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Andres Ruiz Briseno

Chief Accounting Officer at IDEAYA Biosciences
Executive

About Andres Ruiz Briseno

Andres Ruiz Briseno is 39 and currently serves as Chief Accounting Officer (CAO) of IDEAYA Biosciences, having been the company’s principal financial officer since December 7, 2023 and principal accounting officer since July 1, 2023; he became CAO on March 1, 2025, with a CFO appointed effective May 2025 to succeed the principal financial officer role . He holds a B.S. in Business Administration (Corporate Financial Management) from San Jose State University and is a Certified Public Accountant licensed in California . Company pay-versus-performance disclosures show cumulative TSR and cash balance trends used in linking compensation to performance; IDEAYA identified “Cash, Cash Equivalents and Marketable Securities” as the most important measure in 2024 .

Metric2021202220232024
Company TSR (Value of $100)168.86 129.79 254.14 183.57
Net Loss ($000s)(49,762) (58,655) (112,961) (274,477)
Cash, Cash Equivalents & Marketable Securities ($MM)368.1 373.1 623.6 1,082.2

Past Roles

OrganizationRoleYearsStrategic Impact
IDEAYA BiosciencesChief Accounting Officer (Principal Financial & Accounting Officer)Mar 2025–presentElevated to CAO; maintained PFO until CFO appointment effective May 2025 .
IDEAYA BiosciencesSVP, Head of Finance & Investor Relations (Principal Financial Officer)Jul 2023–Feb 2025Led finance and IR; served as PFO from Dec 2023 .
IDEAYA BiosciencesVP, Head of Business Operations & Investor RelationsNov 2021–Jun 2023Built operations/IR capabilities .
IDEAYA BiosciencesFinance roles incl. VP, FinanceAug 2016–Jul 2021Early finance leadership at IDEAYA .

External Roles

OrganizationRoleYearsStrategic Impact
Neumora TherapeuticsSVP, Finance & Principal Accounting OfficerJul–Oct 2021Led finance and accounting at a biotech peer .
Pharmacyclics, Inc.FP&A roles incl. Associate DirectorPrior to 2016Oncology biotech finance experience .
Theravance, Inc.Finance rolesPrior to PharmacyclicsBiopharma finance exposure .
PricewaterhouseCoopersAudit & Assurance (Life sciences & VC focus)Prior to TheravanceCPA-track audit across LS/VC clients .

Fixed Compensation

YearBase Salary ($)Target Bonus %Actual Bonus Paid ($)All Other Compensation ($)
2023357,500 35% 125,125 15,000
2024382,500 35% 133,875 15,600

Notes:

  • All Other Compensation for Andres includes $1,800 cell phone allowance and $13,800 401(k) employer match (2024) .

Performance Compensation

Annual Cash Incentive – 2024 Structure and Outcome

Metric ComponentWeightingTargetActualPayout ($)Vesting
Corporate Objectives (clinical/preclinical 70%; corporate development 30%)70% of bonus100% of target 100% achieved (Board/Comp Committee, Feb 2025) Included in $133,875 Cash (no vest)
Individual Performance Assessment30% of bonus100% of target 100% achieved (Feb 2025) Included in $133,875 Cash (no vest)

Program detail:

  • Corporate goals spanned IDE397, IDE161, Pol Theta, Werner Helicase and early discovery; corporate development included darovasertib US launch readiness, balance sheet enhancement, investor base, and infrastructure .
  • Board determined corporate objectives at 100% of target, also considering IDE849 and IDE034 in-license agreements and balance sheet enhancement .

