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Crestline Management, LP

CIK:0001536054
Hedge Fund
$20B AUM
3 holdings
Fort Worth, TX, United States
Founded:1997
218 employees
Latest filing:Jun 30, 2025

Crestline Management, L.P. is a Fort Worth, Texas-based financial management company founded in 1997. It serves institutional clients, high net worth individuals, and family offices with alternative investment management services. Crestline specializes in credit and opportunistic investments, offering a range of strategies across equity, fixed income, and alternatives. The firm manages a diversified family of investment products and is known for its disciplined, research-driven approach. Crestline has approximately 218 employees and manages a significant suite of funds for clients globally.

Investment Strategy

Crestline Management, L.P. focuses on alternative investments, with a core specialization in credit and opportunistic strategies. The firm provides creative capital solutions including senior-secured, unitranche, structured capital, and specialty finance, as well as niche real estate investments. Its philosophy emphasizes delivering risk-adjusted returns using disciplined research and a collaborative, partnership-oriented portfolio management culture. Crestline tailors solutions for emerging companies, financial sponsors, and investors seeking growth capital and bridge financing. The firm serves sophisticated institutions, family offices, and high-net-worth individuals globally, adapting to various market cycles with both liquid and illiquid solutions.

Latest 13F Filing Activity

Crestline Management, LP filed their most recent 13F report on Jun 30, 2025 disclosing 3 equity positions with a total 13F market value of $63B. The fund increased holdings in Sana Biotechnology Inc., 8x8 Inc. New, Denali Therapeutics Inc.. Crestline Management, LP reduced exposure to Denali Therapeutics Inc., 8x8 Inc. New, Sana Biotechnology Inc..

Top Buys
D
DNLIDENALI THERAPEUTICS INC
-$2.55B
S
SANASANA BIOTECHNOLOGY INC
+$1.92B
E
EGHT8X8 INC NEW
-$39.6M
Top Sells
D
DNLIDENALI THERAPEUTICS INC
-$2.55B
S
SANASANA BIOTECHNOLOGY INC
+$1.92B
E
EGHT8X8 INC NEW
-$39.6M

Top Holdings

D
DNLIDENALI THERAPEUTICS INC
+86.3%$54.01B
S
SANASANA BIOTECHNOLOGY INC
+10.6%$6.61B
E
EGHT8X8 INC NEW
+3.1%$1.94B

Equity Positions (3)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
DENALI THERAPEUTICS INC86.33%$54.01B3,860,732$41.05$13.99-$2.55B
SANA BIOTECHNOLOGY INC10.56%$6.61B2,420,937$18.45$2.73+$1.92B
8X8 INC NEW3.10%$1.94B990,580$4.32$1.96-$39.6M

Industry Allocation

BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+96.4%
SERVICES-COMPUTER PROCESSING & DATA PREPARATION
+3.6%