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Athena Countouriotis

Director at IOVANCE BIOTHERAPEUTICSIOVANCE BIOTHERAPEUTICS
Board

About Athena Countouriotis

Athena Countouriotis, M.D., age 53, has served as an independent director of Iovance since 2019. She is co‑founder and Chief Executive Officer of Avenzo Therapeutics (private), and previously was President & CEO of Turning Point Therapeutics until its acquisition by Bristol‑Myers Squibb in August 2022. She holds an undergraduate degree from UCLA, an M.D. from Tufts University School of Medicine, and completed pediatric hematology‑oncology training at UCLA and Fred Hutchinson; earlier roles include drug development leadership at Pfizer and Bristol‑Myers Squibb for Sutent, Mylotarg, Bosulif, and Sprycel. The Board discloses that six of seven directors are independent, with only the interim CEO non‑independent, which includes Dr. Countouriotis .

Past Roles

OrganizationRoleTenureCommittees/Impact
Turning Point TherapeuticsPresident & CEO; Director2018–Aug 2022Led growth to acquisition by Bristol‑Myers Squibb
Adverum BiotechnologiesChief Medical OfficerNot disclosedCMO experience cited
Halozyme TherapeuticsChief Medical OfficerNot disclosedCMO experience cited
Ambit BiosciencesChief Medical OfficerNot disclosedCMO experience cited
PfizerProduct development leader (Sutent, Mylotarg, Bosulif)Not disclosedLed development of multiple oncology products
Bristol‑Myers SquibbProduct development leader (Sprycel)Not disclosedLed development of oncology product

External Roles

OrganizationRoleTenureCommittees/Impact
BioMarin PharmaceuticalDirectorCurrentBoard service; committees not disclosed
Passage BioDirectorCurrentBoard service; committees not disclosed
Capstan Therapeutics (private)DirectorCurrentBoard service
Leal Therapeutics (private)DirectorCurrentBoard service
Recludix Therapeutics (private)DirectorCurrentBoard service
Avenzo Therapeutics (private)Co‑founder & CEOCurrentOperating leader

Board Governance

  • Committee assignments: Compensation Committee member; Nominating & Corporate Governance Committee member. Not a committee chair. Audit Committee members are Maynard (Chair), Weiser, Yarno .
  • Attendance and engagement: The Board held six meetings in FY2024; executive sessions were held for each regular Board and standing committee meeting. Dr. Countouriotis attended all committee meetings but missed one or more Board meetings; “other than Dr. Countouriotis, no director attended fewer than 75%” of aggregate Board and committee meetings, indicating she fell below the 75% threshold in aggregate attendance. Audit Committee held 4 meetings; Compensation Committee 2; Nominating & Corporate Governance Committee 1, with additional actions by written consent .
  • Independence: The Board determined six of seven current directors are independent under Nasdaq and SEC rules; only the interim CEO is not independent .

Fixed Compensation

ComponentAmount ($)Notes
Board annual cash retainer$50,000Payable quarterly, in arrears
Committee membership fee (per committee)$7,500Compensation and Nominating committees (member)
Committee chair fees (if applicable)$15,000Not applicable to Dr. Countouriotis
Chairman extra retainer (if applicable)$25,000Not applicable
Actual cash received (2024)$65,000Reflects board retainer + two committee memberships

Policy context:

  • Non‑employee director cash retainers and annual equity do not exceed the 75th percentile of peer group comparator data; peer group assessed annually by the Compensation Committee with an independent consultant .
  • No more than 60% of a director’s annual and initial equity award value may be granted as stock options; in 2024, 100% of director equity was DRSUs .

