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Alexander Denner

Director at IRONWOOD PHARMACEUTICALSIRONWOOD PHARMACEUTICALS
Board

About Alexander Denner

Alexander Denner, Ph.D., age 55, has served on Ironwood’s board since 2020 and is the Founding Partner and Chief Investment Officer of Sarissa Capital Management LP (since 2011). He holds a B.S. in mechanical engineering from MIT and an M.S., M.Phil., and interdisciplinary Ph.D. from Yale University; prior roles include Senior Managing Director at Icahn Capital and portfolio manager at Viking Global and Morgan Stanley Investment Management. At IRWD, he chairs the Governance and Nominating Committee and is classified as an independent director under Nasdaq rules .

Past Roles

OrganizationRoleTenureCommittees/Impact
Icahn Capital LPSenior Managing Director2006–2011Activist-oriented governance oversight and capital allocation experience
Viking Global InvestorsPortfolio ManagerNot disclosedInstitutional investing experience, healthcare focus
Morgan Stanley Investment ManagementPortfolio ManagerNot disclosedAsset management expertise

External Roles

OrganizationRoleStatus/TenureCommittee/Impact
Attralus, Inc. (private)DirectorCurrentBoard oversight in biotech
The Medicines CompanyChair of the BoardWithin last five yearsLed board through strategic decisions
Sarissa Capital Acquisition Corp.Chair of the BoardWithin last five yearsSPAC governance leadership
Biogen Inc.DirectorWithin last five yearsLarge-cap pharma board experience

Board Governance

  • Committee assignments: Chair, Governance and Nominating Committee; not listed on Audit or Compensation & HR committees .
  • Independence: Board determined Denner is independent (8 of 9 directors independent); all committees comprised solely of independent directors .
  • Attendance and engagement: Board held 7 meetings in 2024; Governance & Nominating met 2 times; each incumbent director attended at least 75% of board and committee meetings; regular executive sessions of independent directors .
  • Governance processes: Annual board and committee evaluations led by Governance chair; anti-overboarding policy (≤4 public boards), hedging/pledging prohibited; stock ownership guidelines in place .

Fixed Compensation

ComponentAmountDetail
Annual Board Retainer (cash)$50,000Standard non-employee director retainer
Governance & Nominating Chair Fee (cash)$10,000Chair retainer
Cash Fees Paid (2024)$59,984Denner elected to receive retainer in vested shares instead of cash
Stock Awards (2024 grant)$138,573Annual restricted stock; vest pre-2025 annual meeting
Shares Granted (2024 annual grant)24,311$250,000 ÷ $10.28 6‑mo avg price; grant-date fair value $5.70/share

Notes:

  • Denner received 11,765 vested shares in lieu of cash fees for 2024 .
  • Director comp cap under A&R 2019 Plan: $600,000/year .

Performance Compensation

  • Non-employee directors receive time-based restricted stock; no options or PSUs; no performance metrics tied to director compensation disclosed .

Other Directorships & Interlocks

  • Compensation committee interlocks: None; no insider participation; none of Ironwood executives served on boards/comp committees of entities with Ironwood executives on IRWD’s comp committee .
  • Related party transaction oversight resides with Audit Committee; must approve transactions >$120,000 involving directors/5% holders .

Expertise & Qualifications

  • Capital allocation, strategic transactions, and risk management experience; broad healthcare industry knowledge as investor and director .
  • Academic credentials: MIT B.S.; Yale M.S., M.Phil., Ph.D. (interdisciplinary mechanical engineering) .

Equity Ownership

HolderShares% OutstandingNotes
Alexander Denner (direct)166,769~0.1%Directly held shares
Sarissa Capital Management LP16,390,00010.2%Shared voting/dispositive power; Denner is CIO; Form 4 filed Apr 4, 2025 referenced
Total beneficial (Denner + Sarissa)16,556,76910.2%Aggregated for director disclosure

Additional alignment and restrictions:

  • Director stock ownership guidelines: ≥3x annual retainer; as of Mar 31, 2025, all non-employee directors in compliance .
  • Hedging/pledging by directors prohibited; margin accounts/pledging generally prohibited .

Governance Assessment

  • Positive signals:

    • Independent status and chairing Governance & Nominating aligns with governance best practices; annual evaluations and independent-only committees support oversight quality .
    • Strong ownership alignment via significant Sarissa stake (10.2%) and director equity grant policy; stock ownership guidelines enforced .
    • Anti-hedging/pledging policy and anti-overboarding compliance reduce alignment and bandwidth risks .
    • No related-party transactions since Jan 1, 2024; robust audit committee approval protocol for any such transactions .
  • Potential conflicts and RED FLAGS to monitor:

    • Large beneficial ownership and activist background can concentrate influence; Denner chairs nominations, which may shape board refresh and governance posture—investors should monitor nomination processes and succession outcomes for independence preservation .
    • While no related-party transactions disclosed, continued vigilance warranted given Sarissa’s position; Audit Committee oversight mitigant is in place .
  • Shareholder sentiment:

    • Say-on-pay approval ~94% at 2024 annual meeting suggests investor support for overall compensation governance; not director-specific but reflects governance climate .

Insider filings context:

  • Beneficial ownership footnote references Schedule 13D/A (Mar 1, 2021) and Form 4 (Apr 4, 2025) for Sarissa/Denner holdings; shared voting/dispositive power disclosures noted .