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Katherine Stueland

Katherine Stueland

Chief Executive Officer at GeneDx Holdings
CEO
Executive
Board

About Katherine Stueland

Katherine Stueland is Chief Executive Officer and a Class II director of GeneDx Holdings Corp. (Nasdaq: WGS), serving since April 2022; she is 49 and holds a B.S. in English language and literature from Miami University of Ohio . Under her leadership, Q4 2024 revenues reached $95.3M with adjusted gross margin of 70% and adjusted net income of $16.8M, while exome/genome revenues grew 101% year-over-year; 2025 revenue guidance is $350–$360M with at least 30% exome/genome volume growth . The Board separates the roles of Chair and CEO (Jason Ryan as Chair), supporting oversight and mitigating dual-role concerns; Ms. Stueland is not independent due to her executive role .

Past Roles

OrganizationRoleYearsStrategic Impact
GeneDx, LLC (Legacy GeneDx)President & CEOPre-April 2022Led operations pre-acquisition by GeneDx Holdings
Invitae CorporationChief Commercial Officer2016–2021Commercial leadership in genetic testing
Invitae CorporationHead of Communications & Investor Relations2013–2016Helped Invitae transition from private to public company
Vivo CommunicationsPrincipal2013Corporate communications leadership
Dendreon CorporationVP, Communications & Investor Relations2009–2012Investor relations in biotech

External Roles

OrganizationRoleYearsStrategic Impact
Rivkin Center (non-profit)Board member (prior)Not disclosedWomen’s cancer treatment/prevention advocacy

Board Governance

  • Board leadership structure separates CEO and Chair; Jason Ryan serves as non-executive Chair, and Ms. Stueland is CEO .
  • Independence: all directors except Ms. Stueland and Mr. Ryan are independent; committee membership is fully independent .
  • Committee roles: Ms. Stueland does not serve on Audit, Compensation, or Nominating & Governance committees; committee composition is shown below :
    • Audit: Meister (Chair), Leproust, Pfenniger
    • Compensation: Ruch (Chair), Casdin, Leproust
    • Nominating & Governance: Leproust (Chair), Ruch, Casdin
  • Stock ownership guidelines (adopted April 10, 2025): CEO 300% of base salary, other executives 100%, non-employee directors 300% of cash retainer; unvested time-based RSUs count, options and performance-based awards do not; compliance expected within 5 years .

Fixed Compensation

Metric20232024
Base Salary$675,000 $675,000
Target Bonus (% of Salary)100% (per employment agreement) 100% (per employment agreement)
Actual Bonus Paid$950,000 (annual bonus $675,000 + supplemental $275,000)
Director Compensation (as a director)$0 $0

Performance Compensation

Incentive TypeMetric(s)WeightingTargetActual/PayoutVesting/Timing
Annual Cash Bonus (2024)Corporate objectives: revenue growth, gross margins, efficient cash usage; individual goals Not disclosed CEO: 100% of salary $675,000 annual bonus + $275,000 supplemental payout Paid post year-end per program
RSUs (Time-based)Service-based only N/AN/AGrant-date fair value $2,796,800 (2024) Quarterly or annual installments; generally 4-year schedules
Performance RSUs (introduced March 2025)Revenue and adjusted net income Not disclosed Not disclosed Not disclosedTerms introduced in 2025; vesting per award agreements

Equity Ownership & Alignment

Beneficial Ownership (as of April 15, 2025)Shares% Outstanding
Total beneficial ownership (CEO)92,848 (1,720 shares owned; 80,707 options exercisable within 60 days; 10,421 RSUs vesting within 60 days) <1%
  • Outstanding equity awards (12/31/2024) for Ms. Stueland include unvested RSUs and options; vesting terms summarized below .
  • Insider trading policy prohibits hedging and short sales; pledging is prohibited unless approved by the ITP Officer and consistent with company policy .
  • Stock ownership guidelines: CEO must hold shares equal to 300% of base salary within five years; unvested time-based RSUs count; options and performance RSUs do not .
  • Section 16(a) compliance: Form 4 filings for RSU grants were filed 359 days late for Ms. Stueland (March 28, 2025), a governance caution .

