Cynthia Smith
About Cynthia Smith
Cynthia Smith (age 56) has served as an independent director of Protara Therapeutics (TARA) since January 2021. She is a biotechnology commercial executive with 20+ years of pharmaceutical industry experience, including senior roles at ZS Pharma (Chief Commercial Officer), Affymax (VP Market Access & Commercial Development), and Merck (Executive Director, Healthcare System & Medicare Strategy; crisis management for the Vioxx recall). She previously served in the White House Office of Management and Budget. Smith holds a BA (UNC Chapel Hill), an MS in public policy (Eagleton Institute, Rutgers), and an MBA (Wharton, UPenn) .
Past Roles
| Organization | Role | Tenure | Committees/Impact |
|---|---|---|---|
| ZS Pharma, Inc. | Chief Commercial Officer | Jun 2013 – Dec 2016 | Led through IPO and acquisition by AstraZeneca |
| Affymax, Inc. | VP, Market Access & Commercial Development | Oct 2008 – Mar 2013 | Commercial leadership in renal therapies |
| Merck & Co., Inc. | Executive Director, Healthcare System & Medicare Strategy; prior leadership roles | Jun 2000 – Oct 2008 | Corporate strategy, public policy, external affairs; global crisis management for Vioxx recall |
| White House OMB | Staff (Clinton Administration) | Not disclosed | Federal policy experience |
External Roles
| Organization | Role | Public/Private | Start/End |
|---|---|---|---|
| Agios Pharmaceuticals, Inc. | Director | Public | Since Aug 2022 |
| Spero Therapeutics, Inc. | Director | Public | Not disclosed |
| Akebia Therapeutics, Inc. | Director | Public | Not disclosed |
| Tvardi Therapeutics, Inc. | Director | Private | Not disclosed |
| Dicerna Pharmaceuticals, Inc. | Director (former) | Public (acquired by Novo Nordisk) | Served until Dec 2021 acquisition |
| French American Foundation | Board member | Non-profit | Not disclosed |
Board Governance
- Independence: The Board affirmatively determined Smith is independent under Nasdaq rules; eight of nine directors (including Smith) are independent .
- Board structure: Independent Chair (Luke Beshar); separation of chair and CEO roles to reinforce independent oversight .
- Committee assignments (FY2024): Chair, Compensation Committee; not a member of Audit, Nominating & Corporate Governance, or Scientific Advisory committees .
- Committee composition: Compensation Committee members are Barry Flannelly, Richard Levy, and Cynthia Smith (Chair); all are independent under Nasdaq Rule 5605(d)(2). Dr. Garceau served through the 2024→2025 compensation cycle and was then replaced by Dr. Levy .
- Meetings/attendance (FY2024): Board met 7x; Compensation Committee 6x. Each director attended at least 75% of the aggregate meetings of the Board and their committees. Independent directors held 5 executive sessions in 2024 .
- Nom/Gov process: Annual board/committee self-assessment (administered by counsel); independence and attendance considered in renomination decisions .
Attendance Snapshot (FY2024)
| Body | Meetings Held | Smith Attendance |
|---|---|---|
| Board of Directors | 7 | ≥75% of combined Board+committee meetings |
| Compensation Committee | 6 | ≥75% of combined Board+committee meetings |
Fixed Compensation
- 2024 Non-Employee Director Compensation (actual):
- Cash fees: $52,000
- Equity grant-date fair value (options): $20,598
- Total: $72,598
- No stock awards (RSUs) in 2024 .
| 2024 Director Compensation | Amount (USD) |
|---|---|
| Fees Earned or Paid in Cash | $52,000 |
| Option Awards (grant-date fair value) | $20,598 |
| Stock Awards (RSUs) | — |
| Total | $72,598 |
- Policy (effective April 1, 2025, cash elements): Annual cash retainer $40,000; additional committee member retainers: Audit $7,500, Compensation $6,000, Nominating & Corporate Governance $5,000, Scientific Advisory $25,000; chair retainers in lieu of member retainer: Audit Chair $15,000, Compensation Chair $12,000, Nominating Chair $9,000, Scientific Advisory Chair $50,000. Annual director compensation capped at $750,000 (or $1,000,000 in the first year of board service) based on accounting grant-date values .
Performance Compensation
- Equity framework for non-employee directors (service-based; no disclosed performance metrics):
- Initial option grant: 48,000 shares, vests 1/3 at 1-year anniversary then monthly over next 24 months.
- Annual option grant: 24,000 shares, vests in full on the first anniversary of the grant date.
- Change in control: All unvested director equity vests upon a “change in control” (single-trigger) .
- 2024 equity awarded to Smith: Options with grant-date fair value of $20,598; no RSUs granted .
