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Stonepine Capital Management, LLC

CIK:0001440771
Hedge Fund
$103M AUM
59 holdings
Bend, OR, United States
Founded:2006
6 employees
Latest filing:Jun 30, 2025

Stonepine Capital Management, LLC is a US-based hedge fund manager headquartered in Bend, Oregon. Founded in 2006, the firm principally invests in equity and equity-related securities, with an employee count of approximately 6 professionals. Stonepine Capital Management primarily serves institutional investors and high-net-worth individuals, offering investment advisory services with a focus on value-driven public equities.

Investment Strategy

Stonepine Capital Management focuses on value-oriented investments in public equities, emphasizing long-term growth and capital appreciation. Their investment approach is centered on deep fundamental analysis to identify undervalued stocks, particularly in the small- and mid-cap sectors. The firm pursues positions that offer both potential upside and a margin of safety, with an opportunistic outlook across various sectors.

Latest 13F Filing Activity

Stonepine Capital Management, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 55 equity positions and 1 options positions with a total 13F market value of $102M. The fund increased holdings in Adma Biologics Inc., Acadia Pharmaceuticals Inc., Iteos Therapeutics Inc. among other positions. Stonepine Capital Management, LLC reduced exposure to Ani Pharmaceuticals Inc., Optinose Inc., Evolus Inc. among others.

Top Buys
A
ADMAADMA BIOLOGICS INC
+$13.6M
A
ACADACADIA PHARMACEUTICALS INC
+$4.7M
I
ITOSITEOS THERAPEUTICS INC
+$2.4M
I
INDVINDIVIOR PLC
+$2.3M
A
ARDXARDELYX INC
+$2.2M
Top Sells
A
ANIPANI PHARMACEUTICALS INC
-$11.1M
O
OPTNOPTINOSE INC
-$7.2M
E
EOLSEVOLUS INC
-$5.2M
U
URGNUROGEN PHARMA LTD
-$3.7M
A
AQSTAQUESTIVE THERAPEUTICS INC
-$3.0M

Top Holdings

A
ADMAADMA BIOLOGICS INC
+13.4%$13.7M
E
EOLSEVOLUS INC
+8.3%$8.4M
Z
ZVRAZEVRA THERAPEUTICS INC
+6.7%$6.8M
V
VSTMVERASTEM INC
+5.5%$5.6M
I
INDVINDIVIOR PLC
+5.1%$5.2M

Equity Positions (55)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
ADMA BIOLOGICS INC13.40%$13.7M750,000$2.47$18.21+$13.6M
EVOLUS INC8.28%$8.4M916,500$7.64$9.21-$5.2M
ZEVRA THERAPEUTICS INC6.70%$6.8M775,620$7.28$8.81+$2.0M
VERASTEM INC5.54%$5.6M1,360,386$3.63$4.15+$1.9M
INDIVIOR PLC5.06%$5.2M350,000$10.67$14.74+$2.3M

Options Positions (1)

TickerSecurityActionTypeNotional ValueContractsUnderlying PricePremium PaidChange (Contracts)Change (Value)
VERASTEM INCNew
Call
$415.0K1,000$4.15$4.15+1,000+$415.0K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+71.3%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+16.1%
SURGICAL & MEDICAL INSTRUMENTS & APPARATUS
+4.0%
SERVICES-COMMERCIAL PHYSICAL & BIOLOGICAL RESEARCH
+3.4%
ELECTROMEDICAL & ELECTROTHERAPEUTIC APPARATUS
+1.3%