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Jake Van Naarden

President, Loxo@Lilly at ELI LILLY &ELI LILLY &
Executive

About Jake Van Naarden

Executive Vice President and President, Loxo@Lilly (Lilly Oncology). Promoted to senior vice president, CEO of Loxo Oncology at Lilly and president, Lilly Oncology, joining the Executive Committee effective September 5, 2021; currently leads Lilly Oncology and corporate business development . He joined Lilly via the 2019 acquisition of Loxo Oncology and has led modernization of Lilly’s oncology portfolio and strategy . 2024 company performance context: Lilly revenue $45.0B, reported EPS $11.71, non-GAAP EPS $12.99, with 2024 TSR of 33% and five-year TSR outperformance versus peers .

Past Roles

OrganizationRoleYearsStrategic Impact
Loxo Oncology at LillyCEO2019 onwardForged Loxo@Lilly R&D program; critical to oncology pipeline success
Lilly OncologyPresident; joined Executive CommitteeEffective Sept 5, 2021Unified Loxo@Lilly and Lilly Oncology; focus and agility for launches and growth
Lilly (Corporate)EVP & President, Lilly Oncology; BD under his leadership2025Expanded scope to lead corporate business development

External Roles

Organization/AreaRoleYearsStrategic Impact
Biotechnology sectorVarious investment, operations, advisory rolesPre-LillyBrought investment and operating expertise to pipeline building

Fixed Compensation

Metric202220232024
Salary ($)$735,577 $830,769 $890,385
Stock Awards – Grant Date FV ($)$1,933,250 $2,424,200 $2,700,248
Non-Equity Incentive (Bonus paid, $)$882,692 $1,503,692 $2,003,366
Target Bonus % of Salary100% 100% (unchanged)

Performance Compensation

Annual Bonus – 2024 Design and Outcome

MetricWeightingTargetActual/AssessmentPayout
Product Revenue (new products)33.3% Internal plan (not disclosed) Exceeded targets after adjustments Included in 225% overall bonus multiple
EPS Performance (adjusted)33.3% Internal plan (not disclosed) Exceeded targets after adjustments Included in 225% overall bonus multiple
Pipeline Progression33.3% Scorecard (discovery, late dev, BD, game-changers) 250% pipeline bonus multiple (no downward discretion) Included in 225% overall bonus multiple

Notes: 2024 total bonus payout = 225% of target for named executive officers, consistent with strong performance ; Jake’s bonus paid = $2,003,366 .

Long-Term Incentives – Structure and Recent Payouts

ProgramMetricPerformance WindowDesign DetailsResult/Payout
Shareholder Value Award (SVA)Absolute stock price vs cost of capital2022–20243-year; payout 0–175%/200% range; 1-year holding after vest 175% payout; Jake shares paid: 6,448.75
Relative Value Award (RVA)TSR vs peer median2022–20243-year; payout 0–175%/200% range; 1-year holding after vest 175% payout; Jake shares paid: 4,926.25
Performance Award (PA)2-year adjusted EPS growth vs peer median2023–2025Performance-adjusted; 13-month service vest; RSUs issued 200% payout; Jake RSUs issued: 4,108 (vesting Feb 1, 2026)

Equity Ownership & Alignment

ItemDetail
Shares Owned (Feb 26, 2025)28,206
Stock Units not distributable within 60 days3,595
Ownership % of outstandingLess than 1% (947,989,151 shares outstanding)
Ownership guidelinesExecutives must hold 6× base salary; retain 50% net shares until compliant; 1-year post-payout hold
Compliance status18× base salary holdings for Van Naarden (as of Dec 31, 2024)
Hedging/PledgingProhibited (no pledging reported)

Employment Terms

ProvisionDetail
Employment agreementsLilly does not enter into employment agreements with executive officers
Non-compete/non-solicit (equity & execs)1-year post-termination restrictive covenants; breach rescinds awards
Non-Compete Payment Agreement (potential)Company may enforce non-compete payment agreement for Van Naarden up to $3,000,000 (less applicable reductions), up to 12 months post-termination
Change-in-Control SeveranceDouble trigger; cash severance equals 2× (base salary + target bonus); 18-month benefits continuation; equity converts/vests per plan; no tax gross-ups; excise tax cutback if beneficial
Jake CIC cash severance$3,600,000 (2× $900,000 salary + 2× $900,000 target bonus)
Continuation of benefits (PV)$65,124 (Jake)
Equity acceleration/continuation under CIC$15,693,911 (Jake; as of 12/31/2024)
Clawback policyRecoupment for restatements, misconduct, inaccurate performance; complies with SEC/NYSE

