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New Leaf Venture Partners, L.L.C.

CIK:0001631614
Venture Capital
$53M AUM
8 holdings
New York, NY, United States
Founded:2005
15 employees
Latest filing:Jun 30, 2025

New Leaf Venture Partners, L.L.C. is a venture capital firm headquartered in New York, NY, United States. Founded in 2005, the firm specializes in investments in the healthcare and life sciences sectors, particularly targeting innovative biopharmaceutical, medical device, and diagnostic companies. The firm manages several venture funds and serves a wide range of institutional and strategic investors seeking growth opportunities in transformative healthcare solutions. As of 2025, it holds a portfolio value of approximately $52.95 million and maintains a team of experienced professionals with deep industry expertise.

Investment Strategy

New Leaf Venture Partners focuses on early- to late-stage investments in innovative healthcare and life sciences companies, with a particular emphasis on biopharmaceuticals, medical devices, and diagnostics. The firm seeks to partner with entrepreneurs whose companies have the potential for significant impact on patient outcomes and strong commercial potential. By leveraging deep industry connections and an experienced management team, New Leaf provides capital, strategic support, and operational guidance to portfolio companies through various stages of growth.

Top Buys
P
PASGPASSAGE BIO
+$19.1M
E
EWTXEDGEWISE THERAPEUTICS INC
-$9.2M
R
RLYBRALLYBIO CORPORATION
-$1.0M
C
CRNXCRINETICS PHARMACEUTICALS INC
-$674.0K
A
ARVNARVINAS INC
+$539.1K
Top Sells
P
PASGPASSAGE BIO
+$19.1M
E
EWTXEDGEWISE THERAPEUTICS INC
-$9.2M
R
RLYBRALLYBIO CORPORATION
-$1.0M
C
CRNXCRINETICS PHARMACEUTICALS INC
-$674.0K
A
ARVNARVINAS INC
+$539.1K

Top Holdings

P
PASGPASSAGE BIO
+37.7%$20.0M
E
EWTXEDGEWISE THERAPEUTICS INC
+25.5%$13.5M
A
ARVNARVINAS INC
+22.0%$11.7M
C
CRNXCRINETICS PHARMACEUTICALS INC
+7.7%$4.1M
C
COGTCOGENT BIOSCIENCES INC.
+3.4%$1.8M

Equity Positions (7)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
P
PASG
PASSAGE BIO37.74%$20.0M2,497,922$15.75$8.01+$19.1M
E
EWTX
EDGEWISE THERAPEUTICS INC25.51%$13.5M1,030,161$32.50$13.11-$9.2M
A
ARVN
ARVINAS INC22.04%$11.7M1,585,721$17.10$7.36+$539.1K
C
CRNX
CRINETICS PHARMACEUTICALS INC7.66%$4.1M141,000$27.49$28.76-$674.0K
C
COGT
COGENT BIOSCIENCES INC.3.40%$1.8M250,765$11.17$7.18+$298.4K

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+60.7%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+38.6%