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Foresite Capital Management VI LLC

CIK:0002013341
Venture Capital
$224M AUM
20 holdings
San Francisco, CA, US
Founded:2011
50 employees
Latest filing:Jun 30, 2025

Foresite Capital Management VI LLC is an entity associated with Foresite Capital, a multi-stage investment firm specializing in healthcare and life sciences markets. Headquartered in San Francisco, CA, the firm leverages data science and domain expertise to invest in biotech and healthcare technology companies. The broader Foresite Capital organization was founded in 2011 and manages multiple funds, serving institutional investors, family offices, and accredited individuals. The employee count at Foresite Capital is estimated at around 50.

Investment Strategy

Foresite Capital Management VI LLC focuses on multi-stage investments across healthcare and life sciences sectors, including biotechnology and healthcare technology startups. The firm employs a data science-driven approach, integrating deep industry expertise and network relationships to identify, evaluate, and support both early and late stage companies. Its investment philosophy emphasizes transforming healthcare through innovation, supporting companies with high scientific and commercial potential, and actively helping portfolio companies scale and achieve meaningful milestones.

Top Buys
R
RAPTRapt Therapeutics Inc
+$12.5M
H
HNGEHinge Health Inc
+$7.0M
V
VSTMVerastem Inc
+$5.3M
X
XENEXenon Pharmaceuticals Inc
+$5.0M
C
CGONCG Oncology, Inc.
+$3.4M
Top Sells
R
RAPTRapt Therapeutics Inc
-$15.3M
A
ALMSAlumis Inc
-$13.1M
E
EWTXEdgewise Therapeutics Inc
-$5.2M
B
BCAXBicara Therapeutics Inc
-$3.6M
G
GPCRStructure Therapeutics Inc
-$2.9M

Top Holdings

C
CGONCG Oncology, Inc.
+32.5%$57.8M
C
CNTACentessa Pharmaceuticals Inc
+9.3%$16.5M
A
AKROAkero Therapeutics Inc
+7.3%$13.1M
A
ALMSAlumis Inc
+7.2%$12.7M
R
RAPTRapt Therapeutics Inc
+7.0%$12.5M

Equity Positions (20)

TickerSecurityWeightMarket ValueSharesAvg CostPriceChange (QoQ)
C
CGON
CG Oncology, Inc.32.47%$57.8M2,221,474$28.68$26.00+$3.4M
C
CNTA
Centessa Pharmaceuticals Inc9.26%$16.5M1,253,379$16.75$13.14-$1.6M
A
AKRO
Akero Therapeutics Inc7.35%$13.1M244,900$27.82$53.36-$1.7M
A
ALMS
Alumis Inc7.16%$12.7M4,247,670$7.81$3.00-$13.1M
R
RAPT
Rapt Therapeutics Inc7.03%$12.5M1,562,500$8.00$8.00+$12.5M

Industry Allocation

PHARMACEUTICAL PREPARATIONS
+55.7%
BIOLOGICAL PRODUCTS, (NO DIAGNOSTIC SUBSTANCES)
+40.9%
SERVICES-COMPUTER PROCESSING & DATA PREPARATION
+3.9%
SERVICES-MEDICAL LABORATORIES
+0.0%