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Hervé Hoppenot

Hervé Hoppenot

Chief Executive Officer at INCYTEINCYTE
CEO
Executive
Board

About Hervé Hoppenot

Hervé Hoppenot is Chair of the Board and President & CEO of Incyte, age 65, serving as director since 2014 and appointed Chair in May 2015; he previously led Novartis Oncology and held senior commercial roles at Novartis and Aventis/RPR . Incyte’s executive pay emphasizes performance: CEO equity awards are 60% performance shares tied to relative TSR, 20% stock options, 20% RSUs, with clawbacks and strict anti-hedging/pledging policies; most important performance measures include total product revenues, pipeline progression, and TSR .

Past Roles

OrganizationRoleYearsStrategic Impact
Novartis Pharmaceuticals (Novartis Oncology)President2010–2014Led global oncology business; commercial leadership and strategy
Novartis PharmaceuticalsEVP, Chief Commercial Officer (Oncology); Head of Global Product Strategy & Scientific Development2006–2010Drove global product strategy and commercialization
Novartis Pharmaceuticals (Oncology)SVP, Head of Global Marketing2003–2006Led global oncology marketing
Aventis Pharmaceuticals (formerly Rhône-Poulenc)VP Oncology US2000–2003Ran US oncology operations
Rhone-Poulenc Rorer PharmaceuticalsVP US Oncology Operations1998–2000Managed US oncology business

External Roles

OrganizationRoleYearsStrategic Impact
Other Outside Public BoardsNoneNo outside public board service disclosed

Fixed Compensation

Metric202220232024
Base Salary ($)1,227,151 1,291,929 1,344,707
Non-Equity Incentive (Annual Cash Bonus) ($)1,602,926 1,554,703 2,202,829
All Other Compensation ($)56,142 53,187 53,298
Total Compensation ($)16,669,368 16,659,526 17,459,546
2025 Base Salary SettingValue
2024 Base Salary ($)1,348,533
2025 Increase (%)3.5%
2025 Base Salary ($)1,395,731
2024 All Other Compensation DetailAmount ($)
Life Insurance Premiums7,524
Financial Planning Services (incl. tax gross-up $8,061)23,061
Statutory Fee (Director of EU Subsidiary)4,400
401(k) Matching Contributions18,313

Performance Compensation

Annual Incentive Plan (2024)

MetricThreshold ($)Target ($)Maximum ($)Actual Payout ($)Notes
Annual Cash Incentive1,112,540 1,483,386 2,818,434 2,202,829 Plan varies with performance; most important measures include total product revenues, pipeline, TSR

2024 Equity Grants (Design and Awards)

InstrumentGrant DateQuantity / TargetsExercise/Base Price ($)Grant Date Fair Value ($)Vesting / Performance
Stock Options01/18/202497,566 (footnote (5)) 61.18 1,996,144 Options vest per schedules described; typical 7–10 year terms and multi-year vesting
Stock Options07/15/202461,189 (footnote (6)) 64.25 1,319,079 Options vest per schedules described
Performance Shares (Relative TSR)07/15/2024Threshold 61,538; Target 123,076; Max 246,152 7,907,633 3-year cliff vest; multiplier 50%–200% based on discrete percentile rank; threshold at 25th percentile; target at 50th; 90th percentile max; cap at 100% if absolute TSR negative
RSUs07/15/202441,025 (footnote (4)) 2,635,856 Vests per RSU schedule; generally equal installments over 4 years
2024 CEO Equity MixWeighting
Performance Shares60% of equity grant value
Stock Options20% of equity grant value
RSUs20% of equity grant value

Earned Performance Shares (Prior Cycles and Vesting)

Award CohortEarned (%)Vesting Date
Performance shares granted July 2022 (US executives)110.7% Third anniversary of Jul 2, 2022 grant (Jul 2, 2025), subject to continued service
Performance shares granted Dec 2022 (Opzelura goals)123.0% Nov 30, 2025, subject to continued service

PSU Design (Relative TSR)

MetricWeightingThresholdTargetMaximumSpecial Cap
Relative TSR vs fixed NBI-based peer group100% of PSUs for 2024–2025 25th percentile (50% multiplier) 50th percentile (100% multiplier) 90th percentile (200% multiplier) If absolute TSR is negative, cap at 100% even if >50th percentile

