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ALUMIS (ALMS)

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Earnings summaries and quarterly performance for ALUMIS.

Research analysts covering ALUMIS.

Recent press releases and 8-K filings for ALMS.

Alumis Reports Positive Phase 3 Psoriasis Data for Envudeucitinib and Provides Updates on Regulatory Filings and SLE Trial
ALMS
Product Launch
New Projects/Investments
  • Alumis announced positive top-line Phase 3 data for envudeucitinib in psoriasis in January, showing 74% average PASI 75 and 59% sPGA 0/1 at week 16, and 65% average PASI 90 and over 40% average PASI 100 at week 24, with a safety profile consistent with Phase 2.
  • The company plans to submit the New Drug Application (NDA) for envudeucitinib in psoriasis in the second half of the year, following the receipt of 48-week data by mid-year.
  • For commercialization of envudeucitinib, Alumis anticipates a partnership given the broad potential of the TYK2 franchise across multiple indications globally.
  • A pivotal Phase 2b trial for envudeucitinib in Systemic Lupus Erythematosus (SLE), which has completed enrollment, is expected to read out data in the third quarter of this year.
2 days ago
Alumis Reports Positive Phase 3 Psoriasis Data and Upcoming SLE Trial Readout
ALMS
Product Launch
New Projects/Investments
  • Alumis announced positive top-line Phase 3 data for envudeucitinib in psoriasis, achieving an average PASI 75 of 74% and sPGA 0/1 of 59% at week 16, with safety consistent with Phase 2.
  • The company plans to submit its NDA for envudeucitinib in psoriasis in the second half of the year, following the availability of 48-week data by mid-year.
  • A Phase 2b trial for envudeucitinib in Systemic Lupus Erythematosus (SLE), designed as a pivotal trial, completed enrollment last summer and is expected to read out data in the third quarter of this year.
  • Alumis anticipates partnering for the global commercialization of envudeucitinib, especially considering its potential for up to 20 indications across the TYK2 franchise.
2 days ago
Alumis Discusses Positive Phase 3 Psoriasis Data and Future Milestones for Envudeucitinib
ALMS
Product Launch
New Projects/Investments
  • Alumis announced positive top-line Phase 3 data for envudeucitinib in psoriasis, achieving an average PASI 75 of 74% and sPGA 0/1 of 59% at week 16, with a safety profile consistent with Phase II.
  • The company plans to submit its New Drug Application (NDA) for envudeucitinib in psoriasis in the second half of 2026, following the availability of 48-week data by mid-2026.
  • Data from the Phase 2b pivotal trial for envudeucitinib in Systemic Lupus Erythematosus (SLE) is expected to read out in the third quarter of 2026.
  • Alumis intends to pursue a partnership for the commercialization of envudeucitinib, recognizing the broad potential of its TYK2 franchise.
  • A once-a-day (QD) formulation for envudeucitinib is under development as a life cycle extension, but it will not be part of the initial launch.
2 days ago
Alumis Discusses Positive Psoriasis Phase 3 Data and Upcoming Milestones
ALMS
Guidance Update
New Projects/Investments
  • Alumis reported strong Phase 3 results for its TYK2 inhibitor, envudeucitinib, in psoriasis, demonstrating significant PASI score reductions and a fast onset, with an abstract submitted for AAD.
  • The company plans to file a New Drug Application (NDA) for envudeucitinib in psoriasis in the second half of 2026, pending durability and maintenance data from the ONWARD 3 study in Q2/early Q3 2026.
  • Phase IIb results for the Systemic Lupus Erythematosus (SLE) program, designed as a pivotal study, are anticipated in Q3 2026.
  • Alumis has a strong financial position with over $630 million in cash, providing a runway into the fourth quarter of 2027.
Feb 12, 2026, 2:00 PM
Alumis Provides Update on Psoriasis and Lupus Programs, and Financial Outlook
ALMS
Product Launch
New Projects/Investments
Guidance Update
  • Alumis reported positive Phase III results for envudeucitinib in psoriasis, highlighting strong efficacy with PASI 75 in the 70s, PASI 90 at 65%, and PASI 100 over 40% at week 24, alongside a fast onset and consistent safety profile.
