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ILLUMINA (ILMN)

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Earnings summaries and quarterly performance for ILLUMINA.

Research analysts who have asked questions during ILLUMINA earnings calls.

David Westenberg

David Westenberg

Piper Sandler

4 questions for ILMN

Also covers: ADPT, AKYA, BLLN +13 more
Tycho Peterson

Tycho Peterson

Jefferies

4 questions for ILMN

Also covers: A, AVTR, BIO +22 more
Vijay Kumar

Vijay Kumar

Evercore ISI

4 questions for ILMN

Also covers: A, ABT, AVTR +21 more
CN

Conor Noel McNamara

RBC Capital Markets

3 questions for ILMN

Also covers: AVTR, BIO, HOLX +6 more
Daniel Brennan

Daniel Brennan

TD Cowen

3 questions for ILMN

Also covers: A, ADPT, AVTR +24 more
Douglas Schenkel

Douglas Schenkel

Wolfe Research, LLC

3 questions for ILMN

Also covers: A, AVTR, BRKR +21 more
PS

Puneet Souda

Leerink Partners

3 questions for ILMN

Also covers: A, ABCL, BRKR +20 more
DA

Daniel Arias

Stifel, Nicolaus & Company, Incorporated

2 questions for ILMN

Also covers: A, AVTR, CDXS +15 more
KM

Kyle Mikson

Canaccord Genuity

2 questions for ILMN

Also covers: AKYA, BDSX, CSTL +12 more
Patrick Donnelly

Patrick Donnelly

Citi

2 questions for ILMN

Also covers: A, AVTR, BIO +21 more
SN

Subhalaxmi Nambi

Guggenheim Securities

2 questions for ILMN

Also covers: AKYA, BRKR, CSTL +15 more
SJ

Sung Ji Nam

Scotiabank

2 questions for ILMN

Also covers: ADPT, BDSX, BNGO +9 more
BM

Ben Miller

Stephens Inc.

1 question for ILMN

Dan Arias

Dan Arias

Stifel Financial Corp.

1 question for ILMN

Also covers: A, GH, MRVI +9 more
DL

Daniel Leonard

Stifel Financial Corp.

1 question for ILMN

Also covers: A, AVTR, BIO +15 more
Doug Schenkel

Doug Schenkel

Wolfe Research LLC

1 question for ILMN

Also covers: A, AVTR, BRKR +15 more
EB

Eve Burstein

Goldman Sachs

1 question for ILMN

Also covers: EXAS, GH, PACB +1 more
Jack Meehan

Jack Meehan

Nephron Research LLC

1 question for ILMN

Also covers: A, AVTR, BIO +17 more
Michael Ryskin

Michael Ryskin

Bank of America Merrill Lynch

1 question for ILMN

Also covers: A, ALGN, AVTR +28 more
Rachel Vatnsdal

Rachel Vatnsdal

JPMorgan Chase & Co.

1 question for ILMN

Also covers: A, AKYA, AVTR +11 more
RV

Rachel Vatnsdal Olson

JPMorgan

1 question for ILMN

Also covers: A, ADPT, AKYA +14 more
Subbu Nambi

Subbu Nambi

Guggenheim Securities

1 question for ILMN

Also covers: BOLD, BRKR, CARS +16 more
TS

Tejas Savant

Morgan Stanley

1 question for ILMN

Also covers: ADPT, AKYA, AVTR +19 more

Recent press releases and 8-K filings for ILMN.

