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Melissa Starovasnik

Director at Twist BioscienceTwist Bioscience
Board

About Melissa A. Starovasnik, Ph.D.

Independent director of Twist Bioscience since August 2021; age 59. Former Senior Scientific Advisor, Research at Genentech (2017–2021) and long-time research leader focused on protein and antibody drug discovery; B.S. in Chemistry and Ph.D. in Biochemistry from University of Washington. Currently serves as Compensation Committee Chair at TWST, with expertise in biotechnology R&D leadership, risk oversight, and talent management .

Past Roles

OrganizationRoleTenureCommittees/Impact
Genentech, Inc.Senior Scientific Advisor, Research2017–2021Scientific leadership in protein/antibody discovery
Genentech, Inc.VP, Protein Sciences; Head of Large Molecule Drug Discovery2011–2017Led ~200 employees; drug discovery portfolio oversight
Genentech, Inc.Various roles of increasing responsibility1993–2017Integral member of research leadership team

External Roles

OrganizationRoleTenureNotes
Aarvik Therapeutics Inc.Scientific Advisory Board MemberCurrentAdvisory role (non-director)
AbiologicsScientific Advisory Board MemberCurrentAdvisory role (non-director)
AdaxionScientific Advisory Board MemberCurrentAdvisory role (non-director)
Denali Therapeutics Inc.Scientific Advisory Board MemberCurrentDNLI is public; role is SAB, not board director
Expansion TherapeuticsScientific Advisory Board MemberCurrentAdvisory role (non-director)
Medium BiosciencesScientific Advisory Board MemberCurrentAdvisory role (non-director)

Board Governance

  • Committee assignments: Compensation Committee (Chair); committee comprised of Chess, Crandell, Ragusa, and Starovasnik; all independent under Nasdaq/SEC, with Ragusa recusing himself from approving equity grants to directors/officers for Rule 16b-3 purposes .
  • Independence: Board determined Starovasnik is independent under SEC and Nasdaq standards .
  • Attendance: During FY2024, each director attended at least 75% of Board/committee meetings; Board held 4 meetings; Audit & Risk held 5; Compensation held 4; Nominating & Corporate Governance held 4; all then-serving directors attended the 2024 Annual Meeting .
  • Leadership: CEO serves as Chair; Robert Chess is Lead Independent Director, enabling regular executive sessions for independent oversight .

Fixed Compensation

ComponentAmount/TermsNotes
Board annual cash retainer (Member)$45,000 Paid quarterly in arrears
Compensation Committee Member retainer$7,500 Higher retainer for chair
Compensation Committee Chair retainer$17,500 Chair premium
Audit Committee Member retainer$10,000 If applicable
Nominating & Corporate Governance Member retainer$5,000 If applicable
Corporate Responsibility Lead Director retainer$10,000 (Lead Director role, not applicable to Starovasnik) Reference schedule

Director cash paid (FY2024):

NameFees Earned or Paid in Cash ($)
Melissa A. Starovasnik, Ph.D.$62,500

Performance Compensation

Grant TypeGrant DateShares/UnitsGrant Date Fair Value ($)VestingNotes
Annual RSU grantFeb 6, 20245,815 RSUs$214,981 100% vest on earlier of 1-year anniversary or next annual meeting, subject to service Non-employee director annual grant under policy
Stock options (FY2024 awards)No options granted to directors in FY2024
Options outstanding (as of 9/30/2024)2,739Exercisable position disclosure onlyAggregate options held by Starovasnik
  • Director equity grant policy: Initial director RSU grant value $395,000 over 3 years (time-based); annual RSU grant target $240,000, vests on earlier of one year or next annual meeting; change-in-control acceleration for director RSUs immediately prior to closing if the director remains a service provider until such time .
  • Clawback: Compensation Recovery Policy approved Nov 2, 2023 for executive performance-based incentives; directors’ RSUs are time-based; policy applies to covered executive officers .
  • Hedging/pledging: Company prohibits hedging and pledging of company securities; limited exceptions may be granted; margin accounts not permitted .

