael Ryskin

Michael Ryskin

Bank of America Merrill Lynch

4 questions for CRL

Also covers: A, ALGN, AVTR +28 more
Patrick Donnelly

Patrick Donnelly

Citi

4 questions for CRL

Also covers: A, AVTR, BIO +21 more
CR

Charles Rhyee

TD Cowen

3 questions for CRL

Also covers: AMWL, BTSG, CAH +18 more
EC

Eric Coldwell

Robert W. Baird & Co.

3 questions for CRL

Also covers: AHCO, CAH, COR +9 more
JB

Justin Bowers

Deutsche Bank AG

3 questions for CRL

Also covers: AMED, CON, CTLT +9 more
TS

Tejas Savant

Morgan Stanley

3 questions for CRL

Also covers: ADPT, AKYA, AVTR +19 more
AH

Ann Hynes

Mizuho Financial Group

2 questions for CRL

Also covers: ARDT, BTSG, CI +17 more
Joshua Waldman

Joshua Waldman

Cleveland Research Company

2 questions for CRL

Also covers: A, BRKR, ICLR +1 more
MS

Matthew Sykes

Goldman Sachs Group Inc.

2 questions for CRL

Also covers: A, ADPT, AVTR +21 more
AK

Anna Kruszenski

Barclays

1 question for CRL

Also covers: CERT
DL

Daniel Leonard

Stifel Financial Corp.

1 question for CRL

Also covers: A, AVTR, BIO +15 more
JJ

Jacob Johnson

Stephens Inc.

1 question for CRL

Also covers: AZTA, CDMO, CDXS +11 more
KC

Kyle Cruise

UBS

1 question for CRL

Also covers: WST
Luke Sergott

Luke Sergott

Barclays

1 question for CRL

Also covers: A, AVTR, BRKR +19 more
MS

Matt Sykes

Goldman Sachs Group, Inc.

1 question for CRL

Also covers: CTKB, MRVI, NTRA +4 more

Recent press releases and 8-K filings for CRL.

