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Pivotal Bioventure Partners Investment Advisor LLC

CIK:0001844645
Venture Capital
$689M AUM
12 holdings
San Francisco, CA, United States
Founded:2017
3 employees
Latest filing:Jun 30, 2025

Pivotal bioVenture Partners Investment Advisor LLC is a venture capital firm based in San Francisco, California, founded in 2017. The firm focuses on life sciences, particularly the development of innovative therapeutics. Operating as part of the Pivotal Life Sciences group, the firm backs companies at all stages, from seed to publicly listed, with a preference for leading or co-leading investments and actively supporting company growth. The firm manages more than $689 million in commitments across its funds and serves biotechnology companies in the US and Europe, with a core mission to improve patient outcomes through impactful healthcare innovation. Its team includes seasoned investors and professionals dedicated to nurturing transformative biotech ventures.

Investment Strategy

Pivotal bioVenture Partners invests in North American and European companies developing innovative and impactful therapeutics at all stages, from seed to public listing. The firm prefers to lead or co-lead investments, working closely with entrepreneurs as active board members and company builders. Their core strategy combines deep scientific and clinical expertise, leveraging technology and data analytics—including artificial intelligence—for deal sourcing, due diligence, and portfolio management. They are especially focused on breakthrough technologies, supporting both experienced entrepreneurs and pioneering academics, with an emphasis on creating value through execution excellence and a broad talent network. The firm applies a comprehensive, long-term approach, supporting portfolio companies through late-stage rounds, IPOs, and public market financing, with a particular emphasis on transformative potential in disease management.

Top Buys
P
PCVXVAXCYTE INC
+$15.6M
I
INZYINOZYME PHARMA INC
+$13.9M
T
TRVITREVI THERAPEUTICS INC
+$6.3M
V
VIGLVIGIL NEUROSCIENCE INC
+$3.5M
Z
ZBIOZENAS BIOPHARMA INC
+$1.7M
Top Sells
T
TRVITREVI THERAPEUTICS INC
+$6.3M
V
VIGLVIGIL NEUROSCIENCE INC
+$3.5M
A
ARQTARCUTIS BIOTHERAPEUTICS INC
-$3.4M
Z
ZBIOZENAS BIOPHARMA INC
+$1.7M
B
BOLTBOLT BIOTHERAPEUTICS INC
-$756.6K

Top Holdings

P
PCVXVAXCYTE INC
+26.3%$42.4M
A
ARQTARCUTIS BIOTHERAPEUTICS INC
+18.4%$29.7M
I
INZYINOZYME PHARMA INC
+11.1%$18.0M
Z
ZBIOZENAS BIOPHARMA INC
+4.7%$7.5M
T
TRVITREVI THERAPEUTICS INC
+3.9%$6.3M

Equity Positions (11)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
P
PCVX
VAXCYTE INC26.30%$42.4M1,305,125$33.50$32.51+$15.6M
A
ARQT
ARCUTIS BIOTHERAPEUTICS INC18.43%$29.7M2,120,508$12.13$14.02-$3.4M
I
INZY
INOZYME PHARMA INC11.14%$18.0M4,494,851$10.48$4.00+$13.9M
Z
ZBIO
ZENAS BIOPHARMA INC4.68%$7.5M779,045$15.56$9.69+$1.7M
T
TRVI
TREVI THERAPEUTICS INC3.89%$6.3M1,146,110$5.47$5.47+$6.3M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+41.4%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+30.9%