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Thomas Fuchs

Director at GeneDx Holdings
Board

About Thomas Fuchs

Thomas Fuchs, Dr.sc., is a Class I, non-employee director of GeneDx Holdings Corp. appointed effective September 17, 2025, with a term expiring at the 2028 Annual Meeting . He serves as SVP and Chief AI Officer at Eli Lilly, and previously led AI and computational pathology at Mount Sinai; he holds a PhD in machine learning from ETH Zurich and a master’s in technical mathematics from Graz University of Technology . The company disclosed it intends to compensate him under the Non-Employee Director Compensation Policy and to enter a standard indemnification agreement; no related-party transactions requiring Item 404(a) disclosure were identified .

Past Roles

OrganizationRoleTenureCommittees/Impact
Eli Lilly and CompanySVP & Chief AI OfficerNot disclosedLeads AI strategy across discovery, trials, manufacturing, commercial; scales AI/ML solutions
Icahn School of Medicine at Mount SinaiDean & inaugural Department Chair for AI and Human Health; Barbara T. Murphy ProfessorNot disclosedBuilt AI/computational pathology programs; directed Hasso Plattner Institute for Digital Health
Hasso Plattner Institute for Digital Health (Mount Sinai)DirectorNot disclosedLed digital health initiatives integrating data/AI
Memorial Sloan Kettering Cancer CenterResearch/leadership positionsNot disclosedApplied AI to diagnostic medicine
NASA JPL / CaltechResearch positionsNot disclosedAdvanced ML applications; technical leadership
Paige AI (company founder)FounderNot disclosedCommercialized computational pathology AI

External Roles

OrganizationRoleBoard/CommitteeNotes
Eli Lilly and CompanySVP & Chief AI OfficerNot a board roleExternal executive position; no WGS related-party transactions disclosed in connection with appointment

Board Governance

  • Independence: GeneDx states all directors other than the CEO and Chairman qualify as independent under Nasdaq rules; committee members are independent under Nasdaq standards . Fuchs is a non-employee director; the 8-K does not explicitly state the independence determination at appointment .
  • Committee assignments: As of the April 30, 2025 proxy, committees were comprised without Fuchs (pre-appointment). Audit: Meister (Chair), Leproust, Pfenniger; Compensation: Ruch (Chair), Casdin, Leproust; Nominating & Governance: Leproust (Chair), Ruch, Casdin . Fuchs’ committee assignments were not disclosed in the 8-K and were pending subsequent filings .
  • Attendance: In 2024, the Board met 6 times; Audit 4; Compensation 5; Nominating 4; each director attended at least 75% of meetings—note Fuchs was not yet a director in 2024 .
  • Executive sessions: Independent directors meet in executive session alongside regular Board meetings .

Fixed Compensation

ComponentAmountDetails
Annual cash retainer (non-employee director)$50,000Payable quarterly; increased from $40,000 in 2024
Audit Committee member retainer$10,000Chair receives $20,000 (in lieu of member retainer)
Compensation Committee member retainer$7,500Chair receives $15,000 (in lieu of member retainer)
Nominating & Governance Committee member retainer$5,000Chair receives $10,000 (in lieu of member retainer)
Non-executive Chairman additional retainer$50,000Additional to director retainer (applies to Chairman)
Annual director compensation cap$750,000Raised to $1,000,000 in initial calendar year of service

Performance Compensation

Equity TypeGrant ValueVestingPerformance Metrics
Initial RSU grant (new directors)$420,000Vests over three years, subject to continued service
Annual RSU grant (incumbent directors)$240,000Vests on earlier of first anniversary or next annual meeting, subject to service
OptionsNot part of current director policyN/AN/A
Metrics (directors)None disclosedTime-based RSUs onlyNo TSR/financial metrics tied to director RSUs

Other Directorships & Interlocks

CompanyRoleInterlock/ConflictNotes
None disclosedNo other public company directorships disclosed at appointment . Prior affiliations with Mount Sinai are historical; no Item 404(a) related-party transactions disclosed for Fuchs .

Expertise & Qualifications

  • AI/ML leadership across pharma R&D, clinical trials, manufacturing, and commercial operations; extensive background in computational pathology and digital health .
  • Founder of Paige AI, with prior roles at Memorial Sloan Kettering, NASA JPL, and Caltech, indicating deep technical credentials relevant to GeneDx’s AI-driven genomics strategy .
  • Education: PhD (ETH Zurich), master’s in technical mathematics (Graz University of Technology) .

Equity Ownership

Policy ElementRequirementNotes
Director stock ownership guideline300% of annual cash director retainerApplies to non-employee directors; includes unvested time-based RSUs, excludes options and unvested performance-based awards
Time to complyWithin 5 years of becoming a directorFor Fuchs, expected by September 2030 based on Sept 17, 2025 appointment
Counting shares toward guidelineDirect/beneficial ownership and unvested time-based RSUs count; options and performance-based RSUs do notClarified in Stock Ownership Guidelines

Insider Trades

DateFilingTransactionDetails
Sep 17–19, 2025Form 4Initial grant/appointment reportingAppointment as director and initial RSU grant consistent with policy; $420,000 RSUs vest over three years

Governance Assessment

  • Board effectiveness: Fuchs adds domain-leading AI and computational pathology expertise aligned to GeneDx’s strategy, likely enhancing oversight on data/AI initiatives and biopharma partnerships . Compensation and attendance structures appear robust; committees operate with independent members under Nasdaq standards .
  • Independence and conflicts: The company disclosed no related-party transactions for Fuchs upon appointment (Item 404(a)), and he is a non-employee director; monitor future interactions with Lilly for potential related-party considerations .
  • Incentive alignment: Director equity is time-based RSUs with clear vesting; ownership guidelines (300% of retainer within five years) strengthen alignment; caps limit excessive compensation .
  • RED FLAGS: None disclosed specific to Fuchs. Broader related-party exposures exist between GeneDx and Mount Sinai/OPKO with fair-market-value arrangements and disclosed subleases; these are systemic considerations rather than Fuchs-specific .