Illumina Reports Preliminary FY25 Results and Outlines FY27 Targets
ILMN
Earnings
Guidance Update
Share Buyback
  • Illumina reported preliminary FY25 revenue of ~$4.34 billion (flat year-over-year constant currency) and non-GAAP diluted EPS of $4.76-$4.79, achieving a non-GAAP operating margin of ~23%.
  • For Q4 2025, preliminary results indicate revenue of ~$1.155 billion (approximately 4% year-over-year growth constant currency) and non-GAAP diluted EPS ranging from $1.27 to $1.30.
  • The company achieved key NovaSeq X milestones and observed an acceleration in Ex-China Sequencing Consumables YoY Growth to 20% in Q4 2025, driven by 11% growth in Research & Applied and 0% in Clinical.
  • Illumina has set FY27 targets including high-single-digit (HSD) revenue growth (ex-China), over 500 basis points of operating margin expansion, and double-digit to teens EPS growth.
  • The company generated ~$1.0 billion in free cash flow for the last twelve months as of September 28, 2025, and executed ~$740 million in share buybacks during FY25.
1 day ago
Illumina Reports Strong Q4 and Full-Year 2025 Preliminary Results, Driven by Clinical Market Growth and NovaSeq X Adoption
ILMN
Earnings
Revenue Acceleration/Inflection
New Projects/Investments
  • Illumina reported preliminary Q4 2025 revenue growth of 4% on a constant currency basis, or 7% excluding China, with Q4 earnings per share (EPS) in the range of $1.27-$1.30. This contributed to a full-year 2025 EPS of approximately $4.76-$4.79, representing over 15% earnings growth.
  • The company placed over 95 NovaSeq X instruments in Q4 2025, and by year-end 2025, the NovaSeq X accounted for approximately 80% of high-throughput gigabases shipped, reflecting strong customer adoption, particularly in clinical markets.
  • Illumina returned to growth in 2025, expanding margins by approximately 200 basis points and growing EPS by 15%, with expectations to continue this progress in 2026, driven by the clinical market.
  • Strategic initiatives include expanding into multiomics with new solutions and the launch of BioInsight, aimed at accelerating drug discovery through large-scale data analysis and AI, supported by approximately $1 billion in annual cash flow and a commitment to share repurchases.
1 day ago
Illumina Reports Strong Preliminary Q4 2025 Results and Strategic Progress
ILMN
Earnings
Revenue Acceleration/Inflection
New Projects/Investments
  • Illumina announced strong preliminary Q4 2025 results, with revenue growing 4% on a constant currency basis and 7% excluding China, and Q4 EPS between $1.27 and $1.30, leading to full-year EPS growth of over 15%.
  • The NovaSeq X transition is advancing, with the instrument representing approximately 80% of high-throughput gigabases shipped by year-end 2025, and clinical consumables growth ex-China reaching 20% in Q4.
  • The company is expanding its ecosystem with new multi-omics solutions and the launch of BioInsights, aimed at accelerating drug discovery through large-scale data and AI.
  • Clinical markets are a primary growth driver, accounting for roughly 60% of consumables revenue and experiencing sequencing volume growth above 30%, though the academic and research market is anticipated to be muted in 2026.
  • Illumina emphasizes disciplined capital allocation, prioritizing investment in innovation, targeted acquisitions, and shareholder returns, having repurchased $740 million by June 2025.
1 day ago
Illumina Announces Preliminary Q4 and Full-Year 2025 Results, Highlights Strategic Growth
ILMN
Earnings
Guidance Update
New Projects/Investments
  • Illumina reported preliminary Q4 2025 revenue growth of 4% on a constant currency basis and 7% excluding China, with Q4 earnings per share (EPS) in the range of $1.27 to $1.30.
  • For the full year 2025, EPS is expected to be approximately $4.76 to $4.79, representing over 15% earnings growth and a return to company growth with 200 basis points margin expansion.
  • This performance was driven by strong NovaSeq X instrument placements (more than 95 X's) and consumables, particularly from clinical customers, which now account for roughly 60% of sequencing consumables and saw 20% growth ex-China in Q4.
  • The company is focused on strategic growth pillars, including expanding the NGS ecosystem, deepening biological discovery through multi-omics (e.g., single-cell solution, Illumina Protein Prep, spatial solution), and scaling services, data, and software with the new BioInsights business.
  • Capital allocation priorities include investing in innovation, pursuing targeted bolt-on acquisitions, and returning excess capital to shareholders, with $740 million returned via share repurchases by June 2025.
