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Stonepine Capital Management, LLC

CIK:0001440771
Hedge Fund
$103M AUM
59 holdings
Bend, OR, United States
Founded:2006
6 employees
Latest filing:Jun 30, 2025

Stonepine Capital Management, LLC is a US-based hedge fund manager headquartered in Bend, Oregon. Founded in 2006, the firm principally invests in equity and equity-related securities, with an employee count of approximately 6 professionals. Stonepine Capital Management primarily serves institutional investors and high-net-worth individuals, offering investment advisory services with a focus on value-driven public equities.

Investment Strategy

Stonepine Capital Management focuses on value-oriented investments in public equities, emphasizing long-term growth and capital appreciation. Their investment approach is centered on deep fundamental analysis to identify undervalued stocks, particularly in the small- and mid-cap sectors. The firm pursues positions that offer both potential upside and a margin of safety, with an opportunistic outlook across various sectors.

Top Buys
A
ADMAADMA BIOLOGICS INC
+$13.6M
A
ACADACADIA PHARMACEUTICALS INC
+$4.7M
I
ITOSITEOS THERAPEUTICS INC
+$2.4M
I
INDVINDIVIOR PLC
+$2.3M
A
ARDXARDELYX INC
+$2.2M
Top Sells
A
ANIPANI PHARMACEUTICALS INC
-$11.1M
O
OPTNOPTINOSE INC
-$7.2M
E
EOLSEVOLUS INC
-$5.2M
U
URGNUROGEN PHARMA LTD
-$3.7M
A
AQSTAQUESTIVE THERAPEUTICS INC
-$3.0M

Top Holdings

A
ADMAADMA BIOLOGICS INC
+13.4%$13.7M
E
EOLSEVOLUS INC
+8.3%$8.4M
Z
ZVRAZEVRA THERAPEUTICS INC
+6.7%$6.8M
V
VSTMVERASTEM INC
+5.5%$5.6M
I
INDVINDIVIOR PLC
+5.1%$5.2M

Equity Positions (55)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
A
ADMA
ADMA BIOLOGICS INC13.40%$13.7M750,000$2.47$18.21+$13.6M
E
EOLS
EVOLUS INC8.28%$8.4M916,500$7.64$9.21-$5.2M
Z
ZVRA
ZEVRA THERAPEUTICS INC6.70%$6.8M775,620$7.28$8.81+$2.0M
V
VSTM
VERASTEM INC5.54%$5.6M1,360,386$3.63$4.15+$1.9M
I
INDV
INDIVIOR PLC5.06%$5.2M350,000$10.67$14.74+$2.3M

Options Positions (1)

TickerSecurityActionTypeNotional ValueContractsUnderlying PricePremium PaidChange (Contracts)Change (Value)
V
VSTM
VERASTEM INCNew
Call
$415.0K1,000$4.15$4.15+1,000+$415.0K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+67.7%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+21.8%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+7.1%
ORTHOPEDIC, PROSTHETIC & SURGICAL APPLIANCES & SUPPLIES
+1.3%
IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES
+0.7%