Equity Ownership & Alignment

ItemDetail
Beneficial Ownership (Apr 15, 2025)1,662,988 shares; less than 1% of outstanding
2024 Stock Vested101,591 shares; value realized $6,052,364; 46,684 shares withheld for taxes
2024 Option ExercisesNone
CEO Ownership Guideline6x annual base salary; CEO has met requirement
Hedging/PledgingProhibited by insider trading policy (no short-term trading, margin, short sales, options, pledging, hedging/monetization)

Employment Terms

ProvisionKey Terms
Initial RSU make-whole grant400,000 RSUs in Jan 2014; vesting one-sixth annually 2014–2019
Life & Disability Insurance (legacy)Company paid premiums for six years starting 2014 for $15 million benefit; tax gross-ups removed in Apr 2015; premiums stopped in 2019 at CEO’s suggestion
Post-Retirement VestingFor awards granted after Jul 15, 2019 and before Dec 31, 2024, continued vesting after retirement (post-Dec 31, 2024) subject to covenant compliance; options exercisable for remainder of term
CovenantsNon-solicitation/non-hiring and non-disparagement for 2 years post-termination; breach triggers forfeiture of unvested equity and recovery of gains in prior 24 months
Termination without cause or for good reason (not in CoC)Cash severance equal to 1.5x annual base salary plus greater of target or prior-year actual bonus; pro-rata current-year bonus; equity: options/RSUs vest as if employed 18 more months; options exercisable 180 days; COBRA premiums up to 12 months; outplacement up to 12 months; other accrued amounts
CoC termination without cause or for good reason (double trigger)Cash severance equal to 3x current annual base salary plus greater of target or prior-year actual bonus; full vesting of unvested RSUs and options; performance shares vest at target and settle; options exercisable 12 months; benefits continued up to 36 months; outplacement up to 12 months; other accrued amounts
Termination without good reason during CoC periodPro-rata target bonus; salary/deferrals/vacation through termination
Potential Payments upon CoC Termination (as of Dec 31, 2024)Cash $10,136,041; Medical/Insurance $76,448; Equity acceleration $29,720,081; Other $623,127; Total $40,555,697

Board Governance

  • Board Service: Director since 2014; Chair since May 2015; no committee memberships; not independent as CEO .
  • Dual-role implications: Board combines Chair/CEO with robust Lead Independent Director (Julian C. Baker) representing Baker Funds (~16% ownership) to mitigate independence concerns; duties include agenda, information approval, liaison, and presiding over executive sessions .
  • Majority voting policy and independence focus disclosed; Board maintains annual review of leadership structure .

Compensation Committee Analysis

  • Committee composition: all independent directors; uses independent consultant Compensia; conducts peer benchmarking; annual say-on-pay .
  • Equity mix remains performance-heavy; CEO 2024 grant date target value $12.4M; planned 2025 target $14.0M; PSUs cliff vest over three years; stock options 10-year life and multi-year vest align with long development cycles; double-trigger CoC equity vesting .

Risk Indicators & Red Flags

  • Anti-hedging/pledging; no option repricing; no excise tax gross-ups for golden parachutes; robust clawback policy compliant with SEC/Nasdaq plus legacy restatement clawback .
  • Perquisite tax gross-ups appear for certain benefits (e.g., financial planning services), albeit small in magnitude .
  • Large potential CoC payout and full acceleration of equity could create event-driven selling pressure if a transaction occurs .

Equity Ownership & Beneficial Owners (Context)

HolderShares% of Outstanding
Baker Bros. Advisors LP & affiliates30,866,714 15.9%
Julian C. Baker31,224,792 (overlapping structure) 16.1%
Vanguard22,519,381 11.6%

Investment Implications

  • Retention risk appears low given post-retirement vesting protections on grants through 2024, strong equity ownership compliance, and long equity vesting tails; covenants and clawbacks add retention leverage .
  • Near-term vesting events (Jul 2, 2025 and Nov 30, 2025) for previously earned performance shares are potential supply catalysts from tax withholding or 10b5-1 plan sales; monitoring Form 4s and preset plans is warranted .
  • Pay-for-performance alignment is solid: majority at-risk equity, relative TSR-only PSUs for 2024–2025 with appropriate caps; annual incentive targets/payouts indicate above-target operating execution in 2024, supporting confidence in pipeline/commercial priorities .
  • Governance: CEO/Chair dual role is mitigated by an empowered Lead Independent Director representing a 16% shareholder, reducing independence concerns; however, event-driven CoC economics (~$40.6M total potential) and full equity acceleration merit attention in deal scenarios .