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Rajiv Patni

Director at Quince Therapeutics
Board

About Rajiv Patni

Rajiv Patni, M.D. is an independent director of Quince Therapeutics (QNCX), serving since February 2024; he is 56 years old as of April 16, 2025 and a member of the Compensation Committee . He earned his M.D. from the Icahn School of Medicine at Mount Sinai (accelerated B.S./M.D.), completed internal medicine residency and adult cardiology fellowship at Albert Einstein College of Medicine, and later served as an attending physician-scientist before moving into biopharma . His core credentials include senior clinical leadership across small-cap commercial-stage biotech and late-stage development, with regulatory negotiations and a track record contributing to approvals of 11 medicines across rare diseases .

Past Roles

OrganizationRoleTenureCommittees/Impact
Reata PharmaceuticalsEVP & Chief Research and Development OfficerJun 2023 – Sep 2023 (acquired by Biogen) Senior R&D leadership through acquisition; registrational and regulatory experience
Global Blood TherapeuticsChief Medical OfficerAug 2020 – Jun 2023 Led clinical strategy at commercial-stage biotech; contributed to rare disease approvals
Portola PharmaceuticalsChief Medical OfficerFeb 2020 – Jul 2020 Short-tenure CMO at public biopharma
Adamas PharmaceuticalsChief Medical OfficerJun 2015 – Jan 2020 CMO for public small-cap; late-stage neurology portfolio
Pfizer; Roche; Actelion; Ocera TherapeuticsIncreasing responsibility rolesEarly career (dates not disclosed) Translational-to-registrational studies; rare disease regulatory agency negotiation

External Roles

OrganizationRoleTenureNotes
BioXcel TherapeuticsStrategic Clinical Advisor to CEO and BoardSince Dec 2023 Advisory role (not a director) at public biopharma

Board Governance

  • Independence: Board determined all non-management directors (including Patni) are independent under Nasdaq; all audit, compensation, and nominating committee members satisfy SEC/Nasdaq independence requirements .
  • Committee assignments: Compensation Committee member; the Compensation Committee is composed of David A. Lamond (Chair), Margaret A. McLoughlin, Ph.D., and Rajiv Patni, M.D. .
  • Meeting cadence and attendance: In 2024, Board met 4x; Audit 4x; Compensation 3x; Nominating 2x; each director attended at least 75% of meetings of the Board and committees on which they served .
  • Lead Independent Director: Una Ryan, OBE, Ph.D., serves as Lead Independent Director with responsibilities for executive sessions, liaison duties, and stockholder communication availability .
  • Risk oversight: Board and committees oversee financial, operational, legal/regulatory, cybersecurity/privacy, and reputational risks; Audit reviews major financial risk exposures and related-party transactions; Compensation monitors compensation-related risk; Nominating oversees governance practices and independence .
  • Classified board: Three-year staggered terms; Patni stands in Class III (elected in 2025 to term ending 2028) .

Fixed Compensation

ComponentPolicy/AmountNotes
Board annual cash retainer$38,000 (member) Paid quarterly in arrears; may elect to receive in the form of a stock option beginning 1/1/2025 .
Board annual cash retainer (Lead/Chair)$52,500 (Lead/Chair inclusive of member retainer) Inclusive, not in addition, to member retainer .
Audit Committee$7,500 member; $15,000 chair Paid quarterly; independent composition .
Compensation Committee$5,500 member; $11,000 chair Committee includes Patni (member) .
Nominating & Corporate Governance Committee$4,000 member; $8,000 chair Independent composition .

Director 2024 actual compensation (Patni):

YearFees Earned/Paid in Cash ($)Stock Option Awards ($)Total ($)
202434,625 81,270 115,895

Performance Compensation

Grant DateTypeSharesExercise PriceVestingSource
Feb 15, 2024Initial director stock option under 2019 Plan54,000 $1.30 1/3 annually over 3 years, subject to service
Jun 5, 2024Annual director stock option13,500 $0.82 100% on 1-year anniversary, subject to service
Jun 4, 2025Annual director stock option27,000 $1.09 100% on 1-year anniversary, subject to service
2024 AggregateStock option awards (fair value)$81,270 aggregate grant-date fair value in 2024

Change-in-control acceleration for director options: All director stock options vest in full immediately prior to, and contingent upon, the consummation of a change in control, subject to continued service through the change in control .
Equity grant timing policy: Company indicates grant dates are predetermined and not timed around MNPI; non-employee director grants occur at initial appointment and close of business on the annual meeting date .

