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    Pfizer Inc (PFE)

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    Pfizer Inc. is a global biopharmaceutical company dedicated to the discovery, development, manufacture, marketing, sale, and distribution of biopharmaceutical products worldwide . The company operates primarily through its Biopharma segment, which significantly contributes to its total revenues . Pfizer's product offerings include major products like Comirnaty and Paxlovid, alongside other notable products such as Eliquis, the Prevnar family, and the Vyndaqel family .

    1. Biopharma Segment - Focuses on the development and commercialization of biopharmaceutical products, contributing significantly to the company's revenues.
      • Oncology - Includes products like Ibrance, Xtandi, and Inlyta, aimed at treating various types of cancer .
      • Primary Care - Features products such as Eliquis, the Prevnar family, and Paxlovid, addressing common health conditions .
      • Specialty Care - Offers products like Xeljanz and the Vyndaqel family, targeting specific medical needs .
    2. Pfizer Ignite - Engages in business development activities, including acquisitions and collaborations, to enhance the product pipeline and market presence .
    3. PC1 - Involves other business activities that support the company's overall operations .
    NamePositionExternal RolesShort Bio

    Albert Bourla

    ExecutiveBoard

    Chairman and CEO

    None mentioned

    Chairman since January 2020 and CEO since January 2019. Has been with Pfizer for decades, leading strategic transformations and vaccine development.

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    Aamir Malik

    Executive

    Chief U.S. Commercial Officer and EVP

    None mentioned

    Joined Pfizer in 2021. Leads U.S. commercial operations.

    Alexandre de Germay

    Executive

    Chief International Commercial Officer and EVP

    None mentioned

    Joined Pfizer in December 2023. Previously CEO of Laboratoires Majorelle and held leadership roles at Sanofi.

    Chris Boshoff

    Executive

    Chief Scientific Officer and President, R&D

    None mentioned

    Joined Pfizer in 2017. Recently appointed Chief Scientific Officer effective January 2025.

    David M. Denton

    Executive

    CFO and EVP

    Director of Haleon plc

    CFO since May 2022. Previously CFO at Lowe’s Companies and CVS Health.

    Douglas M. Lankler

    Executive

    General Counsel and EVP

    None mentioned

    General Counsel since December 2013. Previously Chief Compliance and Risk Officer at Pfizer.

    Lidia Fonseca

    Executive

    Chief Digital and Technology Officer and EVP

    Director of Medtronic plc

    Chief Digital and Technology Officer since January 2019. Leads digital transformation and technology initiatives.

    Michael McDermott

    Executive

    Chief Global Supply Officer and EVP

    None mentioned

    Chief Global Supply Officer since January 2022. Oversees Pfizer’s manufacturing and supply chain operations.

    Mikael Dolsten

    Executive

    Chief Scientific Officer and President, R&D

    Director of Agilent Technologies, Inc. and Vimian Group AB

    Joined Pfizer in 2009. Leads R&D efforts, overseeing numerous regulatory approvals. Transitioning out of role by February 2025.

    Payal Sahni

    Executive

    Chief People Experience Officer and EVP

    None mentioned

    Joined Pfizer in 1997. Leads HR and people experience initiatives.

    Rady A. Johnson

    Executive

    Chief Compliance, Quality and Risk Officer and EVP

    None mentioned

    Chief Compliance, Quality and Risk Officer since January 2019.

    Sally Susman

    Executive

    Chief Corporate Affairs Officer and EVP

    None mentioned

    Chief Corporate Affairs Officer since January 2019. Oversees communications and public affairs.

    Dan R. Littman

    Board

    Independent Director

    Scientific Advisory Board Member at Vedanta Biosciences, Immunai, and others; Investigator at Howard Hughes Medical Institute

    Independent Director since 2018. Renowned immunologist and molecular biologist.

    Helen H. Hobbs

    Board

    Independent Director

    Investigator at Howard Hughes Medical Institute; Professor at UT Southwestern; Director of McDermott Center for Human Growth and Development

    Independent Director. Renowned geneticist and researcher.

    James C. Smith

    Board

    Independent Director

    Chairman of Thomson Reuters Foundation; Board Member of Marshall University and Brookings Institution

    Independent Director since 2014. Former CEO of Thomson Reuters Corporation.

    James Quincey

    Board

    Independent Director

    Chairman and CEO of The Coca-Cola Company; Director of US-China Business Council and Catalyst

    Independent Director since 2020. Brings expertise in business leadership and international markets.

    Joseph J. Echevarria

    Board

    Independent Director

    Chairman of The Bank of New York Mellon Corporation; Director of Unum Group; President of the University of Miami

    Independent Director since 2015. Former CEO of Deloitte LLP.

    Ronald E. Blaylock

    Board

    Independent Director

    Founder of GenNx360 Capital Partners; Director of CarMax, Inc. and W.R. Berkley Corporation; Trustee at Carnegie Hall and NYU Stern

    Independent Director since 2017. Brings expertise in private equity and investment banking.

