Cryoport - Earnings Call - Q1 2025
May 7, 2025
Executive Summary
- Q1 2025 revenue from continuing operations was $41.0M, up 10.1% year over year; total gross margin expanded to 45.4% and adjusted EBITDA improved to -$2.8M from -$6.7M YoY.
- Revenue beat S&P Global consensus by ~2.3% ($41.0M vs. $40.1M), while EPS missed (Primary EPS actual -$0.384 vs. -$0.258 est.); management reiterated FY25 continuing-ops revenue guidance of $165–$172M; bold catalysts: service margin expansion and DHL strategic partnership execution.
- Life Sciences Services led with 17% YoY growth (56% of revenue); commercial Cell & Gene therapy revenue rose 33% YoY to $7.2M; total supported clinical trials reached 711, with 79 in Phase 3.
- Strategic partnership with DHL and planned CRYOPDP divestiture positions CYRX to strengthen APAC/EMEA reach and sharpen focus on regenerative medicine; transaction expected to close in Q2/Q3 2025.
What Went Well and What Went Wrong
What Went Well
- Services-led growth and margin expansion: Life Sciences Services revenue +17% YoY to $22.9M and Services gross margin rose to 47.9% (from 43.5%).
- Commercial CGT momentum: commercial revenue +33% YoY to $7.2M; 19 commercial therapies supported and 711 active trials as of March 31, 2025.
- Strategic DHL partnership: management emphasized global reach and capital infusion; “This arrangement will enhance our operational reach… and reshape our competitive profile” (CEO).
What Went Wrong
- EPS below Street: Primary EPS actual -$0.384 vs. -$0.258 est.; despite improved gross margin and lower opex, adjusted EBITDA remained negative due to ramp investments (e.g., IntegriCell).
- Continued GAAP net loss: Q1 net loss was $12.0M (incl. discontinued ops) and net loss per share was -$0.28; Services ramp and newer initiatives still weighed on profitability.
- Tariff headwinds emerging: management flagged early impacts on aluminum; mitigation via supply chain diversification and surcharges, potentially adding near-term friction even if margin-protective.
Transcript
Operator (participant)
Good afternoon, and welcome to Cryoport First Quarter 2025 earnings call. All participants will start in a listen-only mode. After the speaker's presentation, there will be a question-and-answer session, and instructions will be provided at that time. As a reminder, this call is being recorded. I will now turn the call over to your host, Todd Fromer from KCSA Strategic Communications. Please go ahead, sir.
Todd Fromer (President)
Thank you. Before we begin today, I would like to remind everyone that this conference call contains certain forward-looking statements. All statements that address our operating performance, events, or developments that we expect or anticipate occurring in the future are forward-looking statements. These forward-looking statements are based on management's beliefs and assumptions, and not on information currently available to our management team. Our management team believes that these forward-looking statements are reasonable as and when made. However, you should not place undue reliance on any such forward-looking statements because such statements speak only as of the date when made. We do not undertake any obligation to publicly update or revise any forward-looking statements, whether as a result of new information or future events or otherwise, except as required by law.
In addition, forward-looking statements are subject to certain risks and uncertainties that could cause actual results, events, and developments to differ materially from our historical experience and our present expectations or projections. These risks and uncertainties include, but are not limited to, those described in Item 1A, Risk Factors, and elsewhere in our annual report on Form 10-K to be filed with the U.S. Securities and Exchange Commission, and those described from time to time in other reports which we file with the U.S. Securities and Exchange Commission. It is now my pleasure to turn the call over to Mr. Jerrell Shelton, Chief Executive Officer of Cryoport. Jerry, the floor is yours.
Jerrell Shelton (CEO)
Thank you, Todd. Good afternoon, ladies and gentlemen. With us this afternoon is our Chief Financial Officer, Robert Stefanovich, our Chief Scientific Officer, Dr. Mark Sawicki, and our Vice President of Corporate Development and Investor Relations, Thomas Heinzen. As a reminder, we have uploaded our First Quarter 2025 and review document to our website. It can be found on the main page of the Cryoport website. This document provides a review of our financial and operational performance and a general business outlook. If you've not had a chance to read it, I would encourage you to go to our website and download it.
