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ELI LILLY & (LLY)

Earnings summaries and quarterly performance for ELI LILLY &.

Research analysts who have asked questions during ELI LILLY & earnings calls.

Christopher Schott

JPMorgan Chase & Co.

6 questions for LLY

Also covers: ABBV, AMGN, AMRX +15 more

Courtney Breen

AllianceBernstein

6 questions for LLY

Also covers: ABBV, AMGN, BMY +4 more

Evan Seigerman

BMO Capital Markets

6 questions for LLY

Also covers: ABBV, AMGN, ARVN +15 more

Mohit Bansal

Wells Fargo & Company

6 questions for LLY

Also covers: ABBV, AMGN, BMRN +16 more

Seamus Fernandez

Guggenheim Partners

6 questions for LLY

Also covers: AMLX, ARCT, ARQT +9 more

Steve Scala

Cowen

6 questions for LLY

Also covers: ABBV, AZN, BMY +6 more

Terence Flynn

Morgan Stanley

6 questions for LLY

Also covers: ABBV, AMGN, ARVN +17 more

Akash Tewari

Jefferies

5 questions for LLY

Also covers: ALKS, APLS, ARGX +15 more

Alexandria Hammond

Wolfe Research

4 questions for LLY

Also covers: ABBV, AMGN, BMRN +6 more

Asad Haider

Goldman Sachs

4 questions for LLY

Also covers: ABBV, BMY, BNTX +4 more

David Risinger

Leerink Partners

4 questions for LLY

Also covers: ABBV, AMGN, BMY +9 more

Umer Raffat

Evercore ISI

4 questions for LLY

Also covers: ALKS, AMGN, BHC +15 more

Geoff Meacham

Citigroup Inc.

3 questions for LLY

Also covers: ABBV, AMGN, BMY +8 more

Kerry Holford

Berenberg

3 questions for LLY

Also covers: GSK, NVS, PFE

Tim Anderson

Bank of America

3 questions for LLY

Also covers: ABBV, AMLX, BIIB +4 more

Trung Huynh

UBS Group AG

3 questions for LLY

Also covers: ABBV, ABOS, AMGN +5 more

Chris Shibutani

Goldman Sachs Group, Inc.

2 questions for LLY

Also covers: ABBV, ALKS, BMY +11 more

Geoffrey Meacham

Citi

2 questions for LLY

Also covers: ABBV, BIIB, BMY +6 more

James Chin

Deutsche Bank

2 questions for LLY

James Shin

Analyst

2 questions for LLY

Also covers: ABBV, AMGN, AUTL +7 more

Timothy Anderson

BofA Securities

2 questions for LLY

Also covers: ABBV, AMGN, AZN +10 more

Umar Rafat

Evercore

2 questions for LLY

Alex Hammond

Sidoti & Company, LLC

1 question for LLY

Also covers: BMRN, CBUS, JNJ +1 more

Carter L. Gould

Barclays

1 question for LLY

Also covers: ABBV, ALEC, AMGN +7 more

Jeff Meacham

Citigroup Inc.

1 question for LLY

Also covers: ABOS, NVAX

Kripa Devarakonda

Truist Securities

1 question for LLY

Also covers: ABCL, ARVN, BMY +5 more

Rajesh Kumar

HSBC

1 question for LLY

Also covers: AZN, BZLFY, NVO +2 more

Srikripa Devarakonda

Truist Financial Corporation

1 question for LLY

Also covers: ABCL, ABSI, AFMD +12 more

Recent press releases and 8-K filings for LLY.

