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Hans van Houte

Chief Financial Officer at Nurix Therapeutics
Executive

About Hans van Houte

Hans van Houte, age 59, is Chief Financial Officer of Nurix Therapeutics (NRIX), serving as CFO since June 2020 after leading the company’s finance team since 2015; he holds a B.S. in Business Administration (Finance and Accounting) from Babson College and previously held senior finance roles in biotech including Vertex and Trubion . During his tenure, company TSR (value of an initial fixed $100 investment) improved to 76.72 in FY2024 from 21.58 in FY2023, and 42.99 in FY2022, while net income remained negative at -$194M in FY2024 (vs. -$144M FY2023 and -$180M FY2022) .

Past Roles

OrganizationRoleYearsStrategic Impact
Bionation LLCManaging Partner; acted as CFO for multiple biotech companiesNot disclosedProvided executive-level finance leadership as acting CFO for multiple biotechnology companies
Trubion Pharmaceuticals, Inc.Vice President, Finance & OperationsNot disclosedSenior finance and operations leadership at a biotechnology company
Vertex Pharmaceuticals IncorporatedController, Treasurer, Principal Accounting OfficerNot disclosedCorporate accounting and treasury leadership at a global biotechnology firm

External Roles

  • No current public-company directorships or external board roles disclosed in the executive officer biography .

Fixed Compensation

MetricFY 2022FY 2023FY 2024
Base Salary Rate ($)$484,100 $500,000
Salary Paid ($)$465,417 $482,925 $498,675
Target Bonus % of Base40% 40% 40%
Actual Bonus Paid ($)$171,080 $193,640 $230,000
All Other Compensation ($)$14,244 $5,418 $4,460

Notes:

  • Base salary rate reflects annualized rates; salary paid reflects actual amounts recognized in the Summary Compensation Table .
  • Target bonus % unchanged at 40% across periods .

Performance Compensation

Metric CategoryWeightingTargetActualPayout ($)Vesting
Corporate performance (clinical, research, business goals)70% 100% of target115% of target $230,000 total payout with corporate multiplier applied N/A (cash)
Individual performance (non-CEO NEOs)30% 100% of target115% of target Included in total payout above N/A (cash)

Program design highlights:

  • Corporate goals (unweighted) spanned advancing NX‑5948/NX‑2127/NX‑1607 trials, collaboration milestones (Sanofi, Gilead, Pfizer), and cash runway/engagement; achievement was determined at 115% of target for 2024 .
  • Non-CEO NEO individual performance multiplier set at 115% for 2024 based on contributions to corporate goals .

Equity Ownership & Alignment

ItemValue/Detail
Total beneficial ownership535,863 shares (33,724 common; 8,636 RSUs settleable within 60 days of Mar 21, 2025; 493,503 options exercisable within 60 days)
Ownership as % of shares outstanding<1% of 76,235,594 shares outstanding (as of Mar 21, 2025)
Stock ownership guidelinesNot disclosed in proxy
Hedging/pledging policyHedging prohibited; pledging prohibited absent pre-approval; bans derivative transactions
Clawback policyCompensation recovery policy adopted July 2023, compliant with SEC/Nasdaq; applies to incentive-based compensation on accounting restatements
Insider activity (FY2024)RSUs vested: 27,044 shares ($502,966 realized); no option exercises

Equity Grants and Vesting (Selected 2024 Awards)

Award TypeGrant DateShares/UnitsExercise PriceExpirationVesting ScheduleStatus at FY-endMarket Value (FY-end)
Stock Options2/13/2024 150,000 $8.72/share 2/12/2034 1/36 monthly over 36 months 37,500 exercisable; 112,500 unexercisable as of 11/29/2024 N/A
RSUs2/13/2024 45,000 N/AN/AQuarterly over 3 years; first vest 7/30/2024 37,500 units unvested as of 11/29/2024 $829,125 at $22.11/share

Other outstanding awards (prior years) include RSUs granted 1/19/2022 (vest quarterly over 4 years) and 2/14/2023 (vest quarterly over 3 years) .

Employment Terms

ScenarioCash SeveranceHealthcare ContinuationEquity VestingTotal (as of 11/30/2024)
Termination without cause / for good reason (outside change-of-control period)0.75× base salary ($375,000) plus any prior-year earned bonus (paid separately) 9 months continuation ($23,012) No acceleration$398,012
Termination without cause / for good reason (within 12 months post-change-of-control)Base salary + target bonus ($700,000) plus prior-year earned bonus (paid separately) 12 months continuation ($30,683) Full acceleration of time-based awards; performance awards per plan $4,337,323 (includes $3,606,639 accelerated equity value)
Equity not assumed by successor in change-of-controlAutomatic full acceleration regardless of termination Full acceleration

Additional terms:

  • Double-trigger required for cash severance in change-of-control; 280G “best-net” cutback applies to parachute payments .
  • Definitions of “cause” and “good reason” set forth in Executive Severance Plan; cure and notice periods apply .
  • NEOs are at-will; severance plan supersedes prior agreements regarding severance/equity acceleration .

Compensation Committee & Benchmarking

  • Compensation Committee (independent directors) oversees executive pay and engaged Aon’s Human Capital Solutions as independent consultant; no conflicts identified .
  • 2024 peer group (23 pre-commercial biotech companies) used for benchmarking (e.g., Arcus, Arvinas, C4, Kymera, Relay, Revolution Medicines, Tango, Zentalis) .
  • 2024 Say-on-Pay approval: ~88.3% “For” .

Compensation Structure Analysis

  • Pay mix emphasizes variable, at-risk pay: non-CEO NEO target pay with 75% at-risk in 2024 (mix of cash bonus and equity) .
  • Shift toward retention-focused RSUs for non-CEO NEOs (30% of LTI), alongside options (70% of LTI) to balance alignment and retention; options have 10-year terms, at-market strikes, and monthly vesting .
  • Clawback compliant with SEC/Nasdaq; no excise tax gross-ups; hedging/pledging restrictions; no guaranteed compensation; no special retirement benefits .

Risk Indicators & Red Flags

  • Full acceleration of time-based equity upon change-of-control termination (and automatic acceleration if awards are not assumed) increases potential change-of-control costs and dilution risk .
  • No related-party transactions >$120,000 involving executives disclosed in FY2024; Section 16 filings deemed timely, reducing governance risk .
  • Company maintains anti-hedging/anti-pledging policy; pledging requires pre-approval—no pledges disclosed for Mr. van Houte .
  • 2025 secondary offering included lock-up provisions and permitted 10b5‑1 plans; could influence timing of insider liquidity but subject to restrictions (not specific to Mr. van Houte) .

Investment Implications

  • Incentive alignment: A balanced mix of options (upside-linked) and RSUs (retention) with meaningful annual cash bonus tied to corporate and individual milestones (115% achievement in 2024) suggests strong focus on execution of clinical and collaboration goals; cash bonus sensitivity to milestone attainment provides near-term motivation .
  • Retention risk: Material unvested equity (2024 RSUs and options) with multi-year vesting supports retention; FY2024 showed RSU vesting with no option exercises, indicating limited near-term selling pressure from options; however, change-of-control acceleration provisions could create near-term liquidity incentives in M&A scenarios .
  • Governance quality: High Say-on-Pay support (88.3%), independent committee oversight with external benchmarking, clawback compliance, and anti-hedging/pledging constraints are positives for pay-for-performance credibility .
  • Performance context: TSR improved in FY2024 alongside continued losses typical of pre-commercial biotech; compensation levers emphasize clinical progress and strategic partnerships over financial metrics, consistent with stage of development .