Equity Awards – Grants and Vesting

Grant DateAward TypeSharesExercise Price ($/sh)Grant-Date Fair Value ($)VestingExpiration
3/1/2024Stock Option85,000 46.22 2,823,819 25% at 1-year, then 1/48 monthly 3/1/2034

Option exercises and realized value in 2024:

NameShares Exercised (#)Value Realized ($)
Andres Ruiz Briseno

Equity Ownership & Alignment

Ownership Measure (as of 3/31/2025)Count/Amount% of Outstanding
Outstanding Shares Beneficially Owned25,213 <1%
Shares Exercisable Within 60 Days102,867 <1%
Total Beneficial Ownership128,080 <1%

Outstanding stock options by grant (as of 12/31/2024):

Vesting CommencementExercisable (#)Unexercisable (#)Exercise Price ($)Expiration
11/1/202146,246 13,754 22.30 11/1/2031
3/1/202220,958 7,792 12.86 3/1/2032
2/24/202320,360 22,140 17.04 2/24/2033
6/29/20237,965 14,535 23.23 6/29/2033
3/1/202485,000 46.22 3/1/2034

Alignment policies:

  • IDEAYA prohibits pledging of company securities and hedging/monetization transactions (including margin accounts, zero-cost collars, forward sale contracts) under its Insider Trading Compliance Policy .
  • Clawback: The company maintains a Policy for Recovery of Erroneously Awarded Compensation for executive officers in connection with restatements .

Employment Terms

Severance and change-in-control economics (as of 12/31/2024):

ScenarioCash SeveranceTarget BonusHealthcare CoverageEquity Vesting
Involuntary termination without cause or resignation for good reason (outside CIC period)$286,875 $25,965
Involuntary termination without cause or resignation for good reason (within CIC period)$382,500 $133,875 $34,620 $996,775 (unvested in-the-money options)

Contractual framework:

  • For non-PEO NEOs (including Andres), outside CIC: lump sum equal to 75% of annual base salary plus up to 9 months of healthcare; within CIC (defined as 3 months pre- to 12 months post-close): lump sum equal to 100% of annual base salary and target annual incentive, up to 12 months healthcare, and full acceleration of equity awards (double-trigger) . If options are not assumed/substituted in a change in control, acceleration may occur at close (single-trigger for non-assumed awards) .
  • Definitions of “cause,” “good reason,” “change in control,” and “good reason process” are specified; “good reason” includes material salary reduction not broadly applied, relocation increasing commute >75 miles, or material reduction in duties following the cure process .
  • No 280G/4999 excise tax gross-ups provided .

Compensation Structure Analysis

  • Cash vs equity mix: 2024 compensation included base salary ($382,500), annual cash bonus ($133,875), and a significant option grant fair value ($2,823,819), indicating a heavy equity-at-risk component via options with four-year vesting .
  • Performance metrics: Annual bonus tied to corporate goals (clinical/preclinical 70%; corporate development 30%) and individual performance (30% of bonus for NEOs), both assessed at 100% for 2024; the company-selected pay-versus-performance measure was cash/cash equivalents/marketable securities .
  • Equity award practices: Options vest 25% at the first anniversary then monthly, aligning retention incentives; the company states awards are not timed around MNPI releases .

Related Party Transactions and Governance

  • No related party transactions disclosed involving Andres; the company maintains a related person transaction approval policy overseen by the Audit Committee .
  • Compensation Committee membership (independent): Jeffrey L. Stein (Chair), Catherine Mackey, Terry J. Rosen, Wendy L. Yarno; uses a written charter and oversees executive compensation and succession planning .

Investment Implications

  • Alignment and retention: Significant unvested options (e.g., 85,000 from 2024 at $46.22) vest monthly after the first anniversary, creating ongoing retention incentives; Andres did not exercise options in 2024, limiting near-term selling pressure signals . Pledging and hedging are prohibited, reducing alignment risk from collateralization or derivatives .
  • Change-of-control dynamics: Double-trigger full acceleration within the CIC period plus salary/bonus severance could make finance leadership retention during M&A manageable; single-trigger acceleration applies if options are not assumed, which can influence transaction structuring considerations .
  • Pay-for-performance linkage: Annual bonus tied to operational milestones and individual performance (both achieved at 100% for 2024), and the company emphasized cash/cash equivalents/marketable securities as the key pay-versus-performance measure, reflecting balance sheet strength as a core value driver in pre-revenue biotech .
  • Ownership: Beneficial ownership is modest (<1%), with 102,867 options exercisable within 60 days as of March 31, 2025—monitor upcoming monthly vesting for potential incremental selling pressure, though 2024 activity was nil .