Charles River Labs outlines strategic divestitures and NAMs investment
CRL
M&A
New Projects/Investments
Demand Weakening
  • Sequential improvement in book-to-bill since Q3, driven by an uptick in biotech funding (second-best month ever) and stable pharma demand under long-term contracts.
  • Plans to divest ~7% of non-core revenue, with proceeds targeted for M&A in lab services/bioanalysis, NAMs technologies, and potential China expansion.
  • Investing in lab services growth and targeting $70 million of efficiency savings through labor optimization, procurement improvements, offshoring, and automation.
  • Expanding NAMs portfolio via internal initiatives and targeted acquisitions, while leveraging FDA guidance easing long-term NHP requirements for monoclonal antibody studies to accelerate discovery tools.
  • Upgraded CDMO facilities now support additional cell- and gene-therapy capacity, and the microbial LAL testing business remains a high-margin, IP-protected cornerstone.
Dec 3, 2025, 3:00 PM
Charles River outlines strategic priorities at Evercore HealthCONx conference
CRL
Demand Weakening
M&A
Hiring
  • Book-to-bill has improved sequentially since the start of Q3, supported by stable pharma demand via multi-year contracts and a rebound in biotech funding, with October as the second-best funding month ever.
  • Lab services (DSA) sees targeted hiring and investments in procurement efficiency, offshoring, and automation to drive $70 M of margin improvement in 2026.
  • Non-core asset divestiture (~7% of revenue) is underway, with proceeds earmarked for M&A, debt reduction, or share buybacks.
  • NAMs strategy with $200 M in current revenue focuses on acquiring practical non-animal in vitro technologies for discovery; minimal near-term impact on safety testing beyond monoclonal antibodies.
  • Geographic expansion considerations include re-entering the China market and bolstering bioanalysis and lab services to capitalize on local innovation and cost-sensitive workflows.
Dec 3, 2025, 3:00 PM
Charles River highlights improving book-to-bill, divestiture and investment plans
CRL
Demand Weakening
M&A
  • Sequential improvement in book-to-bill since the start of Q3 2025, buoyed by second-best monthly biotech funding ever and stable pharma demand, although biotech remains the primary headwind tied to capital access.
  • Plans to divest ~7% of revenue in non-core assets following a deep portfolio review, with proceeds targeted for strategic M&A, debt reduction, or share repurchases.
  • Accelerating lab services (bioanalysis) growth through organic hiring and potential M&A to expand large-molecule bioanalysis and high-throughput clinical sample capabilities.
  • Evaluating non-animal methods (NAMs) and geographic expansion (Europe, China) via dedicated internal and board committees, expecting NAMs to drive discovery enhancements but minimal near-term impact on safety testing.
  • Manufacturing segment (CDMO) shows upgraded facilities and regulatory compliance, yet faces demand softness in clinical manufacturing; microbial (LAL) testing remains a high-margin, stable business.
Dec 3, 2025, 3:00 PM
Charles River Laboratories discusses Q3 demand trends and strategic initiatives
CRL
Demand Weakening
Share Buyback
M&A
  • In Q3, CRL’s net book-to-bill was 0.82, flat sequentially, driven by a summer biotech lull but with improving month-over-month biotech bookings and stable pharma demand.
  • Pricing in the safety assessment segment has stabilized since 2023/24, with no headwinds from price/mix and strategic discounts used to maintain market share amid softer demand.
  • Discovery services (≈10% of DSA) remain soft due to constrained biotech funding, but CRL expects a rebound as funding improves and clients progress toward toxicology studies.
  • Non-human primate (NHP) supply is stable after acquiring the Novaprim farm and SEC/DOJ clearances, enhancing internal capacity, cost competitiveness, and pricing flexibility for safety studies.
  • CRL added $70 M of annualized cost-saving initiatives by 2026 through site consolidations, G&A efficiencies, procurement, and digital automation; management also plans potential share buybacks and targeted acquisitions, especially in bioanalytical services.
Nov 18, 2025, 11:30 AM
Charles River Laboratories outlines demand trends and strategic initiatives
CRL
Demand Weakening
Share Buyback
M&A
  • Q3 net book-to-bill was 0.82, flat with Q2; biotech bookings have improved month-over-month while pharma demand remains stable, and pricing has stayed steady with a price-mix tailwind