    Scott Gottlieb

    Board

    Independent Director

    Partner at New Enterprise Associates; Director at Illumina, Aetion, Tempus, and National Resilience; Contributor to CNBC

    Independent Director since 2019. Former FDA Commissioner (2017–2019).

    Shantanu Narayen

    Board

    Lead Independent Director

    Chairman and CEO of Adobe Inc.; Vice Chairman of US-India Strategic Partnership Forum

    Independent Director since 2013. Brings expertise in technology and international business.

    Susan Desmond-Hellmann

    Board

    Independent Director

    Board Member of National Resilience, Inc. and Stand Up To Cancer; Adjunct Professor at UCSF; Member of PCAST

    Independent Director since 2020. Renowned for her expertise in medicine, healthcare, and academia.

    Susan Hockfield

    Board

    Independent Director

    Board Member of Repertoire Immune Medicines, Cajal Neuroscience, and Break Through Cancer; Member of Koch Institute at MIT

    Independent Director since 2020. Former President of MIT and renowned neuroscientist.

    1. Given that operating cash flow is significantly below typical levels this year due to timing of payments and one-time expenses, how does Pfizer plan to maintain and grow its dividend over time while also deleveraging the balance sheet to meet its gross leverage target of 3.25x?

    2. With the expected continued focus on execution to deliver in the second half, considering the seasonality of respiratory products, can you elaborate on the specific risks that might prevent Pfizer from achieving its raised revenue guidance and how you plan to mitigate them?

    3. You mentioned aiming to return to pre-pandemic operating margins on a mix-adjusted basis, excluding COMIRNATY; given that your Manufacturing Optimization Program's $1.5 billion in savings won't be fully realized until 2027, what additional measures are you taking to improve margins in the near term, especially as you head into IRA territory?

    4. Regarding the next-generation Prevnar vaccine, with competitors potentially offering higher serotype coverage, how confident are you in your ability to retain market leadership, and can you provide more specifics on the serotype coverage and timeline for your next-gen PCV candidate?

    5. Considering the importance of ELREXFIO in achieving your oncology strategy goals, and in light of a competitive market, what gives you confidence in the $4 billion opportunity, and can you share any early indicators from the launch that support this target?

    Program DetailsProgram 1
    Approval DateN/A
    End Date/DurationN/A
    Total additional amountN/A
    Remaining authorization$3.3 billion
    DetailsPart of Pfizer's capital allocation strategy, focusing on reinvesting in the business, growing dividends, and making value-enhancing share repurchases. Share repurchases are not currently a high priority compared to other strategies.
    NameStart DateEnd DateReason for Change
    KPMG LLPAt least 1942 PresentCurrent auditor

    Notable M&A activity and strategic investments in the past 3 years.

    CompanyYearDetails

    Seagen Inc.

    2023

    Pfizer acquired Seagen Inc. for $229 per share in cash, totaling an enterprise value of about $43 billion, financed partly with $31 billion in new long‐term debt. This move strengthens Pfizer’s oncology portfolio by adding Seagen’s ADC technology and four approved cancer treatments expected to contribute over $10 billion in risk-adjusted revenues by 2030.

    Global Blood Therapeutics

    2022

    Pfizer acquired Global Blood Therapeutics for $68.50 per share in cash, approximately $5.3 billion in total consideration plus $331 million for debt repayment. The acquisition reinforces Pfizer’s expansion into rare diseases by adding key assets—including Oxbryta, GBT601, and inclacumab—for addressing sickle cell disease.

    Biohaven Pharmaceuticals

    2022

    Pfizer acquired Biohaven Pharmaceuticals for $148.50 per share in cash, with a total transaction value of about $11.5 billion, including settlements for third‐party debt and preferred stock. This strategically expands Pfizer’s migraine treatment portfolio, incorporating CGRP programs such as Rimegepant and anticipating regulatory milestones for Zavegepant.

    ReViral

    2022

    Pfizer acquired ReViral for a total consideration of up to $536 million, with $436 million upfront and an additional $100 million tied to development milestones. The deal, treated as an asset acquisition, brought the antiviral asset sisunatovir and included a $426 million in-process R&D charge, enhancing Pfizer’s clinical-stage pipeline.

    Arena Pharmaceuticals

    2022

    Pfizer acquired Arena Pharmaceuticals for $100 per share in cash, totaling $6.6 billion (net $6.2 billion) while recording significant intangible assets of $5.5 billion in IPR&D and licensing. This acquisition adds a portfolio of immuno-inflammatory therapy candidates, including etrasimod, supporting a broad expansion in gastrointestinal, dermatologic, and cardiologic treatment areas.

    Recent developments and announcements about PFE.

    Earnings

    • New Earnings (Q4 2024)

      ·
      8 days ago

      Pfizer eyes $10–$15B in 2025 BD, fueling pipeline expansions. ABRYSVO dominates RSV with 50% dose share, tripling maternal uptake. Growth potential remains high even as obesity competition and IRA pressures weigh on near-term performance.

      View full earnings summary →