Earnings summaries and quarterly performance for Immuneering.
Executive leadership at Immuneering.
Benjamin J. Zeskind
President and Chief Executive Officer
Brett Hall
Chief Scientific Officer
Harold E. Brakewood
Chief Business Officer
Igor Matushansky
Chief Medical Officer
Leah R. Neufeld
Chief People Officer
Mallory Morales
Chief Accounting Officer and Treasurer
Michael D. Bookman
Chief Legal Officer and Secretary
Board of directors at Immuneering.
Research analysts who have asked questions during Immuneering earnings calls.
Jeff Hung
Morgan Stanley
1 question for IMRX
Mark Breidenbach
Oppenheimer & Co. Inc.
1 question for IMRX
Michael Schmidt
Guggenheim Securities
1 question for IMRX
Michael Yee
Jefferies
1 question for IMRX
Swapnil Malekar
Piper Sandler
1 question for IMRX
Yaron Werber
TD Cowen
1 question for IMRX
Recent press releases and 8-K filings for IMRX.
- Immuneering announced 12-month overall survival of 64% for atebumetanib plus chemotherapy in first-line pancreatic cancer patients, significantly higher than the historical benchmark of approximately 35% for standard of care.
- The median overall survival for atebumetanib has not yet been reached at a median follow-up of 13.4 months, compared to approximately 8.5 months for standard of care, and the drug demonstrated a favorable safety and tolerability profile with dramatic improvements in quality of life.
- The company plans to initiate its pivotal Phase 3 clinical trial (MapKeeper 301) for atebumetanib in first-line pancreatic cancer patients in mid-2026, with top-line results anticipated in mid-2028.
- Immuneering maintains a strong financial position with a cash runway extending into 2029, which is expected to fund the company through the pivotal data readout and the initiation of additional trials.
- Immuneering Corporation announced on January 7, 2026, positive 12-month overall survival (OS) data from its phase 2A trial of atebumetanib in first-line pancreatic cancer patients.
- The trial demonstrated a 64% OS rate at 12 months, nearly double the approximately 35% historical benchmark for standard of care, with median OS not yet reached.
- The company plans to initiate a pivotal phase 3 clinical trial (MapKeeper 301) for atebumetanib in first-line pancreatic cancer, with dosing expected to begin in mid-2026 and top-line results anticipated in mid-2028.
- Immuneering maintains a strong financial foundation with a cash runway extending into 2029, supporting key development milestones including the phase 3 data readout.
- An update on overall survival from an expanded cohort of over 50 patients is expected in the first half of 2026, with current trends showing consistency with the initial 34 patients.
- Immuneering (IMRX) announced positive 12-month overall survival (OS) data from its ongoing Phase 2A trial of atebumetanib in first-line pancreatic cancer patients, achieving 64% OS compared to a historical benchmark of approximately 35% for standard of care.
- The median overall survival for atebumetanib in the study has not yet been reached, with a median follow-up time of 13.4 months.
- The trial also demonstrated significant improvements in secondary endpoints, including a median progression-free survival of 8.5 months (compared to 5.5 months for standard of care) and an overall response rate of 39% (compared to 23%).
- Immuneering plans to initiate a pivotal Phase 3 clinical trial (MapKeeper 301) for atebumetanib in first-line pancreatic cancer, with dosing expected to begin in mid-2026 and top-line results anticipated in mid-2028.
- The company reported a strong financial foundation with a cash runway into 2029, which is expected to fund through the pivotal data readout and initiation of additional trials.
- Immuneering Corporation announced updated interim data from its Phase 2a clinical trial for atebimetinib in first-line pancreatic cancer patients, showing 64% overall survival (OS) at 12 months compared to 35% for standard of care, as of a December 15, 2025 cutoff date.
- The trial reported a median progression-free survival (PFS) of 8.5 months, and the median OS had not yet been reached for the initial intent-to-treat population of 34 patients.
- Atebimetinib in combination with mGnP continued to be generally well tolerated, with Grade ≥ 3 treatment-emergent adverse events (TEAEs) observed in 10% or greater of patients consisting of Anemia (18%) and Neutropenia (18%), and no Grade 5 TEAEs or new safety signals identified.
