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Craig Wheeler

Director at AMICUS THERAPEUTICSAMICUS THERAPEUTICS
Board

About Craig A. Wheeler

Independent director since June 2016; age 64. CEO of Headwaters Biotech Advisors LLC; former President & CEO of Momenta Pharmaceuticals (grew from startup to a $6.5B acquisition by J&J in 2020; E&Y Entrepreneur of the Year Regional Award 2011; Boston Globe “Globe 100” #1 company in 2012). Prior roles include President of Chiron Biopharmaceuticals (more than doubled division sales), senior member of BCG’s healthcare practice, and early career at Merck’s MSDRL. Education: B.S. and M.S. Chemical Engineering (Cornell), MBA (Wharton). Wheeler is independent under Nasdaq rules and serves as Chair of Amicus’s Science & Technology Committee and member of its Audit & Compliance Committee .

Past Roles

OrganizationRoleTenureCommittees/Impact
Momenta Pharmaceuticals (Nasdaq: MNTA)President & CEO~14 years; to 2020Grew company through launches → $6.5B sale to J&J; E&Y award (2011); Globe 100 #1 company (2012)
Chiron BiopharmaceuticalsPresident5 yearsRan fully integrated 2,500-person global pharma; more than doubled global sales
The Boston Consulting GroupSenior member, healthcare practicePrior to ChironCorporate/R&D strategy across pharma/biotech
Merck (MSDRL)Research unitEarly careerScientific foundation in drug development
Avanir PharmaceuticalsChairman of the BoardUntil 2015Oversaw transition to fully integrated CNS pharma; acquired by Otsuka for $3.5B

External Roles

OrganizationRoleTenure/StatusNotes
Apellis Pharmaceuticals, Inc. (Nasdaq: APLS)DirectorCurrentPublic company board; enhances biotech industry insight

No related-party transactions disclosed involving Wheeler; the only Item 404 transaction noted was BIO membership dues related to Mr. Crowley’s role at BIO .

Board Governance

  • Committee assignments: Chair, Science & Technology; Member, Audit & Compliance. Independent director; Director since 2016 .
  • Attendance: Board met 6 times and committees met 22 times in 2024; each director attended ≥75% with overall 98% attendance; all directors attended the 2024 Annual Meeting .
  • Committee activity: Audit & Compliance met 5 times (Chair: Sblendorio); Science & Technology met 6 times (Chair: Wheeler; members: Kelly, Wheeler, Roberts) .
Committee2024 MeetingsWheeler Role
Audit & Compliance5 Member
Science & Technology6 Chair
  • Independence: Board majority independent; Wheeler determined independent under Nasdaq rules .
  • Governance processes: Annual board and committee self-evaluation administered by third party plus structured interviews; robust ERM oversight across committees .

Fixed Compensation (Director)

MetricFY 2024
Fees Earned or Paid in Cash ($)$77,165
Cash Fee Policy ComponentFY 2024 Rate
Board member annual retainer$50,000
Chairman of the Board$75,000 (from Mar 4, 2024)
Lead Independent Director$30,000
Audit & Compliance Committee Chair (incl. membership)$30,000
Compensation Committee Chair (incl. membership)$20,000
Nominating & Governance Committee Chair (incl. membership)$12,500
Science & Technology Committee Chair (incl. membership)$16,000
Audit & Compliance Committee member$10,000 (pre-Jun 1, 2024); $12,000 (effective Jun 1, 2024)
Compensation Committee member$10,000
Nominating or Science & Technology Committee member$7,500

Wheeler’s reported cash total of $77,165 reflects pro-ration across assignments and mid-year fee changes .

Performance Compensation (Director Equity)

ComponentFY 2024 ValueTerms
Stock Awards (RSUs) ($)$121,667 Annual grant vests at next Annual Meeting; grant date at Annual Meeting; RSUs comprise 1/3 of annual equity; newly appointed director RSUs vest 25% yearly over 4 years
Option Awards ($)$243,333 Options comprise 2/3 of annual equity; exercise price = 100% FMV at grant; 10-year term; annual grant vests at next Annual Meeting; initial director options vest 25% at year 1 then monthly over years 2–4
Total Annual Director Equity Grant ($)$365,000
Program change (YoY)Increased from $325,000 (2023) to $365,000 (2024)

Additional plan safeguards:

  • No option/SAR repricing without stockholder approval .
  • Dividends/dividend equivalents subject to same vesting as underlying awards; none payable on options/SARs .
  • Annual non-employee director compensation cap under 2025 Plan: $750,000 (from 2026; $1,000,000 in first year), excluding chair/lead independent fees and certain extraordinary circumstances .

Other Directorships & Interlocks

CompanyRoleCommittee Roles (if disclosed)Potential Interlocks/Conflicts
Apellis Pharmaceuticals (APLS)DirectorNot disclosedNone disclosed by Amicus; no related-party transactions reported involving Wheeler
Avanir Pharmaceuticals (prior)Chairman of the BoardNot disclosedAcquired by Otsuka in 2015; historical role

Expertise & Qualifications

  • Deep pharmaceutical leadership across R&D, manufacturing, clinical/regulatory strategy, and commercialization; aligns with Science & Technology Committee chair responsibilities .
  • Strategic acumen from BCG; technical foundation from Merck MSDRL; advanced engineering and business training (Cornell; Wharton) .

Equity Ownership

Ownership MetricValue
Shares Beneficially Owned311,887
Ownership % of Outstanding<1% (307,923,069 shares outstanding basis)
Options Outstanding (Aggregate)247,670
Options – Vested / Unvested205,203 / 42,467
Director Stock Ownership Guideline3× annual retainer; 5-year window to attain; compliance monitored; directors “met or are on track”
Hedging/PledgingProhibited for directors; no short sales; no margin/pledge activity permitted

Governance Assessment

  • Strengths: Independent status; chairs S&T with relevant domain expertise; Audit membership supports risk and compliance oversight; strong attendance (board/committee aggregate 98%) and engagement; anti-hedging/pledging policy; stock ownership guidelines with monitored compliance .
  • Alignment: Director pay tilted toward equity (2/3 options, 1/3 RSUs) with annual vest; ownership guidelines and prohibition on hedging/pledging enhance alignment; options feature full FMV strike and 10-year term .
  • Pay structure changes: Annual director equity grant increased to $365,000 in 2024 (from $325,000), consistent with market review; oversight guardrails include a formal director compensation cap in the 2025 Plan starting FY2026 .
  • Related-party/conflicts: No Wheeler-specific related-party transactions disclosed; only BIO dues tied to Mr. Crowley noted for 2024 .
  • Shareholder sentiment: Recent say-on-pay approval ~97% (advisory) suggests broad support for compensation governance, though focused on NEOs; still relevant for overall pay philosophy .

RED FLAGS to monitor

  • Pay inflation risk: Upward adjustment of director equity grant (2024) warrants continued benchmarking against peers and alignment with workload/meeting cadence .
  • Multi-board service: External public board at Apellis increases time commitments; no conflict disclosed, but monitor for any business overlaps or transactions that could trigger related-party review .