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Knoll Capital Management, LLC
Knoll Capital Management, LLC is an investment management firm headquartered in Miami, Florida, USA. The firm operates as an SEC-registered investment adviser and manages portfolios primarily focused on public equities, with an emphasis on healthcare, life sciences, and gold mining sectors. Founded by Fred Knoll, the firm manages client capital through separately managed accounts and pooled investment vehicles, serving high-net-worth individuals and institutions. As of 2025, the firm reports over $140 million in assets and maintains a lean team structure.
Investment Strategy
Knoll Capital Management, LLC specializes in fundamental research-based investing, primarily targeting undervalued or underfollowed companies in the healthcare, biotech, and natural resources sectors, with a tactical allocation to gold and precious metals. The firm’s strategy emphasizes deep sector knowledge, long-term value investing, and active portfolio management, seeking to identify companies with significant growth potential or catalysts that may unlock value. The portfolio includes both long and selectively opportunistic positions, reflecting a mix of conviction holding and tactical exposure.
Latest 13F Filing Activity
Knoll Capital Management, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 34 equity positions with a total 13F market value of $141M. The fund increased holdings in Skeena Res LTD Cad, Kinross Gold Corp., Sandstorm Gold LTD among other positions. Knoll Capital Management, LLC reduced exposure to Aldeyra Therapeutics Inc., Equinox Gold Corp., Ocular Therapeutix Inc. among others.
Top Holdings
Equity Positions (34)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
A ALDX | Aldeyra Therapeutics Inc | 14.91% | $21.0M | 5,475,516 | $5.57 | $3.83 | -$10.5M |
E ENTX | Entera Bio Ltd | 7.95% | $11.2M | 5,881,879 | $2.57 | $1.90 | +$1.2M |
G GLD | SPDR Gold Trust | 6.94% | $9.8M | 32,000 | $207.82 | $304.83 | +$534.1K |
M MGTX | MeiraGTX Holdings | 5.79% | $8.2M | 1,250,000 | $4.17 | $6.52 | -$325.0K |
K KGC | Kinross Gold Corp | 4.89% | $6.9M | 440,000 | $4.56 | $15.63 | +$1.3M |
Industry Allocation
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