Baker Bros. Advisors LP
Baker Bros. Advisors LP is a hedge fund and registered investment adviser headquartered in New York City, founded in 2000 by Julian Baker and Felix Baker. The firm specializes in investments within the biotechnology, life sciences, and healthcare sectors, managing multi-billion dollar portfolios predominantly focused on publicly traded US healthcare companies. Serving institutional and high-net-worth investors, the firm is recognized as one of the most successful healthcare-focused investment managers in the United States.
Investment Strategy
Baker Bros. Advisors employs a fundamentally driven, long-term investment approach with a focus on biotechnology and life sciences companies. The firm invests primarily in public and private healthcare-related securities, including equities, warrants, and convertible debt, concentrating capital in a select group of high-conviction investments. Their strategy involves detailed scientific and financial due diligence, often taking activist or influential roles to support portfolio companies, aiming for superior risk-adjusted returns in the sector.
Top Holdings
Equity Positions (87)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
I INCY | Incyte Corporation | 20.31% | $2.09B | 30,743,275 | $73.57 | $68.10 | +$232.3M |
A ACAD | ACADIA Pharmaceuticals Inc. | 8.98% | $925.3M | 42,896,690 | $15.77 | $21.57 | +$213.1M |
I INSM | Insmed Incorporated | 7.53% | $776.2M | 7,712,900 | $75.94 | $100.64 | +$365.7M |
S SMMT | Summit Therapeutics Inc. | 6.96% | $717.6M | 33,722,974 | $12.25 | $21.28 | +$246.5M |
M MDGL | Madrigal Pharmaceuticals, Inc. | 5.80% | $598.0M | 1,976,018 | $173.16 | $302.64 | -$56.0M |