  • The company expects to file a New Drug Application (NDA) for envudeucitinib in psoriasis in the second half of 2026, following the availability of withdrawal study data in Q2/early Q3 2026.
  • Results from the pivotal Phase IIb study of envudeucitinib in Systemic Lupus Erythematosus (SLE) are anticipated in Q3 2026.
  • Alumis has a strong financial position with just over $630 million in cash, providing a runway into the fourth quarter of 2027.
  • While capable of independent market preparation, Alumis considers a partnership more likely for the global optimization of its TYK2 franchise across numerous potential indications.
Feb 12, 2026, 2:00 PM
Alumis Discusses Psoriasis Phase 3 Results, Upcoming Lupus Data, and Financial Runway
ALMS
New Projects/Investments
Guidance Update
  • Alumis announced strong Phase 3 results for its peripheral TYK2 inhibitor, envudeucitinib, in psoriasis, reporting PASI 75 in the 70s, PASI 90 of about 65%, and PASI 100 over 40% at week 24, with a fast onset and consistent safety profile. The company expects to file an NDA in the second half of 2026, following the availability of durability and maintenance data from the ONWARD 3 study in Q2/early Q3 2026.
  • The company anticipates Phase 2b results for its lupus (SLE) program in the third quarter of 2026; this study is designed as a pivotal trial with over 400 patients, aiming for a 15% improvement in BICLA for success. Alumis also intends to start a study for its brain-penetrant TYK2 in MS in the first half of 2026.
  • Alumis has just over $630 million in cash, providing a runway into the fourth quarter of 2027. The company believes a partnership is more likely for global commercialization to optimize its TYK2 franchise across multiple indications, though launching alone is considered possible.
Feb 12, 2026, 2:00 PM
Alumis closes upsized public offering
ALMS
  • Alumis Inc. announced the closing of its upsized underwritten public offering, which included the full exercise of the underwriters' option to purchase additional shares.
  • The offering involved the sale of 20,297,500 shares of common stock at a price of $17.00 per share.
  • This transaction generated approximately $345.1 million in gross proceeds for Alumis.
Jan 9, 2026, 9:05 PM
Alumis Inc. Announces Public Offering and Preliminary Cash Balance
ALMS
  • Alumis Inc. entered into an underwriting agreement on January 7, 2026, for a public offering of 20,297,500 shares of its voting common stock, which includes 2,647,500 shares from a fully exercised option.
  • The shares were offered at $17.00 per share, with the offering expected to close on January 9, 2026, generating approximately $345.1 million in gross proceeds for the company before deductions.
  • As of December 31, 2025, the company reported preliminary unaudited cash, cash equivalents, and marketable securities of approximately $308.6 million.
Jan 9, 2026, 11:02 AM
Alumis Prices Upsized Public Offering of Common Stock
ALMS
  • Alumis Inc. (Nasdaq: ALMS) announced the pricing of an upsized underwritten public offering of 17,650,000 shares of its common stock.
  • The shares are priced at $17.00 per share, expected to generate approximately $300.0 million in gross proceeds for Alumis.
  • All shares in the offering are being sold by Alumis.
  • The offering is expected to close on January 9, 2026.
  • Alumis has granted the underwriters a 30-day option to purchase up to an additional 2,647,500 shares of common stock.
Jan 8, 2026, 3:52 AM
Alumis Announces Proposed Public Offering of Common Stock
ALMS
  • Alumis Inc. announced plans on January 6, 2026, to commence an underwritten public offering of $175.0 million of its common stock.
  • The company expects to grant the underwriters a 30-day option to purchase up to an additional $26.25 million of shares of its common stock.
  • All shares in the proposed offering are being offered by Alumis.
  • Morgan Stanley, Leerink Partners, Cantor, and Wells Fargo Securities are acting as joint book-running managers for the offering.
Jan 6, 2026, 9:12 PM