Other Directorships & Interlocks

CategoryDetails
Public company directorships (current)None disclosed for Starovasnik .
Advisory roles (potential ecosystem interlocks)SAB memberships at multiple biotech firms (e.g., Denali Therapeutics), which may indicate industry connectivity but are not board directorships .
Board-level related-party transactions (context)TWST reported revenue from GeneDx ($8M FY2024; CEO Leproust sits on GeneDx board) and GRAIL ($3M FY2024; director Ragusa is GRAIL CEO); relationships operated on standard commercial terms and reviewed under related-party policy; Ragusa recuses from certain comp matters under Rule 16b-3 .

Expertise & Qualifications

  • Deep biotechnology R&D expertise, including protein sciences and large molecule discovery leadership; risk oversight, strategic planning, technology innovation, and talent management highlighted among Board skills matrices .

Equity Ownership

HolderCommon StockOptions Exercisable within 60 daysRSUs Vesting within 60 daysAggregate Beneficial Ownership% of Outstanding
Melissa A. Starovasnik, Ph.D.11,339 2,739 14,078 <1%
  • Section 16(a) compliance: Seven Form 4s (including Starovasnik) were filed one day late related to the 2024 annual director equity awards—minor administrative lapse disclosed .
  • Ownership guidelines: Company discloses executive stock ownership guidelines (CEO 3x salary; other NEOs 1x) and retention requirements; director-specific ownership guidelines not disclosed .

Governance Assessment

  • Committee leadership and independence: As Compensation Committee Chair, Starovasnik oversees executive pay design with an independent consultant (Meridian), annual risk assessments, double-trigger CIC provisions, and prohibited hedging/pledging—aligned with governance best practices and investor expectations .
  • Attendance and engagement: Board and committees met regularly in FY2024; directors met the 75% attendance threshold and all attended the 2024 Annual Meeting, supporting effective oversight and engagement .
  • Director compensation mix: For FY2024, Starovasnik’s compensation was primarily equity via time-based RSUs ($214,981) with modest cash fees ($62,500)—typical for non-employee directors and supportive of shareholder alignment; no director stock options granted in FY2024 .
  • Potential conflicts and mitigating controls: While TWST has commercial relationships with GeneDx and GRAIL tied to other directors/executives, the Audit & Risk Committee reviews related-party transactions under a formal policy, terms are standard, and Ragusa’s recusal mitigates Rule 16b-3 conflicts within the Compensation Committee .
  • Say-on-Pay signal: 2024 Say-on-Pay passed with approximately 94% support, indicating broad investor approval of compensation practices overseen by the committee chaired by Starovasnik ; formal vote totals recorded in the 8-K confirm strong support (For: 43,215,571; Against: 2,904,714; Abstentions: 31,874; Broker Non-Votes: 6,148,005) .

Supplemental Quantitative Disclosures

Director Compensation (FY2024)

NameFees Earned or Paid in Cash ($)Stock Awards ($)Option Awards ($)Total ($)
Melissa A. Starovasnik, Ph.D.62,500 214,981 277,481

Annual Director Equity Grant Terms

ItemValue
Annual RSU grant shares5,815 RSUs
Grant dateFeb 6, 2024
Vesting100% on earlier of one year or next annual meeting, subject to service
Grant date fair value$214,981

Board & Committee Meetings (FY2024)

BodyMeetings Held
Board of Directors4
Audit & Risk Committee5
Compensation Committee4
Nominating & Corporate Governance Committee4

Say-on-Pay Voting (2024 Annual Meeting)

Votes ForVotes AgainstAbstentionsBroker Non-Votes
43,215,571 2,904,714 31,874 6,148,005

RED FLAGS and notes:

  • Minor Section 16(a) administrative lapse (one-day late Form 4) related to annual director grants—immaterial but disclosed .
  • Board-related party relationships with GeneDx and GRAIL warrant continued monitoring; current mitigants include standard commercial terms, formal related-party review, independence determinations, and Ragusa’s recusal from certain equity approvals .
  • Directors’ equity is time-based RSUs (no performance metrics), typical for governance alignment but not tied to explicit performance outcomes; executive PRSUs (not director) remain performance-based, supporting overall pay-for-performance philosophy .