Other Directorships & Interlocks

  • Public company boards: None disclosed for Patni beyond QNCX .
  • External advisory engagement: Strategic Clinical Advisor at BioXcel Therapeutics (public biopharma) .
  • Related-party transactions: Company discloses related-party items since 2023; none involve Patni; 8-K confirms Patni is not party to any transaction requiring Item 404(a) disclosure .

Expertise & Qualifications

  • Medical training and clinical leadership: M.D. (Icahn School of Medicine), internal medicine and cardiology training at Albert Einstein; attending physician-scientist background .
  • Rare disease regulatory and development: Negotiations with FDA/EMA; contributed to approvals for PAH, advanced Parkinson’s, sickle cell disease, Friedrich’s ataxia; total of 11 approvals across agencies (as disclosed) .
  • Senior biopharma executive experience: CMO/CRDO roles at public companies across late-stage and commercial settings .

Equity Ownership

As-of DateShares OwnedOptions Exercisable within 60 DaysAggregate Beneficial Ownership% of Outstanding
Mar 31, 202518,000 18,000 * (based on 44,089,142 outstanding)
Dec 31, 2024 (outstanding options)67,500 options outstanding

Hedging/pledging policy: Directors are prohibited from hedging or pledging company securities and from trading publicly-traded derivatives on company stock (except compensatory awards) .

Insider Trades (Form 4)

Filing DateTransaction DateTypeSecurities TransactedExercise PriceSecurities Owned PostSecuritySEC Link
2025-06-062025-06-04Award (Director Stock Option)27,000 [1]$1.09 [1]27,000 [1]Director Stock Option (Right to Buy) [1]
2024-06-072024-06-05Award (Employee Stock Option)13,500 [2]$0.82 [2]13,500 [2]Employee Stock Option (right to buy) [2]
2024-02-152024-02-15Award (Employee Stock Option)54,000 [3]$1.30 [3]54,000 [3]Employee Stock Option (right to buy) [3]
2024-02-152024-02-15Initial Statement— [4]— [4]— [4]Form 3 [4]

Sources: Insider-trades skill output and SEC filings .

Governance Assessment

  • Strengths

    • Independence and committee service: Board has determined Patni is independent; he serves on the Compensation Committee, which is independent and oversees executive pay and human capital strategy .
    • Attendance and engagement: The Board and all committees met regularly in 2024; each director met the 75% attendance threshold, indicating engagement .
    • Alignment policies: Prohibition on hedging and pledging supports alignment with stockholders; directors may elect equity in lieu of cash retainers, increasing skin-in-the-game .
    • No related-party exposure: Company disclosure and 8-K appointment note no Item 404(a) transactions involving Patni .
  • Watch items

    • Single-trigger change-in-control vesting for director options (full acceleration immediately prior to change in control) can be perceived as reducing retention incentives post-transaction; monitor for potential governance scrutiny if combined with significant equity grants .
    • Classified board structure may impede rapid shareholder-driven board change; investors often discount staggered boards for entrenchment risk, albeit QNCX asserts continuity benefits .
  • Shareholder sentiment

    • 2025 Annual Meeting: Patni was elected with 16,270,053 votes for vs. 1,189,290 withheld; Say-on-Pay passed (16,590,485 for; 800,094 against; 68,764 abstentions) .
  • Compensation mix and ownership alignment

    • 2024 mix shows meaningful equity component ($81,270 options vs. $34,625 cash), consistent with policy to emphasize long-term alignment for non-employee directors .
    • Beneficial ownership reflects options only (18,000 exercisable within 60 days as of March 31, 2025) with no directly owned common shares disclosed; ongoing annual option grants may increase economic exposure over time .