Pivotal Bioventure Partners Investment Advisor LLC
Pivotal bioVenture Partners Investment Advisor LLC is a venture capital firm based in San Francisco, California, founded in 2017. The firm focuses on life sciences, particularly the development of innovative therapeutics. Operating as part of the Pivotal Life Sciences group, the firm backs companies at all stages, from seed to publicly listed, with a preference for leading or co-leading investments and actively supporting company growth. The firm manages more than $689 million in commitments across its funds and serves biotechnology companies in the US and Europe, with a core mission to improve patient outcomes through impactful healthcare innovation. Its team includes seasoned investors and professionals dedicated to nurturing transformative biotech ventures.
Investment Strategy
Pivotal bioVenture Partners invests in North American and European companies developing innovative and impactful therapeutics at all stages, from seed to public listing. The firm prefers to lead or co-lead investments, working closely with entrepreneurs as active board members and company builders. Their core strategy combines deep scientific and clinical expertise, leveraging technology and data analytics—including artificial intelligence—for deal sourcing, due diligence, and portfolio management. They are especially focused on breakthrough technologies, supporting both experienced entrepreneurs and pioneering academics, with an emphasis on creating value through execution excellence and a broad talent network. The firm applies a comprehensive, long-term approach, supporting portfolio companies through late-stage rounds, IPOs, and public market financing, with a particular emphasis on transformative potential in disease management.
Top Holdings
Equity Positions (11)
| Ticker | Security | Weight | Market Value | Shares | Avg Cost | Price | Change (QoQ) |
|---|---|---|---|---|---|---|---|
P PCVX | VAXCYTE INC | 26.30% | $42.4M | 1,305,125 | $33.50 | $32.51 | +$15.6M |
A ARQT | ARCUTIS BIOTHERAPEUTICS INC | 18.43% | $29.7M | 2,120,508 | $12.13 | $14.02 | -$3.4M |
I INZY | INOZYME PHARMA INC | 11.14% | $18.0M | 4,494,851 | $10.48 | $4.00 | +$13.9M |
Z ZBIO | ZENAS BIOPHARMA INC | 4.68% | $7.5M | 779,045 | $15.56 | $9.69 | +$1.7M |
T TRVI | TREVI THERAPEUTICS INC | 3.89% | $6.3M | 1,146,110 | $5.47 | $5.47 | +$6.3M |