Eli Lilly’s Jaypirca meets primary endpoint in Phase 3 head-to-head trial versus Imbruvica
LLY
  • Jaypirca achieved non-inferiority on overall response rate: 87.0% vs. 78.5% for ibrutinib in the intent-to-treat population (nominal p = 0.0035).
  • Progression-free survival trending favorably, with a 43% risk reduction in the ITT population (HR = 0.569) and 76% in treatment-naïve patients (HR = 0.239).
  • Safety profile showed fewer key adverse events versus ibrutinib, including atrial fibrillation/flutter (2.4% vs. 13.5%) and hypertension (10.6% vs. 15.1%), plus lower dose reductions (7.9% vs. 18.2%) and discontinuations (9.4% vs. 10.8%).
  • Phase 3 BRUIN CLL-314 enrolled 662 patients (331 per arm; ITT: 225 treatment-naïve, 437 relapsed/refractory); results to be published in the Journal of Clinical Oncology and presented at ASH 2025.
1 day ago
Eli Lilly Gains Full FDA Approval for Jaypirca in CLL/SLL Treatment
LLY
  • FDA grants full traditional approval to Jaypirca for relapsed/refractory CLL/SLL after covalent BTK inhibitor, upgrading from accelerated approval in December 2023.
  • Phase 3 BRUIN-CLL-321 trial demonstrated median progression-free survival of 11.2 months versus 8.7 months for comparators.
  • Jaypirca, the only non-covalent BTK inhibitor approved for this indication, is available in 50 mg and 100 mg tablet formulations.
  • Eli Lilly’s stock price was $1,039.16, down 0.67%, following the FDA announcement.
5 days ago
Eli Lilly’s Jaypirca receives expanded FDA approval for CLL/SLL
LLY
Product Launch
  • U.S. FDA granted traditional approval for Jaypirca (pirtobrutinib) in adults with relapsed or refractory CLL/SLL previously treated with a covalent BTK inhibitor, converting its December 2023 accelerated approval to a full approval.
  • Jaypirca is the first and only FDA-approved non-covalent (reversible) BTK inhibitor, offering continuity in BTK pathway targeting after covalent BTK inhibitor therapy.
  • The label expansion allows physicians to use Jaypirca earlier in the treatment course immediately following covalent BTK inhibitor failure.
  • Approval is supported by the BRUIN CLL-321 Phase 3 trial, which randomized 238 patients 1:1 to Jaypirca versus investigator’s choice (idelalisib + rituximab or bendamustine + rituximab) with progression-free survival as the primary endpoint.
5 days ago
Lilly outlines US obesity commercial strategy and pipeline at Citi Healthcare Conference
LLY
Product Launch
Guidance Update
  • Lilly USA will prioritize expanding obesity treatment as a chronic disease, anticipate the Orforglipron launch in early Q2 2026, and continue to innovate consumer offerings like LillyDirect and partnerships with retailers such as Walmart
  • Medicare access may begin April–July 2026, covering ~80% of on-label patients with a $50/month copay; Medicaid coverage ramp is expected in 2027, and direct-to-consumer pricing for Zepbound has been reduced by $50 per dose
  • LillyDirect serves as a transparent, frictionless patient channel, responsible for ~45% of Zepbound new starts, and will expand to include Orforglipron
  • Orforglipron is positioned as a key oral entry and maintenance therapy alongside injectable Zepbound; Cagrilintide showed strong monotherapy data at Obesity Week with combination trials planned for 2026
  • The White House MFN agreement secures fixed U.S. pricing for incretins, and ties launches of non-incretin drugs to G7+ reference pricing, influencing global reimbursement strategies
6 days ago
Lilly outlines 2026 obesity access strategy at Citi Healthcare Conference
LLY
Product Launch
  • Medicare coverage for obesity treatments to begin April–July 2026, covering ~80% of on-label patients with a $50/month co-pay; Medicaid access will improve in 2026 but likely won’t fully ramp until 2027.
  • Oral GLP-1 (orfagliptron) set to launch in early Q2 2026 as an entry and maintenance option alongside injectable tirzepatide (Zepbound), expanding patient choice and overall market penetration.
  • Lilly Direct now drives ~45% of new obesity treatment starts, offering telehealth, transparent pricing, and home delivery; self-pay prices have been cut by ~$50/month, complemented by a Walmart pickup partnership and employer programs to boost access.
  • U.S. White House agreement secures broad incretin access and ties future non-incretin launches to MFN pricing versus G7 + Denmark & Switzerland (excluding the lowest), impacting OUS pricing especially in immunology and oncology while emphasizing value demonstration abroad.
6 days ago
Lilly outlines obesity strategy and pipeline priorities at Citi Global Healthcare Conference 2025
LLY
Product Launch