Vesting Schedules and Realized Values

Upcoming Vesting

AwardShares/UnitsVest DateNotes
2023–2025 PA (RSUs)4,108Feb 1, 202613-month service vest after performance certification
2024–2026 SVATarget 1,310; Max 2,620Dec 31, 20260–200% payout; one-year holding
2024–2026 RVATarget 1,220; Max 2,440Dec 31, 20260–200% payout; one-year holding

2024 Realizations

EventShares Acquired on Vesting (#)Value Realized ($)
2022–2024 RVA payout4,926$4,280,320
2022–2024 SVA payout6,449$5,603,190
RSUs from prior grants (e.g., Dec 2021)3,618$2,962,889

Performance & Track Record

  • 2024 Oncology highlights: sustained Verzenio growth and strong Jaypirca launch; integrated POINT Biopharma to support radio-oncology; positive Phase 3 EMBER-3 (imlunestrant) .
  • Portfolio strategy and modernization: rebuilt oncology team and pipeline; end-to-end span from discovery to commercial .
  • Market perspective: confident Verzenio positioning; CYCLONE-2 registrational prostate cancer program described; disciplined boundaries and event-driven design .
  • Company TSR and financials context: 2024 TSR 33%; five-year TSR outperformance; 2024 revenue $45.0B; adjusted non-GAAP EPS used in incentives .

Compensation Structure Analysis

  • Equity-heavy pay mix with rising grant values: Stock awards increased from $1.93M (2022) to $2.70M (2024) for Van Naarden, reinforcing long-term alignment .
  • Bonus design shifted to equal weighting of product revenue, EPS, and pipeline progression; raised maximum payout to 250% to incentivize delivery of breakthrough medicines .
  • Strong pay-for-performance outcomes: 2024 bonus payout at 225% of target; 2022–2024 SVA and RVA both paid at 175%; 2023–2025 PA paid at 200% .

Say-on-Pay & Shareholder Feedback

  • 2024 say-on-pay received 95% support, indicating broad shareholder alignment with compensation practices .

Compensation Peer Group

  • Peer group includes AbbVie, Amgen, AstraZeneca, Biogen, Bristol-Myers Squibb, Gilead, GSK, Johnson & Johnson, Merck, Novartis, Novo Nordisk, Pfizer, Roche, Sanofi, Takeda; targets benchmarked to comparable market cap/revenue peers .

Equity Ownership & Alignment Details

AspectPolicy/Status
Stock ownership multiple6× base salary required; Van Naarden at 18× (Dec 31, 2024)
RetentionMust hold net shares at least one year; 13-month service vest for PA grants
Hedging/PledgingProhibited; none of executive stock pledged

Employment & Contracts

AspectDetail
Employment agreementsNone for executives
Non-compete durationUp to 12 months post-termination (for non-compete payment agreements); 1-year covenants on equity awards
Change-in-controlDouble trigger; 2× salary+target bonus; 18-month benefits; equity treatment; no tax gross-ups

Risk Indicators & Red Flags

  • Clawback policy robust and compliant (recoupment for restatements/misconduct) .
  • Hedging/pledging prohibited; no pledging reported for executives .
  • No related party transactions required to be reported in 2024 .
  • No routine tax gross-ups in change-in-control plans .

Investment Implications

  • Compensation alignment: Equal-weighted annual metrics and outsized LTI payouts (175–200%) tie rewards to revenue/EPS delivery and pipeline/TSR, supporting long-term equity value creation .
  • Retention risk: Absence of employment contracts is mitigated by robust CIC protections, non-compete enforceability (up to $3M), and significant unvested equity/holding requirements, lowering near-term departure risk .
  • Insider selling pressure: Upcoming vesting (Feb 2026 and Dec 2026) may add supply, but one-year holding requirements and compliance with insider trading procedures temper near-term selling risk .
  • Execution track record: Oncology growth (Verzenio, Jaypirca), portfolio integration (POINT Biopharma), and late-stage readouts position Oncology for continued value creation, with CYCLONE-2 and EMBER-3 milestones as watch items .