Before I review our results, I would like to highlight that due to our recently announced strategic partnership with DHL and the related sale of CryoPDP to DHL, CryoPDP's financials, which were previously a part of Cryoport's Life Sciences Services reportable segment, are now presented as discontinued operations. Accordingly, we have provided quarterly historical information on this basis for 2024 in our First Quarter 2025 and review document. This information is intended to support financial modeling efforts for those needing this information. Please note that unless indicated, all revenue figures discussed today will refer to continuing operations. This includes our Fiscal Year 2025 revenue guidance first shared alongside our DHL transaction announcement. Now I'll provide a brief update on our business, and then we will take your questions.
Cryoport had a solid start to the year with $41 million of revenue from continuing operations for the first quarter, which represented 10% year-over-year growth and helped drive meaningful adjusted EBITDA improvement. Three things that excited us about the first quarter were, first, client engagement and life sciences services grew substantially, highlighting a new momentum in our business. Second, order patterns for our life sciences products continued to show signs of stabilization. Finally, our strategic partnership with DHL. Life sciences services revenue in total increased 17% year-over-year, which included our support of commercial cell and gene therapies, which grew 33% over last year. Life sciences services now account for 56% of total revenue, and it continues to be driven by the increasing development and commercialization of cell and gene therapies, which we believe will persist even in the current economic environment.
As of March 31, Cryoport supported 19 commercial therapies and 711 clinical trials, representing approximately 70% of cell and gene therapy trials. Subsequent to the quarter end, a new therapy from our customer Aveeno Therapeutics was approved, bringing our total commercial therapies supported to 20. In the first quarter, six BLA-MMAA filings occurred. Three filings were for new therapies, and three filings were for geographic expansion. Additionally, Bristol-Myers Squibb received a supplemental approval from the European Commission to expand the label of Breonzi as a third-line treatment for relapsed or refractory follicular lymphoma. For the remainder of 2025, we anticipate up to an additional 17 application filings for therapy approvals and an additional four approvals for label or geographic expansions or moves to earlier lines of treatment, all of which give us further confidence in our growth forecast.
Our life sciences products business continues to show further signs of demand stabilization and grew 2% year-over-year. We are continuing to expand our product portfolio to capture new revenue streams with innovative products, including the MVE High Efficiency 800C, which was released in the first quarter and meets the needs of facilities that have limited space yet require high capacity and security. Another key milestone this quarter was the announcement of our strategic partnership with DHL Group. As a part of our strategic partnership, DHL acquired Cryoport DP for an enterprise value of $195 million, which we expect to close in the second or third quarter. We think this arrangement will enhance our positioning in Asia-Pacific and Europe, Middle East and Africa and reshape our competitive profile within the industry by leveraging the global scale and capabilities of our new strategic partner, DHL.
Our strategic shift is responsive to market changes driven by the evolution and progress of our industry and provides us with a strong infusion of capital, a substantial return on investment, and a strategic partnership that enables us to sharpen our focus on our core of the life sciences service offerings directed toward the rapidly growing regenerative medicine space. Consequently, we're confident in our organic growth outlook for the full year and are confirming our revenue guidance for Fiscal Year 2025 in the range of $165 million-$172 million, which at the midpoint represents a 7.5% growth relative to Fiscal Year 2024. Before we begin to take your questions, I want to briefly talk about global tariffs.
In situations where tariffs may impact our business, such as potential increases in cost of raw materials such as electronics, aluminum, and stainless steel, we have already taken steps to diversify our supply chain. In situations where we cannot mitigate tariff charges, we will implement surcharges. We have successfully taken a similar approach in the past. For example, during the supply chain challenges experienced during COVID, we were able to maintain solid financial margins. To be clear, we are beginning to see impact from tariffs on aluminum, and we will pass those costs through a surcharge as appropriate. We feel confident in our ability to manage potential future cost increases due to tariffs. More broadly, we do not expect tariffs to impact our core support of clinical trials or commercial therapies. Of course, we will continue to assess the situation and keep you updated as more information becomes available.
