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Olivier Brandicourt

Director at Vaxcyte
Board

About Olivier Brandicourt

Olivier Brandicourt, M.D., is an independent Class III director of Vaxcyte (PCVX) appointed on May 1, 2025. He is a former CEO of Sanofi and Bayer HealthCare, and a long-time Pfizer executive, with medical training in Infectious Diseases and Tropical Medicine; he holds a Master’s in Biology and an advanced degree in cellular/immunological pathophysiology and is an Honorary Fellow of the Royal College of Physicians (London) . His term runs to the 2026 annual meeting, and he entered standard Vaxcyte indemnification at appointment .

Past Roles

OrganizationRoleTenureCommittees/Impact
Sanofi S.A.Chief Executive Officer2015–2019Advanced vaccine portfolio via acquisition of Protein Sciences (recombinant influenza)
Bayer HealthCare AGChief Executive Officer2013–2015Global healthcare leadership
Pfizer Inc.Exec. Leadership Team; President & GM, Emerging Markets; President, Established Products; Head, Global Specialty; Head, Global Primary Care~13 yearsCommercial strategy and execution in vaccines and global markets

External Roles

OrganizationRoleStartNotes
Blackstone Life SciencesSenior AdvisorCurrentStrategic advisory
Alnylam Pharmaceuticals, Inc.DirectorCurrentPublic biotech board
AvenCell Therapeutics, Inc.DirectorCurrentPrivate biotech board
BeOne Medicines Ltd.DirectorCurrentPrivate company board
Dewpoint Therapeutics, Inc.DirectorCurrentPrivate biotech board
National Committee on U.S.-China RelationsDirectorSince 2012Non-profit governance

Board Governance

  • Appointment and independence: Appointed May 1, 2025; Board determined he qualifies as an independent director under Nasdaq 5605(a)(2); no related-party transactions requiring Item 404(a) disclosure .
  • Class/Term: Class III; term expires at the 2026 annual meeting .
  • Committees: As of appointment, no committee assignments disclosed. Current committee rosters are Audit (Chair: Teri Loxam; members: Halley Gilbert, Jacks Lee), Compensation (Chair: Annie Drapeau; members: John Furey, Peter Hirth until June 2025, Heath Lukatch), Nominating & Corporate Governance (Chair: Halley Gilbert; members: Annie Drapeau, Peter Hirth until June 2025) .
  • Board activity: Board met 10 times in 2024; each director (then-serving) attended ≥75% of Board/committee meetings during their service portion in 2024 .
  • Governance policies: Directors subject to stock ownership guidelines; prohibition on pledging/hedging of company stock per Insider Trading Policy; Corporate Governance Guidelines posted on investor site .

Fixed Compensation

ComponentAmountNotes
Annual cash retainer (Board member)$50,000Pro-rated for partial year; increased from $40,000 as of April 1, 2024
Committee member feesAudit $10,000; Compensation $7,500; Nominating $5,000If assigned; annual
Committee chair feesAudit $20,000; Compensation $15,000; Nominating $10,000If assigned; annual
Board Chair retainer$85,000For chair; not applicable to Brandicourt

Performance Compensation

EquityValueVestingTerms
Initial Option Grant (on appointment)$800,000 equivalent1/3 on 1-year anniversary; remainder monthly over 36 monthsNonstatutory stock option under 2020 Plan
Annual Grant (each annual meeting)$450,000 equivalentOptions vest monthly; RSUs fully vest by 1-year or prior to next annual meeting75% option (Annual Option Grant); 25% RSU (Annual RSU Grant)
Change-in-control accelerationFull vesting of Initial and Annual Grants upon change in controlRequires continuous service through eventApplies to non-employee directors

Performance Metrics Table (Director Equity Structure)

Metric TypeMetricTrigger/TargetOutcome Linkage
Tenure-basedTime vesting12–36 months schedulesAligns with sustained board service
Event-basedChange-in-controlTransaction occurrenceAccelerated vesting upon CoC
ProhibitionsHedging/PledgingPolicy bans hedging/pledgingAlignment with shareholder interests

Other Directorships & Interlocks

CompanyRelationship to PCVXPotential Overlap
Alnylam Pharmaceuticals (public)Biopharma; no disclosed PCVX transactionsBoard interlock only; no 404(a) related transactions at PCVX
AvenCell Therapeutics (private)Biotech; no disclosed PCVX transactionsBoard interlock only
BeOne Medicines (private)Biotech; no disclosed PCVX transactionsBoard interlock only
Dewpoint Therapeutics (private)Biotech; no disclosed PCVX transactionsBoard interlock only
  • Vaxcyte states there are no transactions with Brandicourt requiring Item 404(a) disclosure; independence affirmed .