Outstanding Equity Awards and Vesting Schedules (CEO as of 12/31/2024)

Grant DateInstrumentQuantityExercise PriceVesting ScheduleMarket Value (12/31/2024)
5/2/2022Stock Options (exercisable)67,255 $72.60 1/4 on 4/29/2023 and 4/29/2024; 1/16 quarterly to 4/29/2026 N/A
5/2/2022Stock Options (unexercisable)40,355 $72.60 As above N/A
5/2/2022RSUs (unvested)23,244 N/AQuarterly over 4 years $1,786,534
12/9/2022RSUs (unvested)52,372 N/AQuarterly over 4 years $4,025,312
4/26/2023RSUs (unvested)168,750 N/AQuarterly over 4 years $12,970,125
3/26/2024RSUs (unvested)320,000 N/AQuarterly installments each anniversary of grant $24,595,200

Note: Market values based on closing price $76.86 on 12/31/2024 .

Employment Terms

ProvisionCEO Term
EmploymentAt-will; base salary $675,000; target bonus 100% of salary
Severance (non-CIC)24 months base salary continuation; 12 months health coverage; release required
Severance (CIC window)24 months base salary; lump sum 2x target annual bonus; 24 months health; accelerated vesting of outstanding equity; release required; CIC window from 3 months before engagement with counterparty to 12 months post-CIC
ClawbackExecutive compensation recovery policy for restatements within prior 3 fiscal years
Hedging/PledgingHedging/short sales prohibited; pledging requires approval and policy compliance

Compensation Committee Analysis

  • Composition: Compensation Committee chaired by Joshua Ruch; members Eli Casdin and Emily Leproust; all independent and non-employees .
  • Consultant: Aon plc engaged as independent compensation consultant to advise on peer group construction, pay framework, incentive design, and risk assessment; Committee determined Aon’s independence and lack of conflicts .
  • CEO pay setting: CEO recuses herself from deliberations; Committee consults full Board on CEO goals and pay; CEO provides recommendations for other executives (Committee also relies on Aon analysis) .

Performance & Track Record

  • Q4 2024: Revenues $95.3M; adjusted gross margin 70%; adjusted net income $16.8M; exome/genome revenues +101% YoY, with 20,000 tests and improved reimbursement rates ($3,500 per test after denials) .
  • 2025 Outlook: Revenue $350–$360M; at least 30% exome/genome volume and revenue growth; maintain adjusted net income profitability each quarter and full year; adjusted gross margin guidance 65–67% .

Director Compensation (for context)

  • 2024 non-employee director cash retainer $40,000; additional $40,000 for Chair; annual RSU grant valued at $338,480; committee retainers as disclosed .
  • Updated policy (April 10, 2025): Cash retainer $50,000; annual RSU grant $240,000; new-director RSU $420,000 vesting over three years; total cap $750,000 annually ($1,000,000 in initial year) .
  • Ms. Stueland, as CEO-director, received no director compensation .

Investment Implications

  • Pay-for-performance alignment improving: Introduction of performance RSUs in 2025 tied to revenue and adjusted net income should strengthen incentive linkage; historically, equity was time-based RSUs with a substantial unvested overhang .
  • Retention vs. selling pressure: Large unvested RSU tranches (e.g., 320,000 granted in 2024) vest quarterly and could create periodic selling pressure upon settlement; beneficial ownership remains <1%, suggesting limited “skin in the game” despite options/RSUs .
  • Change-of-control economics: CEO’s CIC package (24 months base, 2x target bonus, full equity acceleration, 24 months health) indicates meaningful parachute cost that may affect M&A calculus; clawback policy and anti-hedging/pledging mitigate adverse alignment risks .
  • Governance: Separation of Chair/CEO and fully independent committees are positives; however, late Section 16 filings for RSUs present a minor red flag on compliance rigor; stock ownership guidelines adopted in 2025 should increase long-term alignment (CEO target 300% base) .