In closing, we made meaningful progress during the first quarter in revenue generation, operational improvements, and with the DHL strategic partnership. With this progress to accelerate our growth, we remain focused on supporting the increasing number of commercial regenerative medicine products and the rollout around the world. We are also advancing our key initiatives such as IntegraCell Cryopreservation Solution, our Global Supply Chain Center network, and introducing new services and products in order to better serve our clients and open up new revenue streams. We remain confident that the actions we have underway and our momentum will lead us to a return to positive adjusted EBITDA during 2025. This concludes my prepared remarks, so now I will ask the operator to open the lines for your questions.
Operator (participant)
Thank you. Ladies and gentlemen, we will now begin the question-and-answer session. Should you have a question, please press the star followed by the number one on your touch-tone phone, and you will hear a prompt that your hand has been raised. Should you wish to decline from the polling process, please press the star followed by the number two. If you use the speakerphone, please lift the handset before pressing any keys. One moment, please, for your first question. Your first question comes from Kyle Cruz with UBS. Please go ahead.
Kyle Crews (Equity Research Associate)
Hey, thank you for taking the questions here. Could you give us a brief update on the launch of IntegraCell and how client adoption is going there? Could you touch upon CGT trial growth? Specifically, I think I calculated around high single-digit growth there. Could you speak to the health of the market given some of the negative news flow that we're hearing? Thank you.
Jerrell Shelton (CEO)
Yeah, first of all, I'll speak to the market, and then I'm going to turn it to Dr. Sawicki, who can answer your questions about the market and especially IntegraCell and our advancements. We see the market very positively. We see all those things that I mentioned to you in my opening remarks. We see commercial revenue continuing to ramp with the growth of a number of commercial therapies continuing to grow, the growth in the addressable market of our customers' therapies, and the growth in the number of clinical trials we support. We're bullish, and we are well on our way to building our company to that profitable growth bridge that I've mentioned several times. Mark, would you take the rest of the questions?
Mark Sawicki (Chief Scientific Officer)
Sure, happy to do so. Yeah, just to further with Jerry, you know 2024 was a decent year from a financing standpoint. Cell and gene therapy space grew about 30% from a financing standpoint, which is obviously stabilizing the market and providing a significant fund for our companies to continue to progress their clinical and commercial portfolio. Commercial therapies are continuing to progress nicely. We're up to 20 approved therapies that we support at this point in time, and there continues to be a robust pipeline overall, which is very exciting. We anticipate, as Jerry had said in his opening remarks, up to 17 additional filings this year, potentially another four therapy approvals and four label expansions. That's a very robust year, and we'll be consistent with the record year that we saw last year from an approval standpoint. It continues to be very nice and robust.
Turning to IntegraCell, IntegraCell is progressing very, very nicely. As we had mentioned previously, both facilities in Houston, Texas, and Leeds, Belgium are open, and we also have and already have multiple commercial contracts and are currently onboarding multiple programs into those facilities. It is progressing nicely.
Kyle Crews (Equity Research Associate)
Great, thank you.
Operator (participant)
Thank you. The next question comes from Richard Baldry with Roth Capital. Please go ahead.
Richard Baldry (Managing Director and Senior Analyst)
For contingent consideration, it changes that. Is there a reason that isn't backed out as sort of a one-time event? Because I think if my math is right, without that, it'd be moderately positive on adjusted EBITDA.
Jerrell Shelton (CEO)
Sorry, Rich, we were cut off from you. Can you please restate your question?
Richard Baldry (Managing Director and Senior Analyst)
When I look at the adjusted EBITDA loss, it's sort of a minor amount, but it's including a drag, it looks like, from contingent consideration. I'm just curious why that, as a one-time event, wouldn't have been backed out of that number. Because if my math is right, it looks like you'd be positive EBITDA without that drag.
Jerrell Shelton (CEO)
No, we did back it out. It goes the other way. We had a contingent consideration at year-end that we released in Q1 related to one of the acquisitions. We did back that out. Having said that, obviously, the adjusted EBITDA did improve significantly over Q1 of last year based on the initiatives that we took in 2024.
