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Mona Ashiya

Director at Disc Medicine
Board

About Mona Ashiya

Mona Ashiya, Ph.D., is an independent Class I director of Disc Medicine (IRON), serving since September 2021; her current term expires at the 2027 annual meeting, and she is 56 years old as of April 15, 2025 . She is a Partner at OrbiMed Advisors LLC (since October 2010), with prior public board service at Sierra Oncology, Inc. (Nasdaq: SRRA) from November 2019 to July 2022; she holds a B.A. from the University of California, Berkeley and a Ph.D. in Cellular, Molecular and Developmental Biology from the University of Pittsburgh . The board has determined she is independent under SEC and Nasdaq rules, and she serves on key committees that meet independence standards .

Past Roles

OrganizationRoleTenureCommittees/Impact
Sierra Oncology, Inc. (Nasdaq: SRRA)DirectorNov 2019 – Jul 2022 Not disclosed

External Roles

OrganizationRoleTenureNotes
OrbiMed Advisors LLCPartnerOct 2010 – Present Serves on boards of several private companies (not enumerated)

Board Governance

  • Independence: Board determined Ashiya is independent; only CEO John Quisel and director Georges Gemayel are not independent . Committee independence: compensation and nominating/gov committees meet SEC/Nasdaq independence standards .
  • Committees and roles:
    • Compensation Committee: Members—Donald Nicholson (Chair), Mona Ashiya, Kevin Bitterman; met 4 times in 2024 .
    • Nominating & Corporate Governance Committee: Members—Kevin Bitterman (Chair), Mona Ashiya, Donald Nicholson, Liam Ratcliffe; met 1 time in 2024 .
    • Audit Committee: Members—William White (Chair), Liam Ratcliffe, Mark Chin; met 4 times in 2024 .
  • Board activity and attendance: Board met 4 times in 2024; every director then in office attended at least 75% of aggregate board and committee meetings; all directors attended the 2024 annual meeting .
  • Executive sessions: Four executive sessions of independent directors were held in 2024 .
  • Classification and tenure: Class I director; term expires 2027 .
  • Shareholder support signal: At the June 12, 2024 annual meeting, Ashiya received 21,799,456 votes for, 149,253 withheld, and 885,757 broker non-votes, indicating strong support .

Fixed Compensation

YearFee Earned or Paid in Cash ($)Equity/Option Awards ($)Total ($)
202449,000 282,675 (grant-date fair value under FASB ASC 718) 331,675

Non-Employee Director Compensation Policy (Cash Retainers):

RoleAnnual Retainer (Non-Chair) ($)Annual Retainer (Chair) ($)
Board of Directors40,000 150,000
Audit Committee10,000 20,000
Compensation Committee7,500 15,000
Nominating & Corporate Governance Committee5,000 10,000

Notes:

  • Director compensation emphasizes cash retainer plus equity option grants; no meeting fees disclosed for 2024 .
  • Employee directors receive no additional compensation; reasonable out-of-pocket expenses reimbursed .

Performance Compensation

Award TypeGrant SizeVestingChange-of-Control
Initial Option Grant20,000 shares Equal monthly over 3 years with 1-year cliff, subject to continued service Full acceleration upon sale of the Company
Annual Option Grant10,000 shares (each annual meeting) Vests in full by first anniversary or next annual meeting, subject to continued service Full acceleration upon sale of the Company
  • No director performance metrics disclosed; equity awards are time-based (alignment through long-term vesting) .
  • Company policies prohibit option repricing without stockholder approval (executive program practice) and prohibit hedging/pledging by employees and directors, which strengthens alignment .

Other Directorships & Interlocks

EntityNatureDetailsGovernance/Conflict Note
OrbiMed Advisors LLC affiliates5% holder (at time of June 2024 offering)Purchased 83,334 shares for $3,000,024 in June 2024 underwritten offering Ashiya is an OrbiMed Partner; related-party exposure mitigated by board policies and audit committee review of related-party transactions
AI DMI LLC (Access Industries affiliate)>5% holderPurchased 416,667 shares for $15,000,012 in June 2024 offering; holds 10.80% (incl. 204,081 pre-funded warrants) Board member Ratcliffe is Head of Biotechnology at Access Industries; independence maintained per board determination
Atlas Venture affiliates>5% holderPurchased 222,223 shares for $8,000,028 in June 2024 offering Board member Bitterman is a partner at Atlas Venture; independence maintained per board determination

Policies and Controls:

  • Related-party transactions reviewed and approved by a majority of disinterested directors; stockholder disclosure required as applicable .
  • Audit committee specifically reviews related-party transactions .

Expertise & Qualifications

  • Investing/Board Experience: Partner at OrbiMed since 2010; service on public and private boards; qualified for Disc’s board based on extensive healthcare investing and board experience .
  • Education: B.A. UC Berkeley; Ph.D. University of Pittsburgh (Cellular, Molecular & Developmental Biology) .

Equity Ownership

HolderShares Beneficially Owned (#)% of Shares OutstandingNotes
Mona Ashiya, Ph.D.24,136 <1% (of 34,632,936 shares outstanding as of Apr 15, 2025) Beneficial ownership under SEC rules includes shares issuable from options exercisable within 60 days
Unexercised Options (as of Dec 31, 2024)24,136 Aggregate number of securities underlying unexercised options held

Alignment and Risk Controls:

  • Hedging and pledging of company stock by directors are expressly prohibited by insider trading policy .
  • Director stock ownership guidelines: not disclosed in proxy .

Governance Assessment

  • Board effectiveness and independence: Ashiya is independent and sits on critical committees (Compensation; Nominating & Corporate Governance) that meet SEC/Nasdaq standards—positive for oversight .
  • Engagement signal: Strong shareholder support in 2024 director election (21.8M for; 149k withheld)—positive for investor confidence .
  • Compensation alignment: Director pay combines modest cash retainer with time-based equity; no hedging/pledging; option vesting aligns with service; equity accelerates on sale—generally standard, with single-trigger acceleration common for directors .
  • Attendance and diligence: Board met 4 times; committees active; all directors met at least 75% attendance and attended the annual meeting—supports engagement .
  • Potential conflicts/interlocks: OrbiMed affiliates participated in the June 2024 offering while Ashiya is an OrbiMed Partner; the board’s related-party approval policy and audit committee oversight mitigate risk, but continued monitoring is warranted; similar interlocks exist with AI DMI/Access Industries and Atlas Venture via other directors .
  • Ownership “skin in the game”: Beneficial ownership is <1%; while policy prohibits hedging/pledging, no director ownership guidelines are disclosed—neutral to modest alignment signal .