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Blue Water Life Science Advisors, LP

CIK:0001789778
Investment Adviser
$144M AUM
8 holdings
Larkspur, CA, United States
Founded:2019
6 employees
Latest filing:Jun 30, 2025

Blue Water Life Science Advisors, LP is a California-based investment adviser specializing in life sciences, owned and managed by Nathaniel T. Cornell. The firm was established in 2019 and operates as a limited partnership, focusing on institutional-level investment management primarily in the healthcare and biotechnology sectors. It serves institutional clients and high-net-worth individuals, with headquarters in Larkspur, California. The firm is registered with the SEC.

Investment Strategy

Blue Water Life Science Advisors, LP pursues a concentrated, research-driven investment approach focused on life sciences, healthcare, and biotechnology. The firm invests across public equities in these sectors, seeking differentiated opportunities through deep scientific and industry analysis. Portfolio construction emphasizes high-conviction positions in companies with strong growth prospects, innovative products, or significant market potential within the life sciences and healthcare fields.

Latest 13F Filing Activity

Blue Water Life Science Advisors, LP filed their most recent 13F report on Jun 30, 2025 disclosing 8 equity positions with a total 13F market value of $126M. The fund increased holdings in 10x Genomics Inc-class A, Adaptive Biotechnologies Cor, Personalis Inc. among other positions. Blue Water Life Science Advisors, LP reduced exposure to Guardant Health Inc., Natera Inc., Akoya Biosciences Inc. among others.

Top Buys
T
TXG10X GENOMICS INC-CLASS A
+$12.7M
A
ADPTADAPTIVE BIOTECHNOLOGIES COR
+$9.1M
P
PSNLPERSONALIS INC
+$6.9M
G
GHGUARDANT HEALTH INC
-$6.7M
Q
QTRXQUANTERIX CORP
+$3.9M
Top Sells
T
TXG10X GENOMICS INC-CLASS A
+$12.7M
A
ADPTADAPTIVE BIOTECHNOLOGIES COR
+$9.1M
P
PSNLPERSONALIS INC
+$6.9M
G
GHGUARDANT HEALTH INC
-$6.7M
Q
QTRXQUANTERIX CORP
+$3.9M

Top Holdings

N
NTRANATERA INC
+22.3%$28.1M
A
ADPTADAPTIVE BIOTECHNOLOGIES COR
+19.8%$25.0M
G
GHGUARDANT HEALTH INC
+18.1%$22.8M
C
CDNACAREDX INC
+11.2%$14.1M
T
TXG10X GENOMICS INC-CLASS A
+10.1%$12.7M

Equity Positions (8)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
NATERA INC22.26%$28.1M166,494$78.28$168.94-$1.4M
ADAPTIVE BIOTECHNOLOGIES COR19.78%$25.0M2,145,145$5.12$11.65+$9.1M
GUARDANT HEALTH INC18.09%$22.8M439,047$53.65$52.04-$6.7M
CAREDX INC11.20%$14.1M724,014$17.83$19.54+$1.3M
10X GENOMICS INC-CLASS A10.09%$12.7M1,100,720$11.58$11.58+$12.7M

Industry Allocation

SERVICES-MEDICAL LABORATORIES
+60.6%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+29.3%
SERVICES-COMPUTER PROGRAMMING, DATA PROCESSING, ETC.
+5.3%
LABORATORY ANALYTICAL INSTRUMENTS
+4.7%