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Daniel Kirby

Chief Commercial Officer at IOVANCE BIOTHERAPEUTICSIOVANCE BIOTHERAPEUTICS
Executive

About Daniel Kirby

Daniel Kirby is Chief Commercial Officer at Iovance Biotherapeutics, appointed effective February 10, 2025; he is 53 years old and brings deep commercial expertise in cell therapy across launch readiness, market access, and reimbursement . His background includes CCO roles at Orca Bio and Omeros (2018–2020), and senior commercial leadership for CAR‑T at Celgene/Juno, plus marketing leadership at Medivation and a 14‑year tenure in commercial roles at Amgen . Iovance’s executive pay framework emphasizes pay‑for‑performance aligned to commercial, clinical, regulatory and operational goals rather than specific financial measures; Kirby’s compensation will be evaluated within this structure .

Past Roles

OrganizationRoleYearsStrategic Impact
Orca BioChief Commercial OfficerNot disclosedLed global commercial strategy and operations for an emerging cell therapy platform .
Omeros CorporationChief Commercial Officer2018–2020Oversaw U.S./EU launch readiness for narsoplimab and all commercial activities for Omidria .
Celgene (now Bristol‑Myers Squibb)VP & Head of US Cell & GeneNot disclosedLed market access, reimbursement, and marketing for CAR‑T products .
Juno TherapeuticsVP of Marketing & Market AccessNot disclosedJoined Celgene following Juno acquisition; led marketing/access for cell therapy .
Medivation (now Pfizer)Head of MarketingNot disclosedMarketing leadership for oncology portfolio .
AmgenVarious commercial roles14 yearsProgressive commercial leadership across therapeutic franchises .

External Roles

None disclosed in company filings for Kirby (no public company directorships or committee roles identified) .

Fixed Compensation

  • Base salary, target bonus %, and actual bonus paid for Kirby have not been disclosed; the 2025 proxy’s NEO disclosures cover 2024 executives and do not include Kirby (joined in 2025) .

Performance Compensation

Incentive TypeShares/UnitsGrant DateStrike/Grant PriceVesting SchedulePerformance Metrics
Inducement stock optionsNot disclosed (part of aggregate 305,000)Feb 10, 2025Exercise price = closing price on grant dateOne‑third vests on first anniversary of employee start date; remaining vests in eight quarterly installments over next two years, subject to continued employmentNot performance‑based for options .
Inducement RSUsNot disclosed (part of aggregate 305,000)Feb 10, 2025N/A (RSUs)One‑third vests on first anniversary of employee start date; remaining vests in eight quarterly installments over next two years, subject to continued employmentCertain RSUs may vest upon achievement of performance milestones tied to specified financial results (details not disclosed) .
Aggregate inducement awards (options + RSUs)Up to 305,000 sharesFeb 10, 2025See aboveSee aboveSee above .

Additional context:

  • Inducement awards granted under the Amended & Restated 2021 Inducement Plan pursuant to Nasdaq Listing Rule 5635(c)(4) for new hires .
  • Iovance’s annual incentives generally tie to commercial, regulatory, clinical and operational objectives (e.g., launch of Amtagvi), with company‑wide payout calibration by level; 2024 VP+ payouts were 50% of target based on goal attainment (illustrative of framework, not specific to Kirby) .

Equity Ownership & Alignment

  • Beneficial ownership (direct/indirect shares, options exercisable) for Kirby was not disclosed in the 2025 proxy’s record‑date ownership table (covers 2024 NEOs/directors; Kirby not listed) .
  • Stock ownership guidelines: Iovance does not require executives to hold a specific number of shares, but views existing holdings as adequate for alignment .
  • Hedging/pledging: Insider Trading Policy prohibits short‑selling, derivatives, margin accounts, pledging, and hedging/monetization transactions for directors and Section 16 officers, reducing misalignment and forced‑sale risks .
  • Equity plan overhang/run‑rate: 3‑year average run rate 3.71%; total overhang 10.48% as of record date; helps frame dilution context for equity awards company‑wide .

Employment Terms

  • Company practice: Written employment agreements are used for NEOs to define termination/severance and restrictive covenants, but Kirby’s specific agreement terms are not disclosed .
  • Change‑of‑control (2018 Equity Plan): If terminated other than for cause within 12 months post‑CoC, options/SARs become immediately exercisable and RSUs/restricted stock vest (performance‑conditioned awards vest based on actual/target achievement, typically prorated); committee may cash‑out awards in connection with transactions. These terms apply to awards under the 2018 Plan; Kirby’s inducement grants are under the 2021 Inducement Plan and specific CoC terms for those awards were not disclosed .
  • Clawback: Dodd‑Frank/Nasdaq‑compliant clawback policy adopted November 17, 2023; equity awards under the 2018 Plan are subject to clawback where required .

Investment Implications

  • Alignment and retention: A sizable three‑year, front‑loaded inducement package (aggregate up to 305,000 shares) creates strong near‑ to medium‑term retention hooks and aligns incentives with share‑price and commercial execution; performance‑vesting RSUs tied to financial results add pay‑for‑performance sensitivity .
  • Selling pressure cadence: Time‑based vesting (one‑third at first anniversary, then quarterly) establishes predictable potential liquidity windows; actual selling behavior should be monitored via Form 4 filings to assess insider supply signals and confidence .
  • Governance safeguards: No mandatory ownership minimums but robust prohibitions on hedging/pledging and an active clawback framework reduce alignment and reputational risk; plan‑level CoC accelerators can mitigate retention risk through transition events .
  • Execution track record: Kirby’s history spans multiple cell/oncology launches and market access for CAR‑T—directly relevant to scaling Amtagvi and Proleukin commercialization; effectiveness should be judged against Iovance’s stated commercial/regulatory objectives rather than GAAP metrics per company pay philosophy .