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Arch Venture Management, LLC
ARCH Venture Management, LLC, headquartered in Chicago, Illinois, is a venture capital firm specializing in seed and early-stage investments in technology-based firms, particularly in information technology, life sciences, and physical sciences. The firm serves entrepreneurs and startups, providing capital, expertise, and support for commercialization. ARCH was founded in 1986 and is part of ARCH Venture Partners, employing a team of professionals with backgrounds in science, technology, and business. It is recognized as one of the leading early-stage venture investors in the United States.
Investment Strategy
ARCH Venture Management focuses on early-stage and seed investments, particularly in companies with groundbreaking commercial potential in sectors such as life sciences, biotechnology, physical sciences, and information technology. The firm looks for transformational opportunities often rooted in university or laboratory innovations, providing not just capital but operational guidance, commercialization resources, and industry access. ARCH is known for its willingness to fund and actively support ventures from their founding through growth and scale, embracing risk to drive major advances in science and technology.
Latest 13F Filing Activity
Arch Venture Management, LLC filed their most recent 13F report on Jun 30, 2025 disclosing 10 equity positions with a total 13F market value of $299M. The fund increased holdings in Vir Biotechnology Inc., Lyell Immunopharma Inc., Verve Therapeutics Inc. among other positions. Arch Venture Management, LLC reduced exposure to Beam Therapeutics Inc., Erasca Inc., Unity Biotechnology Inc. among others.
Top Holdings
Equity Positions (10)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
B BEAM | BEAM THERAPEUTICS INC. | 25.82% | $77.2M | 4,540,132 | $23.05 | $17.01 | -$11.4M |
V VIR | VIR BIOTECHNOLOGY INC. | 21.76% | $65.1M | 12,916,663 | $5.04 | $5.04 | +$65.1M |
M MAZE | MAZE THERAPEUTICS INC. | 16.91% | $50.6M | 4,120,053 | $11.01 | $12.27 | +$5.2M |
R RAPP | RAPPORT THERAPEUTICS INC. | 14.19% | $42.4M | 3,728,738 | $25.44 | $11.37 | +$4.9M |
V VERV | VERVE THERAPEUTICS INC. | 7.54% | $22.6M | 2,008,809 | $36.87 | $11.23 | +$13.4M |
Industry Allocation
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