Richard Baldry (Managing Director and Senior Analyst)
Got it. Post the divestiture, whenever it closes, you'd have a pretty disproportionate now amount of net cash versus your market cap. Can you talk about what you think the appropriate steps to bolster shareholder value would be given that very large cash reserve versus pretty modest adjusted EBITDA losses?
Jerrell Shelton (CEO)
Yeah, Rich, we will be prudent in the way we allocate that cash, the use of that cash, and so forth. Of course, we're living in some times that have a fair amount of uncertainty in them, but we'll be prudent, we'll be opportunistic, and we'll be careful about the way we allocate that cash. One of the things we will consider is the fact that our stock is highly, highly undervalued, and we certainly will. We have an authorization for stock buyback, and so that will be a consideration at the time we look at the uses of the cash.
Richard Baldry (Managing Director and Senior Analyst)
Great, thank you.
Operator (participant)
Thank you. The next question comes from Punet Soda with Leerink Partners. Please go ahead.
Michael Clifford (Senior Managing Director)
Hi, you have Michael on for Punet. Thank you for taking my question. My first one has to do with the service growth margins. I'm getting about like a 500 basis point year-over-year expansion. So I'm curious what's driving that growth and also if we should expect a similar year-over-year expansion in the balance of the year.
Jerrell Shelton (CEO)
Yeah, if you look at the gross margin for the company and services and products, you're absolutely right. We saw a significant increase in the services gross margin for Q1 year-over-year. We do expect to see more leverage from our core services in the cell and gene therapy space for our services. Over time, you will see an expansion of the gross margin for the services side. We do, however, also have a couple of newer initiatives that will still depress somewhat that growth in gross margins, such as IntegraCell, that is just starting to ramp. We do expect strong gross margins to continue throughout 2025. Certainly, as you look into 2026, 2027, we expect margin improvements beyond what you're seeing today.
Got it. On the clinical trial starts, I was wondering if you could offer any color about how small versus large pharma is performing. We've heard comments from the broader tool space that midcaps have been kind of pulling back and large pharma has been a bit healthier. I was wondering what your view on the market is.
Mark, why don't you take that?
Mark Sawicki (Chief Scientific Officer)
Sure. Yeah, we've seen it be very balanced. We're seeing contribution on the ads from both the biotech as well as the large pharma environment. What we're seeing overall is those biotechs that have promising pipelines are seeing additional interest from large pharma where they're continuing to resource and put money into and purchase licensing agreements for a lot of these product lines. It is maintaining a robust flow from both.
Jerrell Shelton (CEO)
Maybe to add into that, in Q1, we did have 32 adds and 22 removes from our, so we reported a net up 10, but it was a strong amount of adds in Q1 for our clinical trials.
Mark Sawicki (Chief Scientific Officer)
Yeah, very strong. Correct. Yep, correct.
Michael Clifford (Senior Managing Director)
Thank you.
Operator (participant)
Thank you. The next question comes from David Larsen with BTIG. Please go ahead.
David Larsen (Equity Research Analyst)
Hi, congratulations on the good quarter. 10% year-over-year revenue growth looks pretty good to me. Jerry, you already mentioned some of this in your prepared comments, but can you talk about just the broader macro environment? How are your clients responding to potential 25% tariffs? There was this executive order for drug pricing signed on April 15th. There's the ongoing impact from the Inflation Reduction Act. IQVIA had a year-over-year decline in their services bookings. The CROs are under pressure. What is the response from your clients and demand, the demand side of your business, if any? Thank you.
Jerrell Shelton (CEO)
David, we really do not have any significant tariff impact on cell and gene therapy. So we are moving along pretty well. And Mark, you may wish to add to that.
Mark Sawicki (Chief Scientific Officer)
Yeah, so the positive thing is the vast majority of those actions that you talked about from a government standpoint are really focused around small molecule and biologic drug product, which has high volume, large revenue streams. The vast majority of the cell and gene therapies out there are for very specific indications, and they are the only product available to address that particular etiology based on the fact that they've already gone through all the alternatives or many of the alternatives. The pressure there is, I think, a lot different. We're not seeing a lot of concern. I'm actually down at ISCT right now, which is the International Society of Cell and Gene Therapy Conference, and the mindset here has been pretty positive. We're not seeing a lot of concern.
