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Jon Wigginton

Director at SUTRO BIOPHARMASUTRO BIOPHARMA
Board

About Jon Wigginton

Jon Wigginton, M.D., age 63, is an independent director of Sutro Biopharma and has served on the Board since November 2020. He is a physician-scientist with 25+ years in clinical oncology and immuno‑oncology drug development, currently serving as President, Research & Development at Bright Peak Therapeutics. Dr. Wigginton holds an M.D. and a B.S. in Biology from the University of Michigan. Sutro’s Board has affirmatively determined he is independent under Nasdaq and SEC rules.

Past Roles

OrganizationRoleTenureCommittees/Impact
MacroGenics, Inc.SVP, Clinical Development & Chief Medical OfficerAug 2013 – Mar 2020Led clinical strategy for antibody therapeutics in oncology
Bristol‑Myers (BMS)Therapeutic Area Head, Immuno‑Oncology, Early Clinical Research; Executive Director, Discovery Medicine‑Clinical Oncology2008 – 2013Early clinical development leadership in I/O
Merck Research LaboratoriesDirector of Clinical Oncology2006 – 2008Clinical oncology leadership
National Cancer Institute (NCI), CCRHead, Investigational Biologics Section, Pediatric Oncology Branch (and other roles)Prior to 2006Academic research/clinical leadership
MPM CapitalAdvisor2020 – 2021Investment/advisory role in healthcare

External Roles

OrganizationRoleTenureNotes
Bright Peak TherapeuticsPresident, Research & DevelopmentCurrentExecutive operator role in oncology R&D
Cullinan OncologySenior Advisor and Chairman of the SAB; previously CMOMost recent; prior CMO (dates not specified)Advisory and prior operating role
Checkmate PharmaceuticalsDirectorJan 2022 – May 2022Company acquired by Regeneron in May 2022
Society for Immunotherapy of Cancer (SITC)President and Board member (non‑profit)PriorProfessional society leadership

Board Governance

  • Committee assignments and chair roles
    • Science & Technology Committee: Chair. Responsibilities include oversight of R&D/platform strategy and IP strategy.
    • Compensation Committee: Member. Responsibilities include executive/director pay, incentive plan oversight, and succession planning (other than CEO).
  • Independence: Board determined Dr. Wigginton is independent under Nasdaq/SEC rules.
  • Attendance and engagement: In 2024, the Board met 7 times; Compensation Committee 6; Science & Technology Committee 5. No director attended fewer than 75% of aggregate Board and committee meetings. All directors attended the 2024 annual meeting.
  • Board leadership: CEO and Chair roles are separated (CEO: Jane Chung; Chair: Connie Matsui).

Fixed Compensation

Item (Non‑Employee Director Program)AmountNotes
Annual cash retainer$40,000Standard director retainer
Committee Chair retainersAudit: $20,000; Comp: $17,000; N&G: $10,000; S&T: $10,000Comp Chair increased from $14,000 in 2023; member fees below also increased
Committee member retainersAudit: $10,000; Comp: $8,500; N&G: $5,000; S&T: $5,000Comp member up from $7,000 in 2023
2024 fees earned (Wigginton)$57,750Reported cash fees in 2024

Performance Compensation

Equity ComponentStructure2024 Reported (Wigginton)
Annual option grant35,000 options; vest monthly until the earlier of next annual meeting or 1‑year anniversaryOption grant date fair value: $98,350
Initial option grant on joining Board35,000 options; vest monthly over 3 years; plus pro‑rated annual grant to next meetingProgram terms (not 2024 event)
Outstanding options (12/31/2024)N/A (aggregate count)121,000 options outstanding
  • Director equity is time‑based (no performance metrics); equity awards are options and vest as described above.

Other Directorships & Interlocks

CategoryDetails
Current public company boardsNone disclosed besides Sutro
Prior public company boardsCheckmate Pharmaceuticals (Jan–May 2022)
Compensation Committee interlocksNone; no Sutro executive served on the board/comp committee of another entity with reciprocal relationships in 2024

Expertise & Qualifications

  • Clinical oncology and immunotherapy drug development leader; experience contributed to strategies that led to FDA approvals of new treatments.
  • Executive and advisory roles across biotech and pharma (Bright Peak, Cullinan, MacroGenics, BMS, Merck; NCI academic leadership).
  • Education: M.D. and B.S. (Biology), University of Michigan.

Equity Ownership

Measure (as of 3/31/2025 unless noted)AmountNotes
Beneficial ownership (shares)118,083Represents options exercisable within 60 days; <1% of shares outstanding
Common shares held0No directly held common shares disclosed
Options exercisable within 60 days118,083Counted in beneficial ownership presentation
Total outstanding director options (12/31/2024)121,000Outstanding options as of year‑end 2024
Pledged or hedged sharesNone disclosed; company policy prohibits hedging and pledging by directorsPolicy prohibition on hedging/pledging

Governance Assessment

  • Strengths and alignment signals
    • Independent director; chairs the Science & Technology Committee and serves on the Compensation Committee, bringing deep immuno‑oncology and clinical development expertise to both oversight domains.
    • Strong meeting engagement: no directors fell below 75% attendance; Board/committee cadence suggests active oversight; all directors attended the 2024 annual meeting.
    • Director pay structure emphasizes equity via options with time‑based vesting (alignment), while cash retainers are modest; 2024 program modestly increased Comp Committee stipends and annual option size, consistent with market updates.
    • No related‑party transactions involving directors or 5% holders since Jan 1, 2023; Audit Committee maintains a formal related‑person transactions policy.
    • Broader governance practices include separated Chair/CEO roles, anti‑hedging/pledging policy, a clawback policy, and high 2024 Say‑on‑Pay support (98.8%)—a positive signal for investor confidence.
  • Potential watch items
    • Industry interlocks: While none rise to related‑party status, Dr. Wigginton’s concurrent executive role at Bright Peak and extensive network across oncology could present perceived conflicts in certain partnering contexts; however, Sutro discloses no related‑party transactions and affirms his independence.

Overall, Dr. Wigginton presents as a technically strong, independent director with high engagement and alignment through equity-heavy compensation and no identified conflicts, appropriate for Sutro’s R&D‑intensive strategy.