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Margaret Ancona

Senior Vice President, Chief of Staff at MYRIAD GENETICSMYRIAD GENETICS
Executive

About Margaret Ancona

Margaret (“Maggie”) Ancona is Senior Vice President, Chief of Staff at Myriad Genetics; she joined in January 2021 after leading Global Transformation and Program Management at HP and Dell Technologies. She holds a BA in English from the University of San Francisco and is 55 years old . Company performance during her tenure includes 2024 revenue of $837.6M (+11% YoY), adjusted operating income of $21.8M, and adjusted EBITDA of $40.4M; however, Myriad’s cumulative TSR value-of-$100 stood at 49.35 at FY2024 year-end versus 116.11 for the IXHC peer index, underscoring mixed shareholder returns over the period .

Past Roles

OrganizationRoleYearsStrategic Impact
Hewlett Packard (HP)Led Global Transformation & Program ManagementNot disclosedOversaw business transformation strategy, executed large-scale programs and cost management, retooled digital infrastructure
Dell TechnologiesLed Global Transformation & Program ManagementNot disclosedBusiness transformation, large-scale program execution, digital infrastructure modernization

External Roles

No public-company directorships or external board roles are listed in her executive biography .

Fixed Compensation

  • Specific base salary, target bonus, and bonus payout amounts for Ancona are not disclosed (she is an executive officer but not a named executive officer (NEO) in the proxy) .
  • Executive compensation structure comprises annual base salary, short-term cash incentives, and long-term equity (RSUs and PSUs) .

Performance Compensation

Myriad’s executive short-term incentive (STI) program is formula-driven around four quantitative metrics plus individual MBOs; weights vary by executive, with financial metrics generally receiving the highest weight . 2024 company-level outcomes used in STI calculations:

MetricTargetActualAchievement (% of Target)Payout % (for 40%/30%/5%/5% weighting)
Revenue ($USD Millions)$830.0$837.6109%43.6%
Adjusted Operating Income ($USD Millions)$7.2$21.8150%45.0%
Employee Engagement (Percentile)77th79th107%5.4%
Customer NPS (Percentile)65th71.6th133%6.7%

PSU design emphasizes three-year performance on revenue, adjusted EPS, and relative TSR vs IXHC; maximum payout is capped at target if absolute TSR is negative . The 2022 PSU cycle paid at 66% of target (revenue 98%, adjusted EPS 0%, relative TSR 100% capped due to negative absolute TSR) .

Equity Ownership & Alignment

  • Stock ownership guidelines: CEO 6x salary; COO/CCO/CFO 3x; other executive officers (including Chief of Staff) 2x; must hold 50% of net shares acquired until guideline compliance; RSUs count toward compliance; PSUs/options do not .
FeatureGuidelines
Ownership MultipleCEO 6x; COO/CCO/CFO 3x; Other Executive Officers 2x base salary
Years to MeetFive years from appointment or adoption
Shares That CountCommon stock and time-based RSUs; excludes unexercised options and unvested PSUs
Transfer RestrictionsMust hold 50% of net shares from vesting/exercise until guideline met; post 5-year phase-in, sales prohibited until met (tax sales excluded)
Compliance StatusAs of Dec 31, 2024, all directors and executive officers were in compliance or have time remaining in the five-year phase-in
  • Hedging/pledging: Prohibited for all directors, officers, and employees; no margin or collateral pledging of company stock .
  • Beneficial ownership: The proxy provides detailed ownership for NEOs and directors; Ancona’s specific share count is not disclosed .

Standard vesting mechanics for executives:

Award TypeVestingNotes
RSUsPro-rata over 3 years (typically 33.3% annually)Granted annually; minimum one-year vesting policy
PSUsCliff vest at 3 yearsEarned based on revenue, adjusted EPS, and relative TSR vs IXHC; capped at target if absolute TSR negative

Employment Terms

Myriad has standard employment agreements with executive officers and separate Severance and Change-of-Control (CoC) Agreements (Diaz/CEO had distinct terms; others share the standard terms) .