1 day ago
Illumina Introduces Billion Cell Atlas to Accelerate AI and Drug Discovery
ILMN
Product Launch
New Projects/Investments
Partnerships
  • Illumina introduced the Billion Cell Atlas, described as the world's largest genome-wide genetic perturbation dataset, aimed at accelerating drug discovery through AI across the pharmaceutical ecosystem.
  • This Atlas is the initial phase of a program to build a 5 billion cell atlas over three years, designed to capture how 1 billion individual cells respond to genetic changes via CRISPR across more than 200 disease-relevant cell lines.
  • AstraZeneca, Merck, and Eli Lilly and Company are leading as founding participants in an alliance framework to leverage the Atlas for validating genetic targets and training advanced AI models.
  • The Billion Cell Atlas is the first data product to emerge from Illumina's new BioInsight business, which is focused on providing foundational technologies and datasets for AI in pharma.
1 day ago
Illumina Announces Preliminary Q4 and Fiscal Year 2025 Financial Results
ILMN
Earnings
Guidance Update
  • Illumina, Inc. released preliminary unaudited financial results for the fourth quarter and fiscal year 2025 on January 13, 2026.
  • For Q4 2025, preliminary revenue was approximately $1.155 billion, representing a 5% increase from Q4 2024, with GAAP diluted EPS between $2.14 and $2.17 and non-GAAP diluted EPS between $1.27 and $1.30.
  • For fiscal year 2025, preliminary revenue was approximately $4.34 billion, which was flat compared to 2024, with GAAP diluted EPS ranging from $5.42 to $5.45 and non-GAAP diluted EPS from $4.76 to $4.79.
  • These preliminary figures are subject to final accounting and audit procedures, with the full results anticipated on February 5, 2026.
1 day ago
Illumina Announces Preliminary Q4 and Fiscal Year 2025 Financial Results
ILMN
Earnings
Guidance Update
  • Illumina announced preliminary unaudited revenue of approximately $1.155 billion for the fourth quarter of 2025, marking a 5% increase from Q4 2024.
  • For fiscal year 2025, the company reported preliminary unaudited revenue of approximately $4.34 billion, which was flat compared to 2024.
  • Preliminary GAAP diluted earnings per share (EPS) for Q4 2025 ranged from $2.14 to $2.17, with non-GAAP diluted EPS between $1.27 and $1.30.
  • Preliminary GAAP diluted EPS for fiscal year 2025 ranged from $5.42 to $5.45, and non-GAAP diluted EPS was between $4.76 and $4.79.
  • Illumina expects to report its full fourth quarter and fiscal year 2025 results on February 5, 2026, and these preliminary results are subject to adjustment.
1 day ago
Illumina: RNA Sequencing Services Market Opportunity Outlook, 2035
ILMN
New Projects/Investments
Revenue Acceleration/Inflection
  • The RNA Sequencing Service Market is projected to grow from $3.3 billion in 2023 to $7.5 billion by 2035, demonstrating an 8.4% compound annual growth rate (CAGR).
  • Illumina is identified as the predominant platform for small RNA and mRNA sequencing within this expanding market.
  • Next-generation sequencing (NGS) methods are expected to maintain their dominance, capturing approximately 95% of the market share, with hospitals representing 45% of the end-user market and North America holding 37% of the geographical market share.
  • The sector has received substantial support, with $1.03 billion in grants allocated to drive research and innovation.
2 days ago
Illumina announces Chief Medical Officer appointment and Chief Commercial Officer departure
ILMN
Management Change
Hiring
  • Illumina appointed Dr. Eric Green as Chief Medical Officer (CMO), effective February 2.
  • Everett Cunningham, Chief Commercial Officer, will resign effective January 16, 2026, to become CEO of a life science tools company.
  • Jacob Thaysen, CEO, will serve as interim chief commercial officer until a permanent successor is named.
6 days ago
Illumina Completes $500 Million Notes Offering
ILMN
Debt Issuance
M&A
New Projects/Investments
  • Illumina, Inc. completed a public offering of $500,000,000 aggregate principal amount of its 4.750% notes due 2030 on November 25, 2025.
  • The notes will accrue interest at 4.750% per annum, payable semi-annually, and will mature on December 12, 2030.
  • The net proceeds are expected to be used for general corporate purposes, including the potential repayment of its 5.800% notes due December 12, 2025, and the completion of the proposed acquisition of SomaLogic, Inc..
  • In the event of a Change of Control Triggering Event, Illumina will be required to offer to purchase the notes at 101% of the aggregate principal amount plus accrued and unpaid interest.
Nov 25, 2025, 10:06 PM