- The company anticipates dosing the first patient in a pivotal Phase 3 clinical trial of atebimetinib in first-line pancreatic cancer in mid-2026, and announcing further updated survival data in the first half of 2026.
- Immuneering Corporation (IMRX) will host a conference call and webcast on January 7, 2026, at 4:00 p.m. ET to provide a clinical update.
- The update will include 12-month overall survival (OS) data from its Phase 2a clinical trial of atebimetinib + modified Gemcitabine / nab-paclitaxel (mGnP) in first-line pancreatic cancer patients.
- The company expects to begin dosing a Phase 3 trial for atebimetinib in first-line pancreatic cancer in mid-2026.
- Immuneering Corporation reported an 86% overall survival at 9 months in first-line pancreatic cancer patients treated with atebimetinib in combination with modified gemcitabine/nab-paclitaxel (mGnP).
- The company raised $225 million in cumulative financing, including a $25 million private placement with Sanofi.
- Immuneering's cash position of $227.6 million as of September 30, 2025, extends its financial runway into 2029, covering the topline readout of its planned Phase 3 trial.
- The company expects to report updated survival data from its atebimetinib + mGnP study in the first half of 2026 and plans to dose the first patient in its pivotal Phase 3 trial by mid-2026.
- Immuneering reported extraordinary overall survival data and favorable tolerability from its Phase 2A study of Etabimetinib in first-line pancreatic cancer patients, showing 94% overall survival at six months and 86% at nine months as of August 26, 2025.
- These results represent a significant improvement over the standard of care, with a 27-point separation in overall survival at six months and a 39-point separation at nine months compared to typical expectations for gemcitabine-nab-paclitaxel.
- The company plans to initiate a global randomized Phase 3 study for Etabimetinib in first-line pancreatic cancer, with the first patient expected to be dosed in mid-2026.
- Recent financing and strategic investment have provided Immuneering with a financial runway into 2029.
- Immuneering announced extraordinary overall survival data and favorable tolerability from its ongoing Phase 2A study of Etabimetinib plus modified gemcitabine/nab-paclitaxel in first-line pancreatic cancer patients.
- As of August 26, 2025, the study demonstrated 94% overall survival at six months and 86% overall survival at nine months, showing a significant separation from the standard of care.
- A Phase 3 study for Etabimetinib in first-line pancreatic cancer is projected to begin dosing patients in mid-2026, with overall survival as the primary endpoint.
- The company's recent financing and strategic investment provides a financial runway into 2029.
- Immuneering significantly strengthened its balance sheet, reporting $227.6 million in cash and cash equivalents as of September 30, 2025, extending its cash runway into 2029. This was supported by $225 million in cumulative financing, including a $25 million strategic investment from Sanofi.
- The company presented two remarkable case studies from its Phase 2A trial of Tevid MetNib in combination with FOLFIRINOX for first-line pancreatic cancer, demonstrating significant tumor reduction, including an unconfirmed complete response and a patient becoming eligible for curative surgery.
- Immuneering plans to report updated survival data in the first half of 2026 for Tevid MetNib in combination with gemcitabine nab-paclitaxel, building on the 86% overall survival at nine months reported in September for 34 first-line pancreatic cancer patients.
- The first patient in the pivotal Phase 3 trial of Tevid MetNib in combination with modified gemcitabine nab-paclitaxel in first-line pancreatic cancer is expected to be dosed in mid-2026, pending regulatory feedback. Additionally, the company announced plans to dose the first patient in a trial of Tevid MetNib with Regeneron's Libtayo in advanced lung cancer in the second half of 2026.
- Immuneering Corporation reported extraordinary 86% overall survival at 9 months in first-line pancreatic cancer patients treated with atebimetinib + mGnP in its Phase 2a trial.
- The company raised $225 million in financing, including a $25 million private placement with Sanofi, which has extended its cash runway into 2029.
- Immuneering was granted a U.S. composition of matter patent for atebimetinib, expected to provide exclusivity into 2042.
- For the third quarter ended September 30, 2025, Immuneering reported a net loss of $15.0 million, or $0.38 per share, and held $227.6 million in cash and cash equivalents.
Quarterly earnings call transcripts for Immuneering.
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