No performance metrics or targets are disclosed for director compensation; director equity vests based on continued service rather than performance outcomes .
Other Directorships & Interlocks
| Company | Sector | Potential Interlock/Conflict with TARA |
|---|---|---|
| Agios (public) | Biopharma | None disclosed by TARA |
| Spero (public) | Biopharma | None disclosed by TARA |
| Akebia (public) | Biopharma | None disclosed by TARA |
| Tvardi (private) | Biopharma | None disclosed by TARA |
| Dicerna (public; acquired) | Biopharma | None disclosed by TARA |
- Related-party and conflicts: The proxy discloses a Related Person Transaction Policy and enumerates transactions since Jan 1, 2024. No related-party transactions involving Smith are disclosed (transactions listed are executive employment/separation and standard director/officer indemnification agreements) .
Expertise & Qualifications
- Commercial leadership across IPO/M&A contexts (ZS Pharma IPO and acquisition), market access, Medicare strategy, and crisis management (Vioxx) .
- Policy and governance experience (OMB; multiple public company boards) .
- Education: BA (UNC), MS Public Policy (Rutgers/Eagleton), MBA (Wharton) .
- Board determined independent; committee chair experience (Compensation) .
Equity Ownership
- Beneficial ownership (as of April 16, 2025): 61,750 shares beneficially owned via stock options exercisable within 60 days; percent of class: less than 1% .
- RSUs: None vested-but-unsettled or unvested at 12/31/2024 for Smith (0) .
- Outstanding director options (12/31/2024): 61,750 options for Smith .
| Ownership Detail | Amount |
|---|---|
| Beneficially Owned Shares (incl. options exercisable within 60 days) | 61,750; <1% of outstanding |
| RSUs vested but unsettled (as of 12/31/2024) | 0 |
| Options outstanding (as of 12/31/2024) | 61,750 |
- Hedging/pledging: Company policy prohibits short sales, options, hedging, and pledging/margining of company stock by directors; supports alignment with shareholders .
Governance Assessment
-
Strengths
- Independence affirmed; board majority independent and independent chair enhances oversight .
- Active role as Compensation Committee Chair; committee uses an independent compensation consultant and meets regularly in executive session; CEO excluded from decisions on his pay .
- Attendance: At least 75% of combined Board/committee meetings; independent directors held 5 executive sessions, indicating robust independent oversight .
- Clear related-party review policy; no Smith-related transactions disclosed .
- Anti-hedging and anti-pledging policy reduces misalignment risk .
-
Watch items / potential investor considerations
- Say-on-pay support was 72% in 2024, below many large-cap norms; the company reports outreach and added disclosure on performance goals—relevant given Smith’s role as Compensation Committee Chair .
- Director equity accelerates upon a change in control (single-trigger), which some investors scrutinize; however, this is common for director awards and limited to service-based equity .
- Multiple external board commitments (Agios, Spero, Akebia, Tvardi) increase time demands; the Nom/Gov committee reviews attendance and engagement during annual assessments and cited ≥75% attendance for all directors in 2024 .
-
Compensation mix context (2024): Approximately 72% cash ($52k) and 28% equity (options fair value $20.6k) for Smith, indicating meaningful but modest equity alignment versus cash retainers. Based on amounts in the 2024 non-employee director compensation table .
Committee Summary (FY2024)
| Committee | Role | Independence & Process |
|---|---|---|
| Compensation | Chair (Smith); members: Flannelly, Levy | All members independent; charter authorizes independent advisors; regular executive sessions; CEO excluded from own pay deliberations |
| Audit | Not a member | Audit chaired by Sargen; all members independent; financial expert designated (Sargen) |
| Nominating & Corporate Governance | Not a member | Oversees board refreshment, independence, annual self-assessments |
| Scientific Advisory | Not a member | Reviews R&D program risks |
Director Fee Policy (Effective April 1, 2025)
| Component | Amount |
|---|---|
| Annual cash retainer (all directors) | $40,000 |
| Chair, Board (additional) | $115,000 |
| Committee member retainers | Audit $7,500; Compensation $6,000; Nominating $5,000; Scientific Advisory $25,000 |
| Committee chair retainers (in lieu of member retainer) | Audit $15,000; Compensation $12,000; Nominating $9,000; Scientific Advisory $50,000 |
| Initial option grant (new directors) | 48,000; vests 1/3 at 1 year, then monthly over 24 months |
| Annual option grant | 24,000; vests in full at 1 year |
| Change in control | Single-trigger full vesting of unvested director equity |
| Annual cap | ≤$750,000 (≤$1,000,000 in first year) based on grant-date accounting value |