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Carlos Paya

Chair of the Board at Vaxcyte
Board

About Carlos Paya

Carlos Paya, M.D., Ph.D. (age 66) is the independent Chairman of Vaxcyte’s Board, serving since October 2021. He is a Venture Partner at Abingworth (Carlyle), chairs Highlight Therapeutics, and serves as Senior Advisor to Ysios Capital and Launch Therapeutics. Previously, he was Chair and director at Standard BioTools (2017–2024), a director at Mallinckrodt (2019–2022), President/CEO/Director of Immune Design (2011–2019), President of Elan (2008–2011), and VP at Eli Lilly (2001–2008); earlier he was a professor and vice dean at Mayo Clinic. He holds M.D. and Ph.D. degrees from the University of Madrid and completed postdoctoral training at Institut Pasteur, Paris .

Past Roles

OrganizationRoleTenureCommittees/Impact
Standard BioTools, Inc.Director; Chairman (from May 2020)Mar 2017 – Jan 2024Led Board through merger with SomaLogic in Jan 2024
Mallinckrodt PharmaceuticalsDirectorMay 2019 – Jun 2022Board oversight during restructuring cycle
Immune Design Corp.President, CEO, DirectorMay 2011 – May 2019Led sale to Merck in 2019
Elan CorporationPresidentNov 2008 – Apr 2011Corporate leadership pre-acquisition by Perrigo
Eli Lilly & CompanyVice President, Lilly Research LaboratoriesSep 2001 – Nov 2008Senior R&D leadership
Mayo ClinicProfessor of Medicine/Immunology/Pathology; Vice Dean (Clinical Investigation)Jan 1991 – Aug 2001Academic leadership and research

External Roles

OrganizationRoleSince
Abingworth (Carlyle)Venture PartnerJan 2020
Highlight Therapeutics S.L.Chairman, Board of DirectorsJan 2020
Ysios CapitalSenior AdvisorOngoing
Launch TherapeuticsSenior AdvisorOngoing

Board Governance

  • Board leadership: Independent Chairman (separate from CEO); Board affirms this structure provides balanced oversight .
  • Independence: Board determined Dr. Paya is independent under Nasdaq standards .
  • Committees: Not listed as member or chair of Audit, Compensation, or Nominating & Corporate Governance Committees in 2024; serves as Board Chair .
  • Meetings and attendance: Board met 10 times in 2024; each current director attended at least 75% of Board and applicable committee meetings .
  • Stock ownership guidelines: Directors must hold stock equal to 4x annual cash retainer within five years; as of Dec 31, 2024, all directors were compliant or within the phase-in period .
  • Anti-hedging/pledging: Insider Trading Policy prohibits hedging and pledging, with limited pre-approved exceptions .

Fixed Compensation

2024 non-employee director compensation for Dr. Paya:

ComponentAmount (USD)
Fees Earned (Cash)$82,500
Stock Awards (Grant-date fair value)$112,391
Option Awards (Grant-date fair value)$330,130
Total$525,021

Non-employee director program (effective April 1, 2024):

  • Cash retainers: Board Chair $85,000; Board member $50,000; Audit Chair $20,000/Member $10,000; Compensation Chair $15,000/Member $7,500; Nominating Chair $10,000/Member $5,000 .
  • Equity: Initial option grant with $800,000 value; annual equity grant $450,000 (75% option, 25% RSU); annual option vests monthly to next AGM, RSUs vest by first anniversary/next AGM; full vesting on change-in-control subject to service .
  • Note: Chair retainer rose from $75,000 to $85,000 (and member retainer from $40,000 to $50,000) effective April 1, 2024, lifting fixed cash vs. 2023 levels .

Performance Compensation

  • Non-employee directors do not have performance-based cash metrics; equity grants are time-based with service-vesting and change-in-control vesting provisions per policy .
  • Dr. Paya’s outstanding awards at 12/31/2024: 1,550 stock awards; 71,000 options .

Other Directorships & Interlocks

CompanyTypeStatusNotes
Standard BioTools, Inc.PublicFormer Director; Chair through May 2020–Jan 2024Ended service upon merger with SomaLogic
Mallinckrodt PharmaceuticalsPublicFormer Director2019–2022
Immune Design Corp.Public (acquired)Former President/CEO/DirectorAcquired by Merck in 2019
  • Compensation Committee interlocks: None reported for the committee (members are independent; no officer interlocks) .
  • Related-party transactions: Proxy details policies and indemnification; no specific related-person transactions disclosed involving Dr. Paya since Jan 1, 2024 .

Expertise & Qualifications

  • Skills matrix indicates Dr. Paya brings strengths across Audit/Accounting, Business Operations, Drug Development, Executive Leadership, Finance/Capital Markets, M&A, Operations/Supply Chain, Risk Management, Scientific Research, Stakeholder/IR, Strategic Planning, and Public Company Director/Executive experience .

Equity Ownership

MetricValue
Beneficial Ownership (shares)76,020 (<1%)
Shares exercisable/vestable within 60 days (included above)70,395
Holding structureIncludes holdings via a revocable trust of which Dr. Paya is sole trustee
Ownership guidelinesDirectors must maintain 4x retainer; all directors compliant or within phase-in as of 12/31/2024
Pledging/HedgingProhibited under Company policy (limited exceptions with approval)

Governance Assessment

  • Positive signals:

    • Independent Chair structure with clear separation from CEO role enhances oversight .
    • Independence affirmed; strong attendance record standard met by all directors in 2024 .
    • Material equity component in director pay and ownership guidelines support alignment with shareholders .
    • Anti-hedging/pledging policy reduces alignment risks .
    • Say-on-pay (company-wide) received 92% support in 2024, indicating general investor confidence in governance/compensation practices .
  • Watch items / potential conflicts:

    • Multiple external roles in life sciences investing and company advising (Abingworth/Carlyle, Ysios, Launch Therapeutics) could present situational conflicts; however, no related-person transactions involving Dr. Paya are disclosed in the proxy .
    • Fixed director retainers increased in 2024 (Chair +$10k; Member +$10k); while not unusual for late-stage biotech scale-up, it modestly shifts mix toward guaranteed cash .
  • Committees:

    • As Board Chair, Dr. Paya does not serve on standing committees; committee independence and composition otherwise meet Nasdaq/SEC standards .