  • Obesity as chronic disease: Ilya Yuffa highlighted an early-Q2 2026 launch of oral Orforglipron and a Medicare deal covering ~80% of on-label patients at $50/month (effective April–July 2026), with Medicaid access expected to ramp in 2027.
  • Commercial mix and access: Zepbound (tirzepatide) is now standard of care; oral Orforglipron will serve as both an entry and maintenance option. Approximately 45% of new starts occur via LillyDirect, supported by new self-pay pricing of $299–$449 per month.
  • Pipeline expansion: Focus on cardiometabolic adjacencies (e.g., sleep apnea), high-risk areas like inflammation and neuropsychiatry, and advancing amylin agonist eloralintide with combination studies alongside tirzepatide planned for next year.
  • Non-incretin catalysts: Alzheimer’s candidate Kisunla aims to leverage blood-based biomarkers and adjuvant settings; Ebglyss is targeting first-line atopic dermatitis uptake; Jaypirca’s CLL label expansion is expected imminently.
6 days ago
Eli Lilly analysts raise price targets amid pipeline strength and price cuts
LLY
Product Launch
New Projects/Investments
  • Analysts including BMO Capital (Outperform, $1,100 PT), Bank of America (Buy, $1,286 PT), Berenberg ($950 PT) and Morgan Stanley (Buy, $1,290 PT) have raised or maintained ratings on Eli Lilly following strong Q3 results and strategic pricing moves.
  • Eli Lilly will cut cash-pay prices for Zepbound starter vials to $299 per month, with additional reductions for higher-dose forms, building on a prior agreement to lower multi-dose prices.
  • The oral GLP-1 candidate orforglipron received one of the FDA’s first National Priority Vouchers and is now expected to launch in early 2026, accelerated from prior timelines.
  • Ongoing pipeline highlights include the TRIUMPH-4 Phase 3 trial for retatrutide (results due year-end) and upcoming EMBER-3 breast cancer data at the December 2025 San Antonio symposium.
7 days ago
Eli Lilly cuts Zepbound prices to expand obesity drug access
LLY
  • Zepbound single-dose vial prices on LillyDirect reduced by up to 20%, with the starting dose now $299/month (from $349), the 5 mg dose $399 (from $499), and higher doses $449 (from $499); additional discounts apply through the Zepbound Self-Pay Journey Program for refills within 45 days.
  • These reductions complement earlier cuts for multi-dose pens and stem from a deal with the Trump administration that also introduces Medicare coverage for eligible patients and a new government DTC website.
  • Despite cuts, Zepbound’s list price remains around $1,086/month, and insufficient U.S. insurance coverage continues to pose a barrier for patients.
  • The move underscores intensifying competition with Novo Nordisk, which has similarly announced discounts on its obesity and diabetes treatments.
8 days ago
Lilly to present two Phase 3 Jaypirca study results at ASH 2025
LLY
  • Lilly will share full data from two positive Phase 3 studies of Jaypirca (pirtobrutinib) at the 67th ASH Annual Meeting, Dec. 6–9 in Orlando.
  • The BRUIN CLL-314 trial, the first head-to-head Phase 3 comparing non-covalent pirtobrutinib to covalent ibrutinib in treatment-naïve CLL/SLL, met its primary non-inferiority endpoint with a nominal P-value < 0.05 favoring pirtobrutinib.
  • The BRUIN CLL-313 study versus chemoimmunotherapy in treatment-naïve CLL/SLL (without del(17p)) demonstrated a highly significant and clinically meaningful improvement in progression-free survival with pirtobrutinib.
  • Additional oral and poster presentations will cover long-term follow-up from the Phase 1/2 BRUIN study in relapsed/refractory CLL, mantle cell lymphoma, Waldenström macroglobulinemia, and investigator-initiated combination regimens.
Nov 24, 2025, 5:00 PM
Eli Lilly and Novo Nordisk launch direct-to-employer obesity drug model
LLY
New Projects/Investments
  • Starting January 1, 2026, Novo Nordisk and Eli Lilly will sell FDA-approved weight loss drugs such as Wegovy and Zepbound directly to self-insured and large employers, bypassing PBMs at fixed upfront prices to reduce costs and improve transparency.
  • The program, powered by Waltz Health’s AI-driven platform (acquired by EVERSANA in August 2025), provides real-time eligibility screening, prescription routing, adherence monitoring, and an integrated telehealth option for seamless access and clinical safeguards.
  • Eli Lilly’s approach includes flexible benefit design, a dedicated pharmacy network for enhanced cost tracking, and collaborations with third parties to deliver holistic weight management solutions.
  • Both companies aim to eliminate unapproved compounded versions of their GLP-1 obesity drugs and help employers tailor benefits, targeting a market projected to reach $150 billion annually by the early 2030s.
Nov 21, 2025, 7:15 PM