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Spike Loy

Independent Director at MoonLake Immunotherapeutics
Board

About Spike Loy

Spike Loy (age 44 as of April 22, 2025) is an Independent Director of MoonLake Immunotherapeutics (MLTX), serving since April 2022; he also sits on the board of MoonLake AG (subsidiary) since May 2021. He is a Managing Director at BVF Partners L.P. (since August 2009), and holds a J.D. from Harvard Law School and a B.A. in Human Biology with a minor in Economics from Stanford University .

Past Roles

OrganizationRoleTenureCommittees/Impact
GH Research PLC (Nasdaq: GHRS)DirectorOct 2020 – Mar 2022Biopharma board experience
MoonLake AG (subsidiary)DirectorMay 2021 – presentGovernance liaison to subsidiary board

External Roles

OrganizationRoleTenureNotes
BVF Partners L.P.Managing DirectorAug 2009 – presentBVF is MLTX’s largest holder; see interlock note below
Private biopharma companiesDirectorOngoingMultiple private boards (not named)

Board Governance

  • Committee assignments: Audit Committee member; Compensation Committee member; not a chair on any committee .
  • Independence: Board determined Loy is independent under Nasdaq rules; Audit and Compensation membership also meet the stricter independence criteria .
  • Attendance and engagement: Board met 4 times in 2024 (and 9 times in 2023); each director attended at least 75% of aggregate Board/committee meetings in periods served .
  • Governance structure context: MLTX has a classified board, supermajority vote requirements to amend MAA/remove directors, plurality voting for directors, and no special shareholder-called meetings between AGMs .

Fixed Compensation

Metric20232024
Annual Board cash retainer (program)$40,000 $40,000
Audit Committee member cash retainer (program)$7,500 $7,500
Compensation Committee member cash retainer (program)$5,000 $5,000
Chair premiums (for reference; not applicable to Loy)Audit Chair $17,500; Comp Chair $12,000; Board Chair $35,000 Audit Chair $17,500; Comp Chair $12,000; Board Chair $35,000
Fees earned or paid in cash (actual)$52,500 $52,500
Total director compensation (cash + equity)$277,491 $277,505

Performance Compensation

Equity Award Details20232024
Option grant dateJun 8, 2023 Jun 6, 2024
Options granted (shares)11,297 7,688
Fair value at grant (Black-Scholes)$224,991 $225,005
Vesting termsVests in full on earlier of 1-year anniversary or next AGM; or upon Change of Control; service requirement Same vesting terms; service requirement
Meeting feesNone disclosed; program uses retainers None disclosed; program uses retainers
  • No director-specific performance metrics tied to pay were disclosed; director equity is time-based (or AGM-date) vesting, with Change of Control acceleration .

Other Directorships & Interlocks

EntityNatureDetails
GH Research PLCPrior public company directorshipDirector Oct 2020 – Mar 2022
MoonLake AGSubsidiary boardDirector since May 2021; reimbursed for MoonLake AG board-related expenses
BVF Partners L.P.InterlockLoy is Managing Director; BVF-managed funds own ~31.1% of Class A (as of Mar 15, 2025); Loy must transfer to BVF Partners L.P. the economic benefit upon sale of shares issued from his option exercises

Expertise & Qualifications

  • Capital markets and life sciences investing expertise from BVF; biopharma board experience; legal training (Harvard J.D.) and scientific undergraduate background (Stanford Human Biology; Economics minor) .

Equity Ownership

MetricMar 15, 2024Mar 15, 2025
Class A shares (direct/indirect)11,297 (all underlying options exercisable within 60 days) 18,985 (all underlying options exercisable within 60 days)
% of Class A<1% <1%
Class C shares
Shares pledgedNone disclosed; company policy prohibits hedging/pledging
Economic benefit assignmentObligated to transfer economic benefit from option-exercised shares to BVF Partners L.P.

Governance Assessment

  • Committee effectiveness: Dual membership on Audit and Compensation places Loy at the center of financial reporting oversight and pay-setting governance; Audit has 4 meetings in 2024 and Compensation 2, indicating active oversight cadence . Independence criteria are met for both committees .
  • Independence vs interlocks: Board classifies Loy as independent, but his senior role at BVF Partners and contractual assignment of option economics to BVF creates a material interlock with MLTX’s largest shareholder, posing a perceived conflict and alignment toward a controlling holder rather than broad minority shareholders (RED FLAG) .
  • Attendance: Meets the “≥75%” attendance threshold; no low-attendance risk noted .
  • Director pay mix: Stable cash retainers and annual option grants with time-based vesting; no meeting fees; structure is typical but lacks performance-linked metrics for directors .
  • Compensation committee practices: Use of an independent consultant (Deloitte AG) and no compensation interlocks among committee members reduces pay-setting conflicts .
  • Policy safeguards: Clawback policy for incentive compensation (company-wide); prohibitions on hedging/pledging; formal related party transaction policy with Audit Committee review .

RED FLAGS:

  • Managing Director of BVF Partners, with BVF at ~31% ownership and a contractual obligation for Loy to transfer option economics to BVF, indicates a strong sponsor-shareholder interlock that can challenge perceived independence and minority shareholder alignment .

WATCH ITEMS:

  • Continued monitoring of related party review processes and disclosures regarding any BVF-related transactions; ensure Audit Committee oversight remains robust .
  • Director equity remains options with time-based vesting; absence of performance-conditioned director equity is typical, but alignment should be evaluated given the BVF economics assignment .