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David Lacey

Director at Nurix Therapeutics
Board

About David Lacey

David L. Lacey, M.D. (age 72) is an independent director of Nurix Therapeutics, serving since April 2016; he previously served as Chairman of the Board from August 2019 to May 2024 . A biopharmaceutical consultant since 2011 (David L. Lacey LLC), he advises academic institutions, biotech companies, and venture firms, and currently sits on the boards of Arcus Biosciences, Inc. and Inbiomotion SL; earlier in his career he held senior roles at Amgen, including SVP of Discovery Research (1994–2011) . He holds a B.A. in Biology from University of Colorado, Denver, and an M.D. from the University of Colorado School of Medicine, with core credentials in drug discovery leadership and managing large research organizations .

Past Roles

OrganizationRoleTenureCommittees/Impact
Nurix Therapeutics (NRIX)Chairman of the BoardAug 2019 – May 2024Led board oversight during growth and clinical development phases
Amgen Inc.SVP, Discovery Research1994 – 2011Led drug discovery; managed large R&D organization

External Roles

OrganizationRoleTenureCommittees/Impact
Arcus Biosciences, Inc.DirectorCurrentNot disclosed in NRIX proxy
Inbiomotion SLDirectorCurrentNot disclosed in NRIX proxy

Board Governance

  • Independence: Board determined Dr. Lacey is independent under SEC and Nasdaq rules; 8 of 9 incumbent directors were independent as of March 21, 2025 .
  • Committee assignments:
    • Compensation Committee: Chair (core responsibilities include executive and director pay oversight; engaged independent consultant Aon; no conflicts identified) .
    • Clinical & Commercialization Committee: Member (oversight of clinical development and commercialization risks) .
  • Meeting cadence and attendance: FY2024 Board met 5 times; Audit 5; Compensation 6; Nominating & Corporate Governance 5; Development Advisory/Clinical & Commercialization 6; no director attended fewer than 75% of aggregate Board and committee meetings during their tenure .
  • Board leadership: CEO and Chair roles separated (Chair: Julia P. Gregory), enhancing oversight independence .
  • Executive sessions: Independent directors meet separately without management on a regular basis .

Fixed Compensation

ComponentAmount ($)Notes
Annual Director Cash Retainer50,000Paid quarterly in arrears
Additional Cash – Board Chair35,000Not applicable to Lacey in FY2024 post-May 2024; program detail
Additional Cash – Committee Chair (Audit/Comp/NomGov/Clinical)15,000 / 10,000 / 10,000 / 10,000Compensation Committee chair: 10,000 (Lacey)
Additional Cash – Committee Member (Audit/Comp/NomGov/Clinical)7,500 / 5,000 / 5,000 / 5,000Clinical & Commercialization member: 5,000 (Lacey)
YearFees Earned/Paid ($)Option Awards ($)Total ($)
2023100,000 163,285 263,285
202479,583 276,179 355,762

Notes:

  • Program unchanged from prior year; non-employee directors reimbursed for reasonable expenses .
  • Lacey’s lower FY2024 cash vs FY2023 is consistent with stepping down from the Board Chair role in May 2024 .

Performance Compensation

Grant TypeSharesVestingPerformance Metrics Tied to Director Pay
Initial Director Option Grant50,00036 equal monthly installments; fully vested at 3 years, service-based None disclosed for directors
Annual Director Option Grant25,0001-year cliff; vests at next annual meeting or 1-year anniversary, service-based None disclosed for directors
  • Option awards reflect ASC 718 grant-date fair value; accounting cost does not equal realized value .

Other Directorships & Interlocks

CompanyRoleInterlocks/Relationships with NRIX
Arcus Biosciences, Inc.DirectorNo related-party transactions disclosed involving Lacey
Inbiomotion SLDirectorNo related-party transactions disclosed involving Lacey
  • Policy: Audit Committee reviews and must approve any related person transactions >$120,000; none reported from Dec 1, 2023 to present (other than director/NEO compensation) .

Expertise & Qualifications

  • Extensive drug discovery leadership and large-scale R&D management experience from Amgen; active advisory roles across biotech .
  • Medical and scientific training (M.D.), with board tenure since 2016 and prior Board Chair experience, aligning with complex clinical and commercialization oversight needs .

Equity Ownership

HolderBeneficial Ownership (Shares)% of OutstandingAs-of Date
David L. Lacey, M.D.184,999 <1% (asterisk) March 21, 2025
Outstanding Options Held (as of 11/30/2024)Count
Lacey Option Awards (#)151,666
  • Ownership computed under SEC rules (includes options exercisable within 60 days and RSUs vesting within 60 days) .
  • No pledging or hedging disclosures specific to Lacey; company maintains a Code of Business Conduct and Ethics and insider trading provisions (policy oversight under Audit Committee) .

Governance Assessment

  • Strengths:

    • Independent director; confirmed by Board’s annual independence review .
    • Chair of Compensation Committee with use of independent consultant (Aon) and explicit conflict-of-interest review; no consultant conflicts identified .
    • Active committee service in Clinical & Commercialization oversight; aligns with his Amgen R&D leadership background .
    • Attendance: No director below 75% of aggregate meetings; Board and committees met regularly (5–6 meetings) indicating engagement cadence .
    • Separation of Chair and CEO roles supports independent oversight; Lacey signed the Compensation Committee report, evidencing engagement in executive pay governance .
  • Potential Risks/Red Flags:

    • Multiple external board roles (Arcus; Inbiomotion) may raise time-commitment considerations, though NRIX’s Corporate Governance Guidelines require directors to devote adequate time and consider outside commitments in nominations; no attendance shortfall disclosed .
    • No related-party transactions disclosed; mitigates conflict risk .
  • Compensation Alignment Signals:

    • Director pay structure tilted toward service-based options (Initial and Annual grants), aligning director incentives with shareholder value without short-term performance metrics that could bias oversight .
    • Year-over-year mix shows higher FY2024 option fair value vs FY2023 and lower cash (consistent with change in chair status), avoiding excessive guaranteed cash .