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Harold E. Brakewood

Chief Business Officer at Immuneering
Executive

About Harold E. Brakewood

Harold E. “E.B.” Brakewood, age 60, is Chief Business Officer at Immuneering, serving in this role since March 2023. He previously led an oncology/COVID-19/new product planning business unit at Regeneron (2015–2021) and held a series of senior commercial roles at Merck (1989–1992; 1994–2015). He holds an A.B. from Bowdoin College, an M.A. in physics from Dartmouth, and an M.B.A. from Harvard Business School . Executive-level TSR/revenue/EBITDA performance metrics are not disclosed in IMRX proxy materials; 2023 cash bonus decisions cited program progress (IMM-1-104 Phase 1/2a), an IND filing (IMM-6-415), and successful financing, indicating incentives tied to clinical and capital-raising milestones .

Past Roles

OrganizationRoleYearsStrategic Impact
Immuneering CorporationChief Business Officer2023–PresentExecutive officer overseeing business functions; joined March 2023
Regeneron PharmaceuticalsVice President; head of business unit (oncology, COVID-19, new product planning)2015–2021Led multi-therapy business unit spanning oncology and COVID-19 as well as new product planning
Merck & Co., Inc.Commercial roles (strategic planning, BD, brand management, oncology venture)1989–1992; 1994–2015Progressive commercial leadership including strategic planning/business development and oncology venture formation

External Roles

No external public-company directorships or committee roles are disclosed for Brakewood in IMRX proxy materials .

Fixed Compensation

YearBase Salary Rate ($)Actual Salary Paid ($)Target Bonus %Actual Bonus Paid ($)All Other Compensation ($)Total ($)
2023425,000 326,923 40% 142,940 13,137 1,474,023
2024442,000 (effective Jan 1, 2024) 40% (no change disclosed)

Notes:

  • 2024 actual compensation for Brakewood is not itemized in the 2024/2025 Summary Compensation Tables (not a named executive officer for 2024); base rate increases are disclosed in his employment agreement .

Performance Compensation

Annual Cash Bonus (2023)

MetricWeightingTargetActualPayout ($)Vesting
Company performance objectives: progress of IMM-1-104 Phase 1/2a, IND filing for IMM-6-415, completion of $30M follow-on equity offeringNot disclosed Not disclosed Approved above target based on 2023 performance 142,940 Cash (n/a)

Equity Incentives (Stock Options)

Grant DateTypeSharesStrike Price ($)Grant-Date Fair Value ($)Vesting ScheduleExpiration
Mar 2023Nonqualified Stock Options165,000 9.71 991,023 (2023 option awards reported) 25% on first anniversary of 1/23/2023, then equal monthly over next 3 years (time-based) 3/31/2033
May 21, 2024 (repricing)Repriced Eligible Options3.01 (effective) with reversion to original strike if exercised before 6/30/2025, absent CoC or qualifying termination Existing vesting terms unchanged; retention period through 6/30/2025 applies to exercise pricing Existing expirations unchanged

Notes:

  • Option repricing explicitly included current employees “including E.B. Brakewood,” setting repriced strike at $3.01 with a retention-period reversion clause through 6/30/2025 (exceptions: change of control or termination by company without cause/death/disability) .

Equity Ownership & Alignment

ItemDetail
Total beneficial ownership65,202 shares; less than 1% of Class A common stock outstanding as of April 18, 2024
Options (12/31/2023)0 exercisable; 165,000 unexercisable; strike $9.71; expiration 3/31/2033
Shares pledged as collateralNot disclosed (no pledging noted)
Stock ownership guidelinesCompany has no formal executive equity ownership guidelines
Compliance statusNot applicable (no guidelines)

Employment Terms

TermDetail
Employment agreementIndefinite term; effective March 24, 2023; role: Chief Business Officer
Base salary & target bonusInitial base $425,000; increased to $442,000 effective Jan 1, 2024; target annual bonus 40% of base
Equity grantOption to purchase 165,000 shares under 2021 Plan (granted Mar 2023)
Severance (termination without cause or resignation for good reason)12 months base salary; unpaid prior-year bonus; direct payment/reimbursement of COBRA premiums (employee-rate offset) for up to 12 months (subject to release and covenants)
Change of Control (double-trigger within 12 months)In lieu of above: 12 months base salary; unpaid prior-year bonus; 1.0x target annual bonus; COBRA premiums up to 12 months; full acceleration of all time-based equity awards (subject to release and covenants)
Restrictive covenantsNon-compete and non-solicit during employment and for one year post-termination; confidentiality continuing
Clawback policyCompany adopted Nasdaq Rule 10D-1-compliant clawback policy in 2023 for recovery of erroneously received incentive compensation (3-year look-back upon restatement)
Tax gross-upsNone disclosed

Investment Implications

  • Pay-for-performance drivers: Bonus outcomes tied to clinical execution and financing milestones (IMM-1-104 Phase progression, IMM-6-415 IND, capital raise); this aligns cash incentives with pivotal program advancement and funding access . Equity is primarily options with time-based vesting, creating leverage to share price but without explicit performance vesting .
  • Retention and selling pressure: May 2024 option repricing to $3.01 with a retention-period reversion until 6/30/2025 lowers near-term exercise economics unless a change-of-control or qualifying termination occurs, thereby strengthening retention but potentially deferring insider exercises through the retention horizon .
  • Alignment risk: Beneficial ownership is modest (<1%), and the company has no executive equity ownership guidelines—together signaling limited “skin in the game” versus peers with formal ownership policies .
  • Change-of-control economics: Double-trigger structure with 12 months salary + 1x target bonus and time-based equity acceleration is moderate and shareholder-standard, reducing windfall risk while ensuring continuity incentives in strategic scenarios .
  • Governance signals: Adoption of a 10D-1 clawback policy is positive; however, option repricing for underwater grants is a compensation red flag at some investors—here designed to avoid incremental dilution/cash comp and bolster retention across employees (Brakewood included) .