Expertise & Qualifications

  • Deep commercial and operational leadership in vaccines markets (Sanofi CEO; Pfizer Emerging Markets/Established Products/GPS/Primary Care) .
  • Medical specialization in Infectious Diseases & Tropical Medicine; advanced degrees in biology/immunopathophysiology; Honorary Fellow of RCP (London) .
  • Strategic advisory experience (Blackstone Life Sciences) and multiple biotech boards spanning modalities relevant to vaccines and therapeutics .

Equity Ownership

FilingDateTitle/InstrumentAmountNotes
Form 3 (initial ownership)May 2, 2025Common stock0No securities owned at filing; option grant terms per 8-K
Power of Attorney (Section 16 filings)Apr 18, 2025POA executedAuthorizes company and counsel to file Forms 3/4/5
  • Stock ownership guidelines: Non-employee directors must hold a fixed-share target equal to 4x annual cash retainer; compliance expected within five years; performance awards/options don’t count toward guideline until earned/exercised . As a 2025 appointee, Brandicourt is within the phase-in period .
  • Policy prohibits pledging and hedging of company stock .

Governance Assessment

  • Positive signals:
    • Independence confirmed; no related-party transactions per Item 404(a) at appointment .
    • Strong vaccine-market expertise, relevant to PCVX commercialization plans; complements board skill matrix (manufacturing, development, global operations) .
    • Clear, transparent director pay structure with equity/time-vesting and CoC treatment; stock ownership guidelines enhance alignment .
  • Watch items:
    • Multiple external boards and advisory role could create time-allocation risk; no PCVX-disclosed conflicts, but monitor future related-party transactions and committee assignments for potential interlocks .
    • Say-on-pay results show meaningful dissent in 2025 (For 77,119,045; Against 43,969,206; Abstain 26,117), suggesting investors scrutinize compensation practices; board (including independent directors) should continue engagement and responsiveness .

Director Compensation Context (Board-wide, 2024–2025)

Item2024/Program DetailNotes
Cash retainersBoard member $50,000; Committee member $5,000–$10,000; Committee chair $10,000–$20,000; Board chair $85,000In effect from April 1, 2024
Annual equity$450,000 (75% options; 25% RSUs)One-year vesting cadence
Initial equity for new directors$800,000 option36-month vesting
ExpensesOrdinary travel reimbursedStandard practice

Shareholder Feedback Snapshot (2025 Annual Meeting)

ProposalForAgainstAbstainBroker Non-Votes
Class II director electionsSee counts per nomineeSee table
Deloitte ratification (2025 audit)124,849,714245,36224,285
Say-on-pay (NEO comp)77,119,04543,969,20626,1174,004,992
Officer exculpation charter amendment112,270,0398,815,78828,5414,004,992
Source: Item 5.07 8-K (June 17, 2025) .

Insider Trades

FilingDateTransactionShares/DerivativesResulting Ownership
Form 3May 2, 2025Initial statementNo securities owned0 common; derivative awards to be granted per 8-K

Potential Conflicts & Related-Party Transactions

  • The company disclosed no transactions with Brandicourt reportable under Item 404(a) at appointment, and affirmed independence under Nasdaq rules .
  • Insider Trading Policy prohibits pledging/hedging; exceptions require approval and compliance with law .
  • Sublease arrangement with CARGO Therapeutics was specifically considered for another director’s independence and did not affect independence; illustrates board’s conflict review rigor .

Implications for Board Effectiveness and Investor Confidence

  • Brandicourt’s vaccine-market commercialization experience and medical background strengthen oversight of PCVX’s adult/infant PCV Phase 3 path and manufacturing scale-up, aligning with board needs .
  • Transparent compensation structure and ownership guidelines support alignment; however, 2025 say-on-pay dissent underscores the importance of continued pay-for-performance rigor and investor outreach led by independent directors .

RED FLAGS to monitor

  • Time demands from multiple external board roles (monitor attendance and committee workload once assignments are made) .
  • Any future related-party transactions arising from external affiliations (ensure continued Item 404(a) compliance and committee independence) .