Earnings summaries and quarterly performance for Ovid Therapeutics.
Executive leadership at Ovid Therapeutics.
Board of directors at Ovid Therapeutics.
Research analysts who have asked questions during Ovid Therapeutics earnings calls.
Eric Schmidt
Cantor Fitzgerald & Co.
1 question for OVID
Also covers: ADCT, AGIO, BIIB +9 more
Jason Butler
JMP Citizens
1 question for OVID
Also covers: ACAD, AQST, ATHA +9 more
Sarah Weber
Piper Jaffray Companies
1 question for OVID
Tim Lugo
William Blair
1 question for OVID
Also covers: AKTX, BHVN, EYEN +3 more
Yigal Nochomovitz
Citigroup Inc.
1 question for OVID
Also covers: ALDX, APLS, ARCT +22 more
Recent press releases and 8-K filings for OVID.
Ovid Therapeutics Announces CEO Succession, Q3 2025 Financial Results, and Pipeline Updates
OVID
CEO Change
Earnings
New Projects/Investments
- Ovid Therapeutics Inc. announced a leadership succession plan, with Meg Alexander appointed Chief Executive Officer, effective January 1, 2026, succeeding Dr. Jeremy M. Levin, who will transition to Executive Chair of the Board.
- For the third quarter ended September 30, 2025, the company reported a net loss of $12.2 million, or $0.17 per share, compared to a net loss of $14.0 million, or $0.20 per share, for the same period in 2024. Revenue from royalty agreements was $132,000 for Q3 2025, down from $173,000 in Q3 2024.
- As of September 30, 2025, cash, cash equivalents, and marketable securities totaled $25.6 million. A recent private placement, with an initial closing of approximately $81 million, is expected to extend the company's cash runway into 2H 2028.
- Key pipeline updates include positive Phase 1 results for OV329, supporting advancement to a Phase 2a study in Q2 2026, and first-in-human data for OV350 anticipated in Q4 2025. The first oral KCC2 direct activator, OV4071, is expected to enter the clinic in Q2 2026.
Nov 12, 2025, 12:02 PM
Ovid Therapeutics Announces Positive OV329 Trial Results and New Securities Issuance
OVID
Convertible Preferred Issuance
New Projects/Investments
- Ovid Therapeutics Inc. announced positive topline results from its Phase 1 healthy volunteer study for OV329, a next-generation GABA-aminotransferase inhibitor being developed for drug-resistant epilepsies, on October 3, 2025.
- The study demonstrated statistically significant inhibition of GABA-AT by OV329, matching or exceeding inhibition by vigabatrin, and showed a preferable safety and tolerability profile compared to marketed anti-seizure medicines.
- Ovid plans to advance OV329 into a Phase 2a study in drug-resistant focal onset seizures and is completing a final enabling study to support regulatory filings for its oral KCC2 direct activator, OV4071, in early 2026.
- On October 2, 2025, the company entered into a Securities Purchase Agreement to sell 57,722 shares of Series B Convertible Preferred Stock and warrants to purchase a total of 67,342,325 shares of common stock.
Oct 3, 2025, 9:09 PM
Ovid Therapeutics Announces Positive Phase 1 OV329 Data and Pipeline Milestones
OVID
New Projects/Investments
Guidance Update
- Ovid Therapeutics successfully completed its Phase 1 safety and biomarker strategy for OV329, a next-generation GABA aminotransferase inhibitor, demonstrating a positive safety profile with clean ophthalmic results and target engagement.
- The company plans to initiate a Phase 2a trial for OV329 in Q2 2026, with top-line data anticipated in mid-2027 for treatment-resistant epilepsies and focal onset seizures.
- For its KCC2 program, top-line safety, tolerability, and PK data for the intravenous OV350 are expected in Q4 2025. The first oral KCC2 direct activator, OV4071, is slated for Phase 1/1b initiation in Q2 2026, with early proof of concept data in psychosis indications by Q1 2027.
- Ovid Therapeutics has sufficient resources to fund its development programs through 2028.
- The target market for OV329 in refractory and polypharmacy epilepsy and focal onset seizures represents approximately 40% of epilepsy patients and a >$1 billion commercial opportunity.
Oct 3, 2025, 12:30 PM
Ovid Therapeutics Announces Positive Topline Results for OV329 Phase 1 Study
OVID
New Projects/Investments
- Ovid Therapeutics announced positive topline results from its Phase 1 healthy volunteer study evaluating OV329, a next-generation GABA-aminotransferase inhibitor for drug-resistant epilepsies.
- The study confirmed statistically significant inhibition of GABA-AT, with OV329's inhibition matching or exceeding that demonstrated by therapeutic doses of vigabatrin.
- OV329 demonstrated a favorable safety and tolerability profile, notably showing no evidence of ophthalmic or retinal changes, which appears preferable relative to marketed anti-seizure medicines.
- Ovid plans to advance OV329 into a Phase 2a study in drug-resistant focal onset seizures, planned to initiate in Q2 2026.
- The company also provided pipeline updates, including anticipated regulatory filing for OV4071 (oral KCC2 direct activator) in Q1 2026 and topline data for OV350 (intravenous KCC2 direct activator) in Q4 2025.
Oct 3, 2025, 11:02 AM
Quarterly earnings call transcripts for Ovid Therapeutics.
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