  • Holds roughly 30% market share in safety assessment; smaller competitors are discounting for utilization but CRL competes on regulatory compliance, client centricity, and quality
  • Discovery services account for 10% of the DSA segment and have softened amid biotech funding constraints but are expected to rebound as funding improves
  • Announced an additional $70 million of annualized cost savings by 2026 through site consolidations, G&A efficiencies, procurement initiatives, and digital automation; proceeds may support share repurchases or targeted acquisitions in bioanalysis and China
  • Non-human primate supply is now stable after a Q4 shipment was pulled into Q3; Mauritius and Asian sources are secured, and Novaprim farm contracts step down end-2026 to bolster internal study competitiveness
Nov 18, 2025, 11:30 AM
Charles River Q3 2025 results and strategic review
CRL
Earnings
Guidance Update
Share Buyback
  • Revenue of $1.0 B in Q3 2025, down 0.5% YoY (organic –1.6%), with operating margin at 19.7% and EPS of $2.43, a 6.2% decline.
  • Full-year 2025 guidance narrowed: organic revenue now expected to decline 1.5%–2.5%, with non-GAAP EPS at $10.10–$10.30.
  • Board’s strategic review targets divestiture of ~7% of 2025 revenue to generate $0.30 annualized EPS accretion, aiming for completion by mid-2026.
  • Stock repurchase authorization refreshed at $1.0 B; Q3 free cash flow was $178.2 M, with full-year FCF now expected at $470–$500 M.
Nov 5, 2025, 2:00 PM
Charles River Laboratories reports Q3 2025 results
CRL
Earnings
Guidance Update
CFO Change
  • Total revenue was down 0.5% reported and 1.6% organic; GAAP EPS of $1.10 (–17.3%) and non-GAAP EPS of $2.43 (–6.2%) in 3Q25.
  • 2025 guidance narrowed: forecasted reported revenue decline of 1.5%–0.5%, organic decline of 2.5%–1.5%, and non-GAAP EPS of $10.10–$10.30.
  • Generated $178.2 M in free cash flow in 3Q25 and, in October, the Board authorized a new $1.0 B share repurchase program.
  • Michael G. Knell appointed interim CFO to lead the Finance organization until a permanent successor is named.
Nov 5, 2025, 2:00 PM
Charles River Laboratories reports Q3 2025 results and strategic update
CRL
Earnings
Guidance Update
Share Buyback
  • The board’s strategic review aims to divest ~7% of 2025 revenue in underperforming/non-core assets by mid-2026, targeting $0.30 in annualized non-GAAP EPS accretion.
  • Q3 2025 revenue was $1.0 billion (-0.5% YoY; ‑1.6% organic), operating margin 19.7%, and non-GAAP EPS $2.43 (-6.2% YoY).
  • Full-year 2025 outlook narrowed to organic revenue down 1.5%–2.5% and non-GAAP EPS of $10.10–$10.30 at the top of the prior range.
  • Board authorized a new $1 billion share repurchase program; Q3 free cash flow was $178.2 million, with full-year FCF raised to $470–$500 million.
Nov 5, 2025, 2:00 PM
Charles River Laboratories reports Q3 2025 results
CRL
Earnings
Guidance Update
Share Buyback
  • Board supports strategic review to focus on core scientific portfolio, divest ~7% of 2025 revenue in underperforming assets (≈$0.30 annualized non-GAAP EPS accretion), $225 M cost savings by 2026 plus $70 M incremental savings; new $1 B stock buyback authorization ($450.7 M repurchased since Aug 2024)
  • Q3 revenue $1.0 B (−0.5% YoY; −1.6% organic); DSA revenue $600.7 M (−3.1% organic) with $1.80 B backlog and 0.82 book-to-bill (net bookings $494 M); RMS margin 25% (+400 bps); Manufacturing revenue $190.7 M (−5.1% organic) with high single-digit growth in microbial solutions
  • Narrowed FY2025 outlook: organic revenue down 1.5–2.5% (DSA −2.5–3.5%, Manufacturing flat to slightly negative, RMS stable); non-GAAP EPS at top of $10.10–10.30; operating margin flat to −30 bps
  • Q3 free cash flow $178.2 M; FY FCF raised to $470–500 M; CapEx ~$200 M (5% of revenue); debt $2.2 B with 2.1x net leverage; $1 B remaining buyback capacity
Nov 5, 2025, 2:00 PM
Charles River Labs reports Q3 2025 results
CRL
Earnings
Guidance Update
M&A
  • Board-backed strategic review focuses on core markets, divesting ~7% of 2025 revenue in underperforming/non-core assets by mid-2026, targeting annualized non-GAAP EPS accretion of ≥$0.30.
  • Q3 EPS of $2.43, down 6.2% YoY; narrowed 2025 organic revenue decline guidance to 1.5%–2.5% and non-GAAP EPS to $10.10–$10.30.
  • DSA segment revenue of $600.7 M (–3.1% organic YoY) with stable 0.82 book-to-bill and backlog of $1.80 B; RMS operating margin up to 25%; manufacturing revenue $190.7 M (–5.1% organic).
  • Q3 free cash flow of $178.2 M; raised full-year free cash flow outlook to $470 M–$500 M; CapEx lowered to ~$200 M (~5% of revenue).
Nov 5, 2025, 2:00 PM

Quarterly earnings call transcripts for CHARLES RIVER LABORATORIES INTERNATIONAL.