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Daniel Welch

Chairman of the Board at Ultragenyx PharmaceuticalUltragenyx Pharmaceutical
Board

About Daniel G. Welch

Independent Chairman of the Board at Ultragenyx (RARE) since 2015; age 67. Former CEO/Chairman of InterMune and senior operator across multiple pharma roles; currently chairs Structure Therapeutics, Inc. and Prothena Corporation plc. Holds a B.S. from the University of Miami and an M.B.A. from the University of North Carolina. Board-determined independent; serves as Chairman separate from CEO, enhancing independent oversight .

Past Roles

OrganizationRoleTenureCommittees/Impact
InterMune, Inc.Chairman, CEO, President2003–2014 (CEO/President), 2008–2014 (Chairman)Led commercialization and strategy; global operating leadership
Triangle Pharmaceuticals, Inc.Chairman & CEOAug 2002–Jan 2003Oversight of strategic transition
Elan Corporation plcPresident, Pharmaceutical DivisionOct 2000–Jun 2002Global division leadership
Sofinnova VenturesExecutive PartnerJan 2015–Jan 2018Venture portfolio operations and governance

External Roles

OrganizationRoleStatusNotes
Structure Therapeutics, Inc.ChairmanCurrentPublic biotech board chair
Prothena Corporation plcChairmanCurrentPublic biotech board chair
Nuvation BioChairmanPast (Jul 2020–Sep 2024)Public biotech; stepped down 2024
Intercept Pharmaceuticals, Inc.DirectorPast (Nov 2015–Jun 2021)Public biotech
Seagen Inc.DirectorPast (Jul 2007–Dec 2023)Public biotech

Board Governance

  • Roles at Ultragenyx: Independent Chairman; member, Compensation Committee; member, Nominating & Corporate Governance Committee .
  • Independence and attendance: Board determined independent; attended 100% of Board/committee meetings in 2024 .
  • Board structure: Separate Chair and CEO; independent directors held four executive sessions in 2024; Board met four times .
  • Overboarding policy: Max five public company boards for non-CEO directors; Welch currently serves on two other public boards, within policy .
  • Clawback and trading restrictions: Company maintains clawback policy; prohibits hedging and pledging by directors .

Fixed Compensation

ItemFiscal 2024Notes
Cash fees earned$100,750 Reflects Chairman retainer plus committee member fees; Board policy sets retainer schedule for directors and committee roles

Director cash retainer schedule (policy reference):

  • Board Chairman $85,000; non-chair member $50,000
  • Audit Chair $25,000; member $12,500
  • Compensation Chair $20,000; member $10,000
  • Nominating & Corporate Governance Chair $12,000; member $6,000
  • Research & Development Chair $15,000; member $7,500

Performance Compensation

ItemFiscal 2024Vesting / Structure
RSU grant-date fair value$200,010 Annual grant; generally vests by next annual meeting or 1-year anniversary
Option grant-date fair value$199,374 Annual grant; strike at grant-date FMV; typical time-based vest
  • Annual director equity target value $400,000 split 50% options / 50% RSUs; new director initial equity $600,000 split 50/50 .
  • No performance-conditioned director equity; awards are time-based (no dividends on unvested, no repricing; director comp capped at $900k, $1.5M in first year or if serving as Chairman/Lead Director) .

Other Directorships & Interlocks

CategoryDetails
Current public boardsStructure Therapeutics, Inc. (Chairman); Prothena Corporation plc (Chairman)
Past public boardsNuvation Bio (Chairman through Sep 2024); Intercept Pharmaceuticals, Inc.; Seagen Inc.
Internal network overlapUltragenyx CCO Erik Harris previously held commercial roles at InterMune; Welch served as InterMune CEO/Chairman

Expertise & Qualifications

  • Strong operating executive with strategic expertise in global pharma markets; extensive board governance experience .
  • Education: B.S. (University of Miami); M.B.A. (University of North Carolina) .

Equity Ownership

MetricAmountNotes
Total beneficial ownership68,335 shares (<1%) Less than 1% of outstanding
Common shares owned21,605 Direct holdings
Options exercisable within 60 days46,730 Included in beneficial ownership
RSUs outstanding (12/31/2024)5,345 As of year-end policy disclosure
Options outstanding (12/31/2024)74,130 Total outstanding options
Ownership guidelines3x annual retainer for directors; all directors in compliance by 12/31/2024
Hedging/pledgingProhibited for directors

Governance Assessment

  • Board effectiveness: As independent Chairman with 100% attendance and active committee roles (Compensation; Nominating & Governance), Welch supports strong oversight and governance rigor. The company maintains robust governance practices including clawback, anti-hedging/pledging, ownership guidelines, and independent committees .
  • Compensation oversight signal: As a Compensation Committee member, Welch was part of investor engagement response after a 74% say‑on‑pay approval in 2024, increasing PSU weightings and adding an absolute TSR cap—positive alignment steps .
  • Conflicts/related parties: Company reports no related-person transactions since Jan 1, 2024; Audit Committee reviews related-party dealings per policy—low conflict risk indicators .
  • Overboarding/time commitment: While chairing two external public boards, Welch remains within Ultragenyx’s overboarding limits (≤5 boards for non-CEO directors). Investors may monitor aggregate leadership commitments, but policy compliance and full attendance mitigate concerns .
  • RED FLAGS: None disclosed regarding pledging, hedging, repricing of director equity, tax gross-ups, or related-party transactions; director compensation subject to annual cap and no repricing permitted under plan .