ProvisionStandard Execs (incl. Chief of Staff)Citation
CoC threshold50% ownership/voting power; specified merger/asset sale; board change
Equity acceleration (non-CoC)Immediate vesting of RSUs scheduled within 2 years; PSUs vesting tracked for 2 years to extent metrics achieved
Equity acceleration (CoC + qualifying termination)Immediate full vesting of all unvested equity awards
Severance multiple (non-CoC)1x salary + target bonus; prorated current-year bonus; up to 12 months COBRA (Raha had higher terms as incoming CEO)
Severance multiple (CoC + qualifying termination)1x salary + target bonus; immediate equity vesting; up to 12 months COBRA (Raha higher as CEO)
TriggersDouble-trigger structure (CoC and termination without cause/for good reason)
ClawbackMandatory recoupment for restatements; covers cash incentives, RSUs, PSUs, stock-price/TSR-linked metrics over prior 3 years

Performance & Track Record (Company context during Ancona’s tenure)

MetricFY 2021FY 2022FY 2023FY 2024
Revenue ($USD Millions)690.6 678.4 753.2 837.6
Net Income (Loss) ($USD Millions)(27.2) (112.0) (263.3) (127.3)
TSR – $100 initial value99.35 52.23 68.90 49.35

Additional 2024 highlights: revenue +11% YoY to $838M, adjusted operating income $21.8M, adjusted EBITDA $40.4M, adjusted EPS $0.14; STI revenue and adjusted operating income paid at 109% and 150% of target respectively . Say-on-pay 2024 approval was 95%, indicating shareholder support for pay program design .

Compensation Structure Analysis

  • Equity-heavy and performance-linked: 50% of annual equity is PSUs with objective metrics (revenue, adjusted EPS, relative TSR); absolute TSR cap prevents outsized payouts in down markets .
  • Governance safeguards: Anti-hedging/pledging; no option repricing; no single-trigger equity vesting; independent consultant (Mercer) and peer benchmarking underpin decisions .
  • Ownership alignment: Elevated guideline multiples plus 50% holding requirement until compliance supports long-term alignment and dampens near-term selling pressure .

Risk Indicators & Red Flags

  • Pledging/hedging: Prohibited—a positive alignment feature .
  • Equity modification/repricing: Disallowed without shareholder approval; no repricing policy stated .
  • Clawbacks: Robust SEC/Nasdaq-compliant clawback policy across incentive pay—mitigates restatement risk .
  • Program integrity: CHCC did not lower or adjust 2024 metrics; performance PSUs paid at 66% for 2022 cycle, evidencing at-risk nature .

Compensation Peer Group (Benchmarking context)

Mercer-reviewed 2024 peer group includes diagnostics/biotech names such as Exact Sciences, Natera, Veracyte, Bio-Techne, Neurocrine, and others; this peer set informs market calibration for salaries, STI, and LTI grants .

Equity Ownership & Insider Selling Pressure (Implications)

  • Standard RSU/PSU vesting creates periodic supply; however, executives must hold 50% of net shares until meeting ownership multiples, tempering sales at vest events .
  • Without Form 4 data in the proxy, specific insider transactions for Ancona are not disclosed here; monitoring Section 16 filings is advised for sell/buy patterns and vest-driven activity .

Employment Terms (Retention & Transition)

  • Double-trigger CoC protection and 1x salary+bonus severance (with two-year equity acceleration in non-CoC terminations) provide downside protection but are not excessive vs mid-cap diagnostics peers, balancing retention and shareholder interests .

Investment Implications

  • Pay-for-performance alignment is strong: formulaic STI tied to revenue and adjusted operating income, and PSU mix with revenue/adjusted EPS/relative TSR, all under governance guardrails and clawbacks—supporting confidence in execution incentives .
  • Alignment and selling pressure: Elevated ownership guidelines and 50% holding requirements reduce near-term disposition risk at vest dates; anti-pledging further mitigates leverage-driven sales .
  • Retention risk appears moderate: Standard severance and double-trigger CoC terms for executive officers provide stability without outsized entitlements, though two-year equity acceleration on non-CoC termination can influence exit calculus .
  • Performance context: Revenue growth and positive adjusted profitability metrics in 2024 are offset by weak multi-year TSR vs IXHC; continued delivery against financial targets (including PSU metrics into 2026–2027) will be pivotal for value creation and payout realizations .