Jerrell Shelton (CEO)
David, we're continuing to see the commercial revenues ramp, and we're continuing to, as we forecasted, continue to see commercial therapies maturing and coming to market. We're very optimistic.
David Larsen (Equity Research Analyst)
Okay, so a lot of the source materials come from the United States, so they wouldn't be impacted by tariffs. Is that correct?
Jerrell Shelton (CEO)
Correct. Yeah, David, most of the product, if you will, the therapies, the cells are taken right from the sick patients. The patients are in the same countries where it is, I'll call it, manufactured and then sent back to the patient on the autologous side.
David Larsen (Equity Research Analyst)
Okay, and you also answered this already, but I'm going to ask again. In terms of your own cost of goods, it seems like there's a lot of technology you're working with. You got the dewars, you got the technology on the dewar, all those electronic components. There's transport costs. I heard you say that those tariffs, if they happen, you're going to pass them through to your clients through surcharges. You are not expecting any increase in cost or margin pressure. Is that correct?
Jerrell Shelton (CEO)
Partially correct, David. We have an incredibly able sourcing team, and we've already worked on mitigating tariffs by changing supply chain routing or supply chain sources and so forth. As I mentioned in the opening comments, those that are passed on to us through components or those that we cannot mitigate, we will put into surcharges because we do not think this will be permanent. We think that in surcharges, we can extract at the time that they're not. We will protect our margins. I do not think this is unusual for anyone, so we feel like we have this under control for sure.
David Larsen (Equity Research Analyst)
Okay, one last quick one, please. Product revenue grew year-over-year. Just any color there in terms of ongoing demand? Looks like it's not only bottomed, but it's coming back up. Is that?
Jerrell Shelton (CEO)
Yeah, I mean, the demand did grow 2% in products year-over-year. The revenue, in particular from North America, has improved over the past three quarters. We expect that trend to continue as our products are made in America, and they won't be subject to tariffs. While global markets have been disrupted somewhat, the Americas are showing resilience and incremental revenue growth as they have for the last three quarters, and we predict that'll continue.
David Larsen (Equity Research Analyst)
Okay, I'll hop back in the queue. Looks like a good quarter. Thank you.
Jerrell Shelton (CEO)
Thank you.
Operator (participant)
Thank you. The next question comes from Siddon Nambi with Guggenheim Securities. Please go ahead.
Subbu Nambi (Managing Director)
Thank you for taking my questions. How much does supply chain initiatives actually improve margins? Any chance you could quantify that as well? Will that be a long-term improvement to margins, or is that a more short-term fix?
Jerrell Shelton (CEO)
Yeah, I don't think we can quantify it necessarily in terms of impact on margin. I think the most important part of the surcharges is to ensure that our margins are not negatively impacted by these tariffs. I think the margin improvement is really going to be driven largely by the expansion of our services, leveraging the client base that we have and leveraging the growing number of commercial therapies.
Subbu Nambi (Managing Director)
Thank you for that. One follow-up. Probably the elephant in the room is the new FDA director who seemingly has a more, for lack of a better way of saying, stricter stance to newer modality therapy. Anything that you're messaging to your current shareholders?
Jerrell Shelton (CEO)
That's about the new head of CBER, Subbu, you're asking about?
Subbu Nambi (Managing Director)
Yeah.
Jerrell Shelton (CEO)
The new head of CBER is an accomplished scientist. He may have some conservative views that have been reported and so forth, but he's a conservative scientist. He's quite accomplished. As a scientist, we feel that the data will rule. There may be more stricture in structure and so forth as we move forward, but we're very optimistic about his service and about his qualifications.
Mark Sawicki (Chief Scientific Officer)
The Trump administration has also come out implicitly in favor of cell and gene therapy as a modality. I do think there's an interest there from the administration to see continued progress there.
Subbu Nambi (Managing Director)
Just keep your heads down. This is too sharp, and you still believe in the modality is the messaging here.
Jerrell Shelton (CEO)
Yeah, and at the end of the day, the safety and efficacy of these therapies is being proved out every day. That is the main theme, I think, to keep on your mind, Subbu.
