Sign in

Robert Epstein

Director at ILLUMINAILLUMINA
Board

About Robert S. Epstein

Independent director since 2012, age 69, and a physician-executive with deep expertise in market access, reimbursement, and evidence generation for diagnostics. Education includes a B.S. and M.D. from the University of Michigan (six-year program) and an M.S. in Preventive Medicine from the University of Maryland. He currently serves as CEO & Co‑Founder of Epstein Health LLC and brings significant life sciences and regulatory domain knowledge to ILMN’s board .

Past Roles

OrganizationRoleTenureCommittees/Impact
Medco/UBCChief Medical Officer; later Chief R&D Officer and President, Medco‑UBC (global pharma services focused on market access/personalized medicine)CMO 1997–2010; Chief R&D Officer & President 2010–2012Led personalized medicine testing, outcomes research; Medco ranked #3 most innovative by Fortune for this work
Epstein Health LLCCEO & Co‑Founder2012–presentAdvises PE investors and healthcare tech companies on innovation, market access

External Roles

OrganizationRoleSinceNotes
Veracyte, Inc.Director; ChairDirector since 2015; Chair since 2023Public genomics diagnostics company; board leadership role
Fate Therapeutics, Inc.DirectorSince 2014Public biotech company
Tasso, Inc.DirectorSince 2023Private company
Diadem srlDirectorSince 2022Private company
PinkDx, Inc.DirectorSince 2024Private company
Proteus Digital HealthDirector2013–2020Prior private role
Decipher BiosciencesChairman2019–2021Prior private role

Board Governance

CommitteeRole2024 Meetings
CompensationMember7
Nominating/Corporate GovernanceMember5
  • Independence: Board determined Dr. Epstein is independent under Nasdaq listing standards .
  • Attendance: Each director attended at least 75% of aggregate Board and relevant committee meetings in fiscal 2024; Board held 9 meetings; executive sessions of independent directors were regularly held .
  • Committee effectiveness: Compensation Committee uses an independent consultant (Aon); 2024 review found no consultant conflicts; oversight includes director pay and executive comp governance .
  • Stockholder engagement: Board conducted proactive outreach in fall 2024 to holders of >50% of shares .
  • Structural safeguards: Independent Chair; all standing committees 100% independent; clear risk oversight allocation across committees .

Fixed Compensation

ComponentProgram Terms (FY 2024)Epstein Actual (FY 2024)
Annual Board retainer (cash)$75,000 Included in $101,126 total cash fees
Committee membership fees (cash)Compensation: $15,000 member; Nominating/Corporate Governance: $10,000 member Included in $101,126 total cash fees
Committee chair fees (cash)Comp Chair $25,000; Nom/Gov Chair $15,000 (not applicable to Epstein) $0 (not a chair)
Meeting feesNone disclosed N/A
Total cash fees$101,126

Performance Compensation

Equity AwardGrant DateQuantityGrant‑Date Fair ValueVestingSettlement
Annual RSUsMay 16, 20242,675$300,114Vests on the earlier of first anniversary or day prior to next annual meeting, subject to continued service Director may elect cash, stock, or combination
Stock optionsNone grantedN/A
PSUs/performance metricsNot applicable to director awardsN/A
  • Director equity is time‑based RSUs; no performance metrics or option awards are used for non‑employee directors in 2024 .

Other Directorships & Interlocks

CompanyRoleIndustry Overlap
Veracyte, Inc.ChairDiagnostics/genomics adjacent to ILMN’s markets
Fate Therapeutics, Inc.DirectorBiotech (cell therapy)
  • Related-party transactions: None occurred in fiscal 2024; Compensation Committee reported no interlocks or related-party transactions involving its members (including Dr. Epstein) in 2024 .

Expertise & Qualifications

  • Reimbursement and payer evidence: Extensive practical knowledge of how molecular diagnostic tests are reimbursed and evaluated by payers/evidentiary authorities .
  • Scientific/clinical markets: Deep life sciences and regulatory experience supporting ILMN’s shift to clinical and FDA‑regulated markets .
  • Skills matrix: Technology & innovation, life sciences, public company executive, risk oversight/management indicated among his competencies .
  • Publications and leadership: 100+ peer‑reviewed articles; prior leadership in pharmacoeconomics (ISPOR president) .
  • Education: B.S. & M.D. (University of Michigan); M.S. Preventive Medicine (University of Maryland) .

Equity Ownership

MetricValueAs‑of
Common stock beneficially owned18,359 shares (<1%) March 26, 2025
Unvested RSUs outstanding2,675 December 29, 2024
Hedging/pledgingProhibited by ILMN Insider Trading Policy for directors and executives Policy current
  • Stock ownership guidelines: Non‑employee directors required to hold 5x annual retainer; unvested RSUs count toward compliance; PSUs/options do not .

Governance Assessment

  • Strengths

    • Independent director with relevant domain expertise for ILMN’s clinical expansion; active on Compensation and Nominating/Governance committees .
    • Strong governance architecture: independent Chair, independent committees, clawback policy aligned with Dodd‑Frank/Nasdaq, anti‑hedging/pledging policy .
    • Director pay structure balanced with majority equity via annual RSUs; program reviewed by independent consultant; proposed cap on total non‑employee director compensation ($1.0M first year; $750k thereafter) enhances pay governance .
  • Watch items

    • External chair role at Veracyte (diagnostics) warrants ongoing monitoring for potential competitive or transactional overlaps; ILMN disclosed no related‑party transactions in 2024 and Compensation Committee reported no interlocks, which mitigates near‑term conflict risk .
    • Attendance disclosures are aggregate (≥75% for all directors) rather than director‑specific; continued tracking of individual attendance would further enhance transparency .
  • Overall signal: Board effectiveness and independence appear solid, with robust committee refreshes and risk oversight; compensation governance (ownership guidelines, clawback, anti‑hedging) supports alignment with shareholders .