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Lesley Ann Calhoun

Director at Tango Therapeutics
Board

About Lesley Ann Calhoun

Lesley Ann Calhoun (age 59) has served as an independent director of Tango Therapeutics since March 2021 and is nominated to continue as a Class I director through the 2028 annual meeting. She is Executive Vice President, Chief Financial Officer (since June 2020) and Chief Operating Officer (appointed January 2025) at Aligos Therapeutics; previously she held senior finance roles at Global Blood Therapeutics, Hyperion Therapeutics, Theravance, and began her career in Deloitte’s audit practice. She holds a B.S. in Business Administration (Accounting) from San Francisco State University and is a Certified Public Accountant (inactive).

Past Roles

OrganizationRoleTenureCommittees/Impact
Aligos Therapeutics (NASDAQ: ALGS)EVP & CFO; COOCFO: Jun 2020–present; COO: Jan 2025–presentSenior finance and operations leadership in clinical-stage biotech
Global Blood Therapeutics (NASDAQ: GBT)SVP Finance & Administration; Chief Accounting OfficerAug 2016–Jun 2020Public company finance leadership
Hyperion TherapeuticsVP FinanceJan 2013–Sep 2015Prepared organization for acquisition by Horizon Pharma
Theravance (NASDAQ: TBPH)Sr Director Finance & Corporate ControllerAug 2005–Jan 2013Corporate controller, public company reporting
Deloitte & Touche LLPAudit practice1989–2001Audit experience; foundation for “financial expert” credentials

External Roles

OrganizationRoleTenureNotes
Aligos Therapeutics (NASDAQ: ALGS)EVP & CFO; COOCFO: Jun 2020–present; COO: Jan 2025–presentOperating executive role; no public board directorship disclosed

Board Governance

  • Committees:
    • Audit Committee Chair; designated “audit committee financial expert.” Audit committee members: Calhoun, Pothula, Borisy; 4 meetings in 2024.
    • Nominating & Corporate Governance Committee Member (Chair: Mace Rothenberg); 2 meetings in 2024.
  • Independence: Board determined all directors except the CEO are independent under Nasdaq/SEC rules.
  • Attendance: Board held 4 meetings in 2024; all directors attended at least 75% of board and committee meetings; 5 directors attended the 2024 annual meeting.
  • Election outcome (signal of investor confidence): Re-elected June 5, 2025 with 73,142,486 FOR; 10,476,404 WITHHELD; 13,226,662 broker non-votes.

Fixed Compensation

ComponentPolicy Amount (2024)Actual Earned 2024 ($)
Annual Director Cash Retainer$40,000 Included in total below
Audit Committee Chair$15,000 Included in total below
Nominating & Governance Committee Member$5,000 Included in total below
Total Cash FeesN/A59,750

Notes:

  • Committee fee revisions (May 2024): Comp Chair $12,000 (from $10,000); Comp Member $6,000 (from $5,000); Nom/Gov Chair $10,000 (from $8,000); Nom/Gov Member $5,000 (from $4,000).

Performance Compensation

Grant TypeAnnual Grant (2024 Policy)Grant Date & Units (2024)Grant Date Fair Value (2024)Vesting
Stock Options37,500 options per annual grant Annual grant; reflected in 2024 totals$194,588 12 equal monthly installments over 1 year
RSUs6,250 RSUs per annual grant Annual grant; reflected in 2024 totals$46,313 Vests fully on earlier of 1-year anniversary or next annual meeting
  • Change-in-control provision (non-employee directors): All unvested options and RSUs vest in full upon a change in control. Potential governance risk indicator.
  • No performance-based (PSU) metrics disclosed for director equity; awards are time-based.

Other Directorships & Interlocks

CategoryDetails
Current public company boardsNone disclosed for Calhoun.
External affiliations relevant to TNGXOperating executive at Aligos Therapeutics (biopharma). No related-party transactions with Aligos disclosed.
Related-party transactions oversightAudit committee reviews related-party transactions; Calhoun chairs audit committee (oversight responsibility).

Expertise & Qualifications

  • Audit committee financial expert designation; extensive public company finance and accounting leadership.
  • Deep biotech sector experience across multiple companies and stages.
  • CPA (inactive); formal accounting education (San Francisco State University, B.S.).
  • Governance roles include audit oversight, risk management coordination, and nominating/governance responsibilities.

Equity Ownership

MetricAs of DateAmountNotes
Beneficial ownership (total)Apr 1, 2025189,300 sharesEntirely options exercisable within 60 days; <1% ownership.
Outstanding options (board-level)Dec 31, 2024192,425Options held as director.
Outstanding RSUs (board-level)Dec 31, 20246,250RSUs held as director.
Form 4 grants (annual)Jun 5, 202537,500 options; 6,250 RSUsReported as awards; post-transaction holdings show 37,500 (options) and 12,500 (common).

Insider Trades (Form 4 snapshot)

Filing DateTransaction DateTypeSecurityQuantityPricePost-Transaction Holdings
2025-06-092025-06-05AwardStock Option (Right to Buy)37,500$3.5137,500
2025-06-092025-06-05AwardCommon Stock (RSUs)6,250$0.0012,500

Governance Assessment

  • Strengths: Independent director; audit chair and “financial expert” designation; strong re-election mandate; consistent meeting participation; director equity awards balanced with cash retainers, aligning with shareholder interests.
  • Pay structure changes: 2024 policy increased annual director equity grants (options to 37,500; RSUs to 6,250) and raised committee fees to align with peer median—signals competitive compensation but increases equity dilution risk modestly.
  • Risk indicators:
    • Single-trigger vesting of all unvested director equity upon change in control (potential misalignment if transaction benefits are not directly tied to long-term performance).
    • No Calhoun-specific related-party transactions disclosed; broader related-party arrangements (Sesame, RevMed) were reviewed and approved by non-interested directors, with audit committee oversight—mitigates conflict risk.
  • Shareholder sentiment: 2025 Say-on-Pay approved (63.5M FOR; 20.1M AGAINST; 34k ABSTAIN; annual frequency selected by stockholders), indicating acceptable alignment of compensation programs with investor expectations.

Director Compensation (2024 summary for Calhoun)

Component2024 Amount ($)
Fees Earned or Paid in Cash59,750
Stock Awards (RSUs) – grant date fair value46,313
Option Awards – grant date fair value194,588
Total300,651
Aggregate holdings at 12/31/2024192,425 options; 6,250 RSUs

Additional Governance Details

  • Policy on trading/derivatives: Company prohibits short sales and derivative transactions by directors and insiders (enhances alignment and compliance).
  • Indemnification agreements: Standard indemnity for directors and officers under Delaware law.

RED FLAGS

  • Single-trigger acceleration of unvested director equity upon change in control.