Subbu Nambi (Managing Director)
Thank you, guys. I'll hop back in the queue.
Operator (participant)
Thank you. The next question comes from Tejas Seventh with Morgan Stanley. Please go ahead.
Tejas Savant (VP)
Edmund Non-Pretagius, thank you for the time. Maybe to start off, can you guys share some color on how the traction has been with your new launches in the product side? How has the demand been for HP3 and the new HE800? How much of the demand stabilization can be accredited to these two products?
Jerrell Shelton (CEO)
Mark, would you like to take that question?
Mark Sawicki (Chief Scientific Officer)
Sure. On the HP3, the HP3 has been very, very well received in a market standpoint, and adoption is ongoing as we speak. It'll be rolling into a substantial number of our commercial therapy support mechanisms over the next 12-18 months. That has been extremely positive. What was the other product you were asking about?
Jerrell Shelton (CEO)
That's the HC800 at MVE, Mark, but go ahead, Robert.
Robert Stefanovich (CFO)
Yeah, I just wanted to clarify. The HP3 is related to Cryoport Systems and Cryoport Systems Solution. So that's not related to product revenue. It wouldn't be reflected. If you look at the product revenue, that's specifically related to the MVE suite of freezers and accessories.
Tejas Savant (VP)
Got it.
Jerrell Shelton (CEO)
The second product that you mentioned, that's just being rolled out, so that's too early to talk about at this stage.
Tejas Savant (VP)
Got it. Circling back to one of the earlier questions on IntegraCell, can you guys provide some color on how the onboarding process has been? When can we expect to see some more meaningful revenue contributions from your earlier customers?
Mark Sawicki (Chief Scientific Officer)
Yeah, so the onboarding process has been very smooth. As I had mentioned, we're already under multiple contracts, including top 10 pharma supporting that have asked us to step in and support aspects of their cell and gene therapy portfolio from a standardized cryopreservation standpoint. The process takes a little bit of time because there's a tech transfer process where it has to go through verification, which takes a few quarters. Those are running very, very smoothly, and the feedback has been extremely positive.
Tejas Savant (VP)
Got it. Thank you guys for the time.
Operator (participant)
Thank you. The next. Oh, by the way, once again, should you have a question, please press the star followed by the number one on your touchstone phone, and you will hear a prompt that your hand has been raised. The next question comes from Matt Stanton with Jefferies. Please go ahead.
Matt Stanton (Stock Analyst)
Hey, guys. I wanted to touch quick on the leading indicators. You talked about both orders stabilizing for life science products, but also engagement levels increasing meaningfully for the life science solution side. Any way you can kind of just put a finer point or qualify the order improvement you're seeing or the nature of conversations with customers and potential customers? I think you talked about on the solution side strength, both deeper penetration at existing clients, but also new clients. Just any more kind of flavor you can provide around some of those leading indicators you talked about a little bit earlier. Thank you.
Mark Sawicki (Chief Scientific Officer)
I can comment.
Jerrell Shelton (CEO)
Mark, you want to talk about the.
Mark Sawicki (Chief Scientific Officer)
Yeah, on the service side, I think there's a few things that you can look at, obviously, the traction in the service side of our business. The first is our clinical trial portfolio. The fact that we're now up to 711, we saw a net increase of 10 programs, and a total number of onboarded programs over 30 is a very robust number. I think that demonstrates the health in our service business. We also continue to see very nice diversification as evidenced by the increase in our biostorage and bioservices revenue, which was up 22.5% year-over-year.
Both of those are an indication of, number one, the onboarding of new clients, which seems to be re-accelerating based on the clinical trial acquisition, as well as you see robust growth in our other services, ancillary services like bioservices, which demonstrates a nice diversification of that revenue stream in our existing client portfolio as well as new.
Jerrell Shelton (CEO)
I think one other thing, Matt, to keep in mind is the ecosystem that you're seeing keep building around this industry of the cell and gene therapies and regenerative medicine. You're seeing that with DHL acquiring our CRYOPDP, UPS expanding their healthcare, and the other players like Cardinal Health and Sencora continuing to learn and to turn to the cell and gene space. We're really focused with our strategic pivot on enabling all of those big companies with where they're going.
