Sign in

Octagon Capital Advisors LP

CIK:0001839435
Hedge Fund
$456M AUM
30 holdings
New York, NY, United States
Founded:2019
10 employees
Latest filing:Jun 30, 2025

Octagon Capital Advisors LP is an SEC-registered investment management firm headquartered in New York, NY. Incorporated in Delaware, the firm was founded in 2019 and operates as a hedge fund focused on managing institutional client assets in public equity markets, primarily within healthcare and biotechnology sectors. As of 2024, it manages over $450 million in AUM and employs a modest team to serve its clients.

Investment Strategy

Octagon Capital Advisors LP primarily utilizes a fundamental, research-driven approach focused on investment opportunities in the life sciences, biotechnology, and healthcare sectors. The firm's strategy involves deep scientific diligence, thematic investing, and active portfolio management, seeking to identify undervalued public companies with significant growth potential in therapeutics, diagnostics, and medical technologies.

Top Buys
V
VRNAVERONA PHARMA PLC
+$18.1M
S
SPRYARS PHARMACEUTICALS INC
+$15.7M
T
TSHATAYSHA GENE THERAPIES INC
+$14.2M
K
KYMRKYMERA THERAPEUTICS INC
+$11.6M
D
DBVTDBV TECHNOLOGIES S A
+$9.3M
Top Sells
N
NUVB-WTNUVATION BIO INC
-$47.8M
A
APLSAPELLIS PHARMACEUTICALS INC
-$30.2M
A
APGETAYSHA GENE THERAPIES INC
-$14.9M
H
HUMAVERONA PHARMA PLC
-$13.8M
S
SNDXSYNDAX PHARMACEUTICALS INC
-$11.1M

Top Holdings

D
DNTHDIANTHUS THERAPEUTICS INC
+9.6%$43.6M
A
AVBPARRIVENT BIOPHARMA INC
+9.3%$42.4M
V
VRNAVERONA PHARMA PLC
+7.0%$31.9M
T
TSHATAYSHA GENE THERAPIES INC
+6.4%$29.1M
S
SPRYARS PHARMACEUTICALS INC
+5.2%$23.6M

Equity Positions (28)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
D
DNTH
DIANTHUS THERAPEUTICS INC9.57%$43.6M2,341,667$23.31$18.63+$1.1M
A
AVBP
ARRIVENT BIOPHARMA INC9.30%$42.4M1,946,054$19.08$21.77+$4.3M
V
VRNA
VERONA PHARMA PLC7.00%$31.9M337,000$44.94$94.58+$18.1M
T
TSHA
TAYSHA GENE THERAPIES INC6.38%$29.1M12,592,500$2.14$2.31+$14.2M
S
SPRY
ARS PHARMACEUTICALS INC5.17%$23.6M1,350,000$15.20$17.45+$15.7M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+74.6%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+14.6%
MEDICINAL CHEMICALS & BOTANICAL PRODUCTS
+3.0%
BLANK CHECKS
+0.6%