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Foghorn Therapeutics (FHTX)

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Earnings summaries and quarterly performance for Foghorn Therapeutics.

Research analysts covering Foghorn Therapeutics.

Recent press releases and 8-K filings for FHTX.

Foghorn Therapeutics Discusses Pipeline Progress and Recent Financing at TD Cowen Conference
FHTX
New Projects/Investments
Guidance Update
  • Foghorn Therapeutics (FHTX) is a clinical-stage biotech company focused on oncology, with both partnered and proprietary pipelines.
  • The FHD-909 program, partnered 50/50 with Eli Lilly, is in Phase 1 dose escalation for SMARCA2, with a decision on moving to dose expansion anticipated around mid-2026. The company has not yet reached the maximum tolerated dose but is backfilling cohorts.
  • Foghorn's proprietary pipeline includes selective CBP and EP300 degrader programs, with IND-enabling studies on track for later in 2026, and an ARID1B degrader program targeting in vivo proof of concept in 2026.
  • The company recently completed a $50 million registered direct offering in January 2026, which provides approximately two quarters of spend at its current burn rate.
4 days ago
Foghorn Therapeutics Discusses Clinical Progress and Recent Financing
FHTX
New Projects/Investments
Guidance Update
  • Foghorn Therapeutics' FHD-909 program, partnered 50/50 with Eli Lilly, is currently undergoing dose escalation with backfilling for non-small cell lung cancer patients, and a decision on moving to dose expansion is anticipated around mid-2026, plus or minus a few months. The molecule has demonstrated good safety and tolerability to date.
  • The company is advancing its proprietary protein degrader pipeline, with IND-enabling studies planned later in 2026 for selective CBP (FHT-171) and EP300 programs, and in vivo proof of concept targeted for 2026 for the ARID1B degrader.
  • Foghorn Therapeutics completed a $50 million registered direct offering in January 2026, which was priced at a 30% premium to its trading price and provides approximately two quarters of spend at the current burn rate.
4 days ago
Foghorn Therapeutics Provides Clinical Pipeline Update and Recent Financing Details
FHTX
New Projects/Investments
Guidance Update
  • Foghorn Therapeutics is a clinical-stage biotech company focused on oncology, with a pipeline that includes a partnered program with Eli Lilly and proprietary programs.
  • The FHD-909 (SMARCA2) program, partnered 50/50 with Eli Lilly, is currently in dose escalation with backfilling of cohorts, and a decision on moving to dose expansion is anticipated around mid-2026.
  • The company's proprietary pipeline includes selective CBP and EP300 programs, for which IND-enabling studies are expected later in 2026, and an ARID1B degrader program aiming for in vivo proof of concept in 2026.
  • Foghorn completed a $50 million registered direct offering in January, priced at a 30% premium, which provides approximately two quarters of spend coverage at the current burn rate.
4 days ago
Foghorn Therapeutics Provides Update on SMARCA2 Program and Wholly-Owned Pipeline
FHTX
New Projects/Investments
Guidance Update
  • Foghorn Therapeutics' most advanced program, SMARCA2, in collaboration with Eli Lilly, commenced dosing patients in a Phase 1 study in October 2024 for non-small cell lung cancer (NSCLC) patients with SMARCA4 mutations.
  • The collaboration anticipates having sufficient information by mid-2026 to decide on advancing the SMARCA2 program into the dose expansion phase.
  • CEO Adrian Gottschalk expects to see single-agent activity from the SMARCA2 inhibitor, emphasizing the significant unmet need in SMARCA4-mutated NSCLC patients.
  • The company is also progressing wholly-owned programs, including CBP for ER-positive breast cancer, which recently completed non-GLP tox studies, and EP300 for hematological malignancies, tracking for non-GLP tox studies by mid-2026.
Feb 11, 2026, 8:00 PM
Foghorn Therapeutics Provides Update on SMARCA2, CBP, and EP300 Programs
FHTX
New Projects/Investments
Guidance Update
  • Foghorn Therapeutics' most advanced program, SMARCA2, in collaboration with Eli Lilly, began dosing patients in its Phase 1 study in October 2024. A decision on moving to dose expansion is expected around mid-2026.
  • The SMARCA2 program targets non-small cell lung cancer patients with SMARCA4 loss-of-function mutations, representing an estimated 15,000 patients annually in the U.S..
  • For its wholly-owned programs, the CBP program recently completed non-GLP tox studies, with further in vivo work and IND preparation underway for a potential Phase 1 study in ER-positive breast cancer.
