Column Group LLC
The Column Group is a venture capital firm headquartered in San Francisco, California, specializing in early-stage investments in life science companies, particularly across drug discovery, pharmaceuticals, biotechnology, and bioinformatics. Founded in 2007 by Peter Svennilson and Bob More, the firm aims to accelerate groundbreaking scientific discoveries and translate them into commercial therapies. The Column Group operates 12 funds with approximately $4.2 billion in AUM and supports portfolio companies through financial investment, operational expertise, and access to a network of industry experts. The firm's work is focused on supporting researchers and entrepreneurs in the life sciences sector, and it has played a role in the growth and exit of numerous innovative companies.
Investment Strategy
The Column Group deploys a venture-biotech model, investing primarily in early-stage life science companies with strong scientific platforms and the potential to deliver breakthrough therapeutics. The firm targets opportunities at the intersection of biotechnology, pharmaceuticals, and bioinformatics, typically participating from inception through later-stage growth. Its approach includes partnering closely with founders, providing capital, strategic guidance, access to scientific expertise, and operational support. TCG's investment philosophy prioritizes transformational science, long-term company building, and collaboration to move innovations from the lab to the clinic and market.
Top Holdings
Equity Positions (4)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
O ORIC | ORIC Pharmaceuticals Inc. | 54.68% | $35.9M | 3,540,777 | $33.85 | $10.15 | +$16.2M |
R RAPT | RAPT Therapeutics Inc | 16.17% | $10.6M | 1,328,613 | $26.03 | $8.00 | +$9.0M |
T TNYA | Tenaya Therapeutics, Inc. | 8.74% | $5.7M | 9,400,290 | $20.65 | $0.61 | +$385.4K |
R RVMD | Revolution Medicines Inc | 0.00% | $1.7K | 46 | $34.20 | $36.79 | +$65 |