Performance Compensation

Award TypeGrant DetailVesting / Deferral2024 Grant Date Fair Value ($)Notes
Annual DRSU grant (policy)Target $425,000Vests on earlier of 1 year from grant or day prior to next annual meeting; share delivery automatically deferred until 90 days after director ceases service (except change‑in‑control/other events) Not individually disclosed2024 equity delivered entirely in DRSUs per policy
Special DRSU (BLA approval recognition)50,000 DRSUs to Dr. CountouriotisPer 2018 Plan and director policy, special awards for extraordinary achievement do not count toward annual award limits Included in total belowAward recognizes time commitment and value creation from FDA approval of Amtagvi (lifileucel)
Total DRSU awards (2024)Aggregate DRSUs valued per ASC 718See features above; standard DRSUs + special award$1,264,492Company methodology per 10‑K Notes 2 and 10

Performance metrics tied to director compensation: None disclosed; director equity comprises time‑based DRSUs with automatic deferral; no TSR/financial metric linkage for directors .

Other Directorships & Interlocks

CompanyRelationship to IovanceInterlock/Conflict Notes
BioMarin PharmaceuticalUnrelated public biotechNo Iovance related‑party transactions disclosed in 2024
Passage BioUnrelated public biotechNo Iovance related‑party transactions disclosed in 2024
Private boards (Capstan, Leal, Recludix)Unrelated private biotechNo Iovance related‑party transactions disclosed in 2024

Policies: Audit Committee reviews and approves any related‑person transactions; none >$120,000 in 2024 involving directors, NEOs, 5% holders or immediate family were reported .

Expertise & Qualifications

  • Oncology physician with executive leadership across multiple public biotechs (CMO roles) and CEO experience at Turning Point Therapeutics; extensive oncology drug development pedigree at Pfizer and Bristol‑Myers Squibb (Sutent, Mylotarg, Bosulif, Sprycel) .
  • Current operating CEO (Avenzo Therapeutics) and public company board experience (BioMarin, Passage Bio), supporting scientific and clinical oversight on Iovance’s Compensation and Nominating & Governance committees .

Equity Ownership

Ownership ItemAmountNotes
Beneficial ownership (common stock)105,000 sharesLess than 1% of class as of Record Date; ownership computed per SEC rules including exercisable/convertible within 60 days
DRSUs outstanding (aggregate)202,462 unitsAs of Dec 31, 2024; share delivery deferred per policy
Hedging/derivativesProhibitedNo short‑selling, puts/calls, or hedging allowed for directors per Insider Trading Policy
Pledging/marginProhibitedNo holding in margin accounts or pledging as loan collateral

Compliance with director stock ownership guidelines: Not disclosed; Iovance uses deferred RSUs and automatic deferral post‑service to promote long‑term alignment .

Governance Assessment

  • Strengths:

    • Independent director with deep oncology and drug development credentials; service on Compensation and Nominating & Governance committees aligns with expertise .
    • Robust governance policies: majority‑independent board, annual elections by majority vote, non‑executive chair, regular executive sessions; hedging/pledging prohibited; independent compensation consultant policy .
    • No related‑party transactions reported for 2024 involving directors or 5% holders, reducing conflict‑of‑interest risk .
    • Compensation Committee Interlocks: none disclosed for 2024 (positive) .
  • Concerns and signals:

    • RED FLAG: Attendance. Disclosure indicates Dr. Countouriotis attended all committee meetings but missed one or more Board meetings, and “other than Dr. Countouriotis, no director attended fewer than 75%” of aggregate Board and committee meetings, implying her aggregate attendance fell below the 75% threshold in FY2024 .
    • Time commitments. Concurrent CEO role at Avenzo and multiple external directorships may pose capacity constraints; although the proxy states she can devote necessary time, the attendance shortfall is a negative signal for board effectiveness .
    • Compensation optics. 2024 director equity value materially above standard annual policy ($425,000) due to special DRSUs recognizing FDA approval. While permitted and tied to an extraordinary achievement, investors may scrutinize the scale and precedent of such awards to directors .
  • Alignment:

    • Deferred RSUs structure and insider trading restrictions support long‑term alignment; no pledging allowed, and share delivery delayed until 90 days post‑service .
  • Shareholder sentiment:

    • Annual say‑on‑pay votes have been approved since 2017 (executive pay), suggesting general support for compensation programs; not specific to director pay but relevant to overall governance climate .