  • The EP300 program is on track to begin non-GLP tox studies by mid-2026, targeting hematological malignancies.
Feb 11, 2026, 8:00 PM
Foghorn Therapeutics Provides Update on Oncology Pipeline Development
FHTX
New Projects/Investments
Product Launch
  • The SMARCA2 program, partnered with Eli Lilly, began patient dosing in its Phase 1 study in October 2024. The collaboration anticipates having enough information by mid-2026 to decide on advancing to the dose expansion phase.
  • Foghorn's wholly-owned CBP program, targeting ER-positive breast cancer, recently completed non-GLP toxicology studies with all animals surviving and is moving towards an Investigational New Drug (IND) application.
  • The EP300 program, focused on hematological malignancies, is projected to start non-GLP toxicology studies by mid-2026.
  • The company estimates the annual addressable market for its SMARCA2 inhibitor in non-small cell lung cancer to be approximately 15,000 patients in the U.S..
Feb 11, 2026, 8:00 PM
Foghorn Therapeutics' FHD-286 Drug Response Predicted by Yatiri Bio's Platform
FHTX
New Projects/Investments
  • Yatiri Bio's ProteoCharts™ platform demonstrated 100% concordance in predicting clinical outcomes for Foghorn Therapeutics' FHD-286 in a blinded retrospective study involving patients with relapsed or refractory acute myeloid leukemia (R/R AML) or myelodysplastic syndrome (MDS).
  • The platform accurately identified patients who achieved complete or partial responses (CR/PR) and those who experienced stable disease or treatment failure, using only pre-dose peripheral blood samples.
  • Following this validation, Yatiri Bio and Foghorn Therapeutics signed a collaboration agreement for Foghorn to supply material for the further clinical development of FHD-286, with clinical and sales milestones valued at >$40M.
Feb 10, 2026, 11:00 AM
Foghorn Therapeutics Closes $50 Million Registered Direct Financing
FHTX
  • Foghorn Therapeutics Inc. announced the closing of a $50 million registered direct financing on January 13, 2026.
  • The financing included the sale of 2,030,314 shares of common stock at $6.71 per share, which represented a 30% premium over the Nasdaq Global Market price on January 9, 2026.
  • The offering also involved pre-funded warrants to purchase up to 5,421,250 shares at $6.7099 each and series warrants for up to 3,725,782 shares at $13.42 per share and another 3,725,782 shares at $20.13 per share.
  • Key participants in the financing included existing shareholders BVF Partners, Deerfield Management, and Flagship Pioneering, along with a leading biotech mutual fund.
Jan 13, 2026, 9:05 PM
Foghorn Therapeutics Secures $50 Million Equity Financing and Updates Pipeline Progress
FHTX
New Projects/Investments
Convertible Preferred Issuance
  • Foghorn Therapeutics Inc. raised approximately $50.0 million in an equity financing, which is anticipated to close on January 13, 2026.
  • The financing involved the sale of 2,030,314 shares of common stock at $6.71 per share, pre-funded warrants for 5,421,250 shares, and additional Series 1 and Series 2 warrants for 7,451,564 shares. The offering price for common stock represented a 30% premium to the closing stock price on January 9, 2026.
  • This transaction is expected to result in a strong balance sheet with an estimated $208.9 million in cash, cash equivalents, and marketable securities as of January 13, 2026, extending the cash runway into the first half of 2028.
  • The company provided updates on its pipeline, including the Phase 1 dose-escalation trial of FHD-909 advancing as planned, the Selective CBP degrader program on track to be IND-ready in 2026, and the Selective EP300 degrader program tracking to IND-enabling studies in 2026.
Jan 12, 2026, 1:50 PM
Foghorn Therapeutics Updates on Lilly Partnership and Pipeline Progress
FHTX
New Projects/Investments
Guidance Update
  • Foghorn Therapeutics (FHTX) is a clinical-stage oncology company leveraging a drug discovery engine focused on chromatin biology to target historically undruggable proteins.
  • Its primary program, the SMARCA2 inhibitor FHD-909, is part of a partnership with Eli Lilly, which included $300 million in upfront cash and $80 million in equity. This collaboration involves 50/50 cost-sharing and economics in the U.S. for the SMARCA2 program.
  • Lilly is anticipated to make a decision on advancing FHD-909 into a dose expansion study in H1 2026. The company aims for a 15%+ response rate and 3+ months duration of therapy in the 3rd/4th line setting for SMARCA4 mutant cancers to consider it a success for expansion.
  • Foghorn reported a cash position of $180 million at the end of Q3, which is projected to fund operations into early 2028, covering current program advancements.
Nov 19, 2025, 10:30 AM