Matt Stanton (Stock Analyst)
Great. That's helpful, Colin. Maybe one for Robert. Just nice to see the reiteration of the guide given the choppy macro backdrop. I think previously you guys had kind of talked about modest growth on the product side and maybe something like high singles or double-digit growth on the service side. Just given a number of moving pieces and some of the news on the commercial side, any change in your outlook between the subsegments between products and service for the full year here? Just to confirm on China, I think you talked about muted trends in China for the year, but just to be clear, you're not assuming any meaningful demand destruction tied to some of the tariff and trade war items out there. Thank you.
Robert Stefanovich (CFO)
Yeah, yeah, just to cover the last point first, China is not included or any change in China is not included in our guidance. That would be on top of that. If you look at the guidance and the overall services revenue growth and product revenue growth, it still is the same in terms of the guidance. We certainly see kind of an improved demand coming back on the product side, but still, from a guidance perspective, we'd say low to mid-single growth for the product side. On the services side, you can see strong growth in Q1, really on all aspects. Whether you look at overall revenue growth on services, the commercial revenue growth of 33%, and like Mark mentioned, the biostorage bioservices growth of 22%.
Jerrell Shelton (CEO)
Even if you look at commercial revenue, if you look at a trailing 12-month basis, it's about 26% year-over-year growth. We certainly expect commercial revenue to grow significantly and expect 2025 to be a record revenue for the support of our commercial clients.
Robert Stefanovich (CFO)
Great. Appreciate all the color. Thank you.
Operator (participant)
Thank you. The next question comes from Paul Knight with KeyBanc. Please go ahead.
Anna Snopkowski (Equity Research Analyst)
Hi, this is Anna on for Paul Knight. Thanks for taking my question. I have just one, but maybe touching on the recent news with DHL. I was wondering if you could make any initial comments on the impact of this partnership and if you've seen any benefit of being carrier-agnostic, maybe in terms of customer conversations or if this just increases your ability to meet the incoming pipeline of larger cell and gene therapies. Thanks.
Jerrell Shelton (CEO)
Yeah, the strategic relationship with DHL is an incredibly strong relationship for us. It will help increase our competitiveness in Asia-Pacific and EMEA. We will continue with our CRYOPDP as a partner and as a part of DHL, and that will be CRYOPDP on steroids because it will have all of the backing and the resources of DHL at its command. We have all of the other resources available to us at DHL. This is a very strong relationship and will, over time, ramp up to be quite significant for us on a global basis.
Robert Stefanovich (CFO)
Maybe just from a financial perspective, if you look at the strategic relationship and transaction itself, it certainly, obviously, significantly fortifies and strengthens our balance sheet and financial position. If you look at kind of the margin metrics for us as a company going forward longer term, it is significantly also an improvement in margins for the continuing operations.
Anna Snopkowski (Equity Research Analyst)
Thank you. That's great.
Operator (participant)
Thank you. There are no further questions at this time. Let me turn the call over to the manager for closing remarks.
Jerrell Shelton (CEO)
Thank you. Thank you, everyone, for your questions and for our discussions. In closing, we reported solid first-quarter results led by our life sciences services business, which grew 17% year-over-year. This included strong increases in commercial cell and gene therapy revenue and biostorage bioservices revenue, which increased year-over-year 33% and 23%, respectively. At the same time, we continued to see further stabilization of order trends in our life sciences product segment. In line with our focus on growing our role in supporting regenerative medicine with temperature control supply chain solutions, we are excited about our strategic partnership with DHL. This collaboration will advance our strategy and further enable us as the regenerative medicine industry's essential supply chain company. In addition, it will strengthen our financial profile, as Robert just mentioned, while sharpening our focus on our core business. We want to thank you for joining us today.
We appreciate your continued support and interest in our company. We're looking forward to updating you on our progress when we report on our second-quarter financial results. A good evening to all.
Operator (participant)
Thank you. Ladies and gentlemen, this concludes today